Publications by authors named "Xiaoyong Wu"

Postmenopausal osteoporosis is a common degenerative disease, with suboptimal clinical outcomes. The targets of current therapeutic agents are both nonspecific and diverse. We synthesized a novel nanoparticle (NP), ALN@BMSCM@PLGA-TK-PEG-SS31.

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The role of defect regulation of transition metal catalysts in peracetic acid (PAA) activation is equivocal. To reveal the corresponding mechanism, this work provides a high-efficiency and eco-friendly catalyst (MoO) for PAA activation by introducing various degrees of oxygen vacancies on the MoO surface. Interestingly, 95.

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Single-atom iridium was interfacially engineered on CuFeS quantum dots (QDs) with highly efficient CO photoreduction performance. The electronic structure modulation yielded a remarkable CO yield rate of 32.5 μmol g h with 92.

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Objectives: Temporomandibular disorders (TMDs) are one of the leading causes of craniofacial pain, and a high incidence of TMDs in young adults has been reported. Previous studies have used surface electromyography (sEMG) and mandibular kinematic analysis for TMDs diagnosis. This study aimed to provide normal reference values of sEMG and mandibular kinematics in Han Chinese adults, compare the sex differences and assess their diagnosis value on pain-free articular TMDs.

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  • The study focuses on predicting hepatic encephalopathy (HE) in patients with acute-on-chronic liver failure (ACLF) to improve patient outcomes through early detection and intervention.
  • Conducted on 255 hepatitis B-related ACLF patients, it identified significant clinical predictors such as blood urea nitrogen and serum ammonia using a logistic regression model, achieving a high predictive accuracy (AUROC of 85.2%).
  • The newly developed model was validated in a separate group of patients, showing promising results, indicating its potential as a reliable tool for identifying those at high risk of developing HE.
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  • The study investigates the role of SLAMF8 in bone healing by analyzing its effects on inflammatory responses and osteogenesis in mouse bone marrow mesenchymal stem cells (mBMSCs).
  • Researchers utilized GEO datasets and various molecular techniques to assess how SLAMF8 influences genes related to bone formation (like RUNX2 and COL1A1) and fat formation (like PPARγ).
  • Results showed that knocking down SLAMF8 reduced bone formation and increased fat formation in mBMSCs, while its overexpression enhanced bone healing in a femoral fracture model.
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  • Controlled low oxygen levels boost the ability of bone marrow mesenchymal stem cells (BMSCs) to turn into bone-forming cells and produce calcium nodules, but the specific processes behind this are not well-understood.
  • The study investigates how hypoxia affects BMSCs and highlights the role of FUNDC1, a factor that influences mitochondrial function, particularly during low-oxygen conditions.
  • Findings reveal that FUNDC1 promotes bone formation not through mitophagy but by enhancing mitochondrial fission, which helps stabilize a protein called HIF1α, crucial for BMSC differentiation.
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The pancreas is a rare metastatic site for lung cancer. We report the case of a 66-year-old male with pulmonary sarcomatoid carcinoma (PSC) with pancreatic and right posterior renal fascia metastases treated with immunotherapy and platinum-based chemotherapy. A pathological biopsy of the right posterior fascial mass showed lung invasive adenocarcinoma and sarcomatoid carcinoma metastasis.

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In clinical settings, addressing large bone defects remains a significant challenge for orthopedic surgeons. The use of genetically modified bone marrow mesenchymal stem cells (BMSCs) has emerged as a highly promising approach for these treatments. Signal peptide-CUB-EGF domain-containing protein 3 (SCUBE3) is a multifunctional secreted glycoprotein, the role of which remains unclear in human hBMSCs.

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  • Researchers created advanced two-terminal monolithic perovskite/silicon tandem solar cells, achieving higher power conversion efficiency than single-junction solar cells.
  • They addressed the challenge of reducing interfacial recombination by developing a unique bilayer passivation strategy using lithium fluoride and diammonium diiodide, which improved charge extraction and reduced energy loss.
  • The improved tandem cells demonstrated a certified power conversion efficiency of 33.89%, surpassing the single-junction Shockley-Queisser limit and achieving strong performance metrics such as an open-circuit voltage of 1.97V.
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Tartary buckwheat sprouts are highly valued by consumers for their superior nutritional content. Ionic titanium (Ti) has been shown to enhance crop growth and improve nutritional quality. However, there is limited research on the impact of ionic Ti on the nutritional quality of Tartary buckwheat sprouts.

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  • Molecular phylogenetic research focuses on analyzing coding sequences of genes and amino acid sequences to identify mutations and their impact on evolution.
  • Specific amino acids have quantifiable characteristics that can convert these sequences into numerical representations, allowing for a more comprehensive analysis of evolutionary processes beyond just counting mismatches.
  • Advanced analytical techniques, including bivariate wavelet analysis and matrix comparisons, improve the understanding of protein evolution and help resolve discrepancies in taxonomic trees, with automation available in R for further applications.
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Developing a feasible and low-cost strategy for the recovery of calcium fluoride efficiently from fluoride-containing wastewater is very essential for the recycle of fluoride resources. Herein, a modified lime precipitation method was employed to recover CaF from fluorinated wastewater using a special icy lime solution. Intriguingly, the highest F removal was greater than 95% under the optimal condition, leaving a fluoride concentration from 200 to 8.

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Introduction: Stereotactic body radiation therapy (SBRT) is a treatment for patients with early-stage non-small cell lung cancer (ES-NSCLC). Surveillance guidelines vary after treatment. While patients are more likely to locally recur within 2 years of treatment, there remains a paucity of data on the benefit of frequent and long-term surveillance.

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Quinoa ( Willd) is widely regarded as a versatile pseudo-cereal native to the Andes Mountains in South America. It has gained global recognition as a superfood due to its rich nutritional profile. While quinoa grains are well-known, there is an undiscovered potential in quinoa greens, such as sprouts, leaves, and microgreens.

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Objective(s): To assess the influence of treatment package time (TPT) on overall survival (OS) and event free survival (EFS) in oral cavity cancer (OCC) patients treated with surgery and adjuvant radiation therapy (RT) with or without concurrent chemotherapy (CHT).

Materials/methods: 354 adult OCC patients treated at a single, high-volume center between 2012-2022 with various pathologic risk features were included. TPT was defined as days from surgery to RT completion.

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Purpos: To evaluate the clinical efficacy of the Medial Sustain Nail (MSN) for medial comminuted trochanteric fractures fixation in comparison to Proximal Femoral Nail Antirotation (PFNA) through a clinical study.

Methods: A non-inferiority randomized controlled trial was conducted at a single centre between July 2019 and July 2020. Fifty patients diagnosed comminuted trochanteric fractures were randomly assigned to either the MSN group (n = 25) or the PFNA group (n = 25).

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To identify the role of enterotoxin-related genes in colorectal cancer (CRC) development and progression. Upregulated differentially expressed genes shared by three out of five Gene Expression Omnibus (GEO) data sets were included to screen the key enterotoxin-induced oncogenes (EIOGs) according to criteria oncogene definition, enrichment, and protein-protein interaction (PPI) network analysis, followed by prognosis survival, immune infiltration, and protential drugs analyses was performed via integration of RNA-sequencing data and The Cancer Genome Atlas-derived clinical profiles. We screened nine common key EIOGs from at least three GEO data sets.

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Nonunion is a challenging complication of fractures for the surgeon. Recently the Lys-Asp-Glu-Leu (KDEL) endoplasmic reticulum protein retention receptor 2 (KDELR2) has been found that involved in osteogenesis imperfecta. However, the exact mechanism is still unclear.

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Background: The prognostic value of Toll-like receptor 4 (TLR4) in breast cancer remains to be determined. Therefore, this paper aims to conduct a meta-analysis to assess the correlation between TLR4 and clinicopathological indicators as well as survival outcomes in breast cancer.

Method: Related literature retrieved from Embase, PubMed, Cochrane Library, Web of Science, China National Knowledge Infrastructure (CNKI) and China Wanfang.

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Quinoa (Chenopodium quinoa Willd.) microgreens are widely consumed as healthy vegetables around the world. Although soluble dietary fibers exist as the major bioactive macromolecules in quinoa microgreens, their structural characteristics and bioactive properties are still unclear.

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Regulating product selectivity in photocatalytic CO reduction to enhance the yield of valuable hydrocarbons remains a formidable challenge because of the diversity of reduction products and the competitive reduction of HO. Herein, ultrathin BiO/ Co-doped SrBiTiO S-scheme photocatalysts (Co-BS) were synthesized using a hydrothermal method. The BiO/Co-doped SrBiTiO photocatalyst exhibited significantly higher selectivity for CH (62.

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Regulation of peroxymonosulfate (PMS) activation from radical to non-radical pathways is an emerging focus of advanced oxidation processes (AOPs) due to its superiority of anti-interference to complex wastewater. However, the detailed correlation mechanism between the defect structure of the catalyst and the regulation of radicals/non-radicals remains unclear. Herein, natural chalcopyrite (CuFeS) with different levels of S vacancies created by a simple NaBH reduction process was employed to explore the above-mentioned underlying mechanism for constructing high efficiency and low cost of catalyst towards AOPs.

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Background: Xuebijing (XBJ) is widely applied in the treatment of Acute Lung Injury (ALI). This study focused on the potential mechanism of XBJ in Lipopolysaccharide (LPS)-induced ALI.

Methods: The rat ALI model was established by injection of LPS (10 mg/kg) and pretreated with XBJ (4 mL/kg) three days before LPS injection.

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The economic and health significance of quinoa is steadily growing on a global scale. Nevertheless, the primary obstacle to achieving high yields in quinoa cultivation is pre-harvest sprouting (PHS), which is intricately linked to seed dormancy. However, there exists a dearth of research concerning the regulatory mechanisms governing PHS.

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