Publications by authors named "Xiaoye Hu"

Objectives: To investigate the meta-epidemiology and reporting characteristics of mapping reviews.

Study Design And Setting: We conducted a scoping review of a sample of recent mapping reviews (2022-2023) by searching nine electronic databases and eleven institutional websites up to January 2024. A 28-item reporting checklist, developed by our team and based on existing guidance and methodological studies of mapping reviews, was employed to assess reporting characteristics.

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  • * A novel miR-nanosponge has been created to simultaneously capture multiple miRs linked to GBM growth and spread, improving therapeutic outcomes by addressing the cancer's compensatory mechanisms.
  • * This miR-nanosponge, coated with BV2 cell membranes to better penetrate the blood-brain barrier, has shown to significantly prolong survival in GBM-bearing mice, surpassing the effectiveness of the standard drug temozolomide (TMZ).
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Tuning the adsorption energy of nitrogen intermediates and lowering the reaction energy barrier is essential to accelerate the kinetics of nitrogen reduction reaction (NRR), yet remains a great challenge. Herein, the electronic structure of WS is tailored based on a metal and nonmetal dual-doping strategy (denoted Fe, F-WS) to lower the d-band center of W in order to optimize the adsorption of nitrogen intermediates. The obtained Fe, F-WS nanosheet catalyst presents a high Faradic efficiency (FE) of 22.

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Introduction: Desmoid tumor (DT) is a rare proliferative disease occurring in connective tissues, characterized by high infiltration and recurrence rates. While surgery remains the primary treatment, its recurrence risk is high, and some extra-abdominal desmoid tumors are inoperable due to their locations. Despite attempts with radiotherapy and systemic therapy, the efficacy remains limited.

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The modulation of the chemical microenvironment surrounding metal nanoparticles (NPs) is an effective means to enhance the selectivity and activity of catalytic reactions. Herein, a post-synthetic modification strategy is developed to modulate the hydrophobic microenvironment of Ru nanoparticles encapsulated in a metal-organic framework (MOF), MIP-206, namely Ru@MIP-F (where x represents perfluoroalkyl chain lengths of 3, 5, 7, 11, and 15), in order to systematically explore the effect of the hydrophobic microenvironment on the electrocatalytic activity. The increase of perfluoroalkyl chain length can gradually enhance the hydrophobicity of the catalyst, which effectively suppresses the competitive hydrogen evolution reaction (HER).

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  • Traditional SERS sensors, often made from expensive noble metals, face issues like high costs and instability, prompting the need for alternative materials.
  • This study showcases molybdenum boride ceramic powders as a promising SERS platform, achieving an impressive enhancement factor and a high detection limit for the dye rhodamine 6G.
  • The ceramic's excellent SERS activity, especially from the β-MoB phase, is maintained even under extreme conditions, highlighting its potential for use in challenging detection environments.
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Silicon carbide (SiC) aerogels, which possess unique porous structure and high ablation resistance, show great potential as thermal insulation materials, but their wide application is limited by expensive and cumbersome synthetic procedures. Therefore, it is pivotal to develop a facile, versatile, and cost-effective method for producing SiC aerogels. Herein, we have successfully prepared ultra-light SiC nanowire aerogels (SNWAs) boasting remarkably low thermal conductivity, using biomass-derived carbon templates (BCTs) through a direct carbothermal reduction method.

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  • * Lepidocrocite VOOH nanoparticles (less than 30 nm) were created using a mild hydrothermal method, with the Kirkendall effect aiding their growth, and these can be transformed into VO through annealing.
  • * The resulting ultrafine VO nanoparticles exhibit strong thermochromic performance, with a transmittance increase from 56.45% to 62.29% when coated with a silicon dioxide (SiO) shell, highlighting their potential for durable and efficient smart window applications.
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Background: Although non-pharmacological smoking cessation measures have been widely used among smokers, current research evidence on the effects of smoking cessation is inconsistent and of mixed quality. Moreover, there is a lack of comprehensive evidence synthesis. This study seeks to systematically identify, describe, and evaluate the available evidence for non-pharmacological interventions in smoking populations through evidence mapping (EM), and to search for best-practice smoking cessation programs.

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  • Surface-enhanced Raman scattering (SERS) is a sensitive analytical technique, but practical use has been limited by the scarcity of effective hotspots on existing substrates.
  • Researchers created a flexible three-dimensional (3D) SERS substrate using silver nanoparticles (Ag NPs) and carbon aerogels (CAs), allowing multiple hotspots that can be adjusted for improved sensitivity.
  • This innovative SERS substrate has a low detection limit for rhodamine 6G and can be used to detect thiram on cherry tomatoes, showing promise for environmental monitoring applications.
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Glioblastoma (GBM), the most common subtype of malignant gliomas, is characterized by aggressive infiltration, high malignancy, and poor prognosis. The frustrating anti-GBM outcome of conventional therapeutics is due to the immunosuppressive milieu, in addition to the formidable obstacle of the blood-brain barrier (BBB). Combination therapy with an immune checkpoint blockade (ICB) has emerged as a critical component in the treatment of GBM.

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Background: Desmoid tumors are rare neoplasms that are locally invasive. However, optimal treatment strategies for recurrent desmoid tumors remain controversial. High-intensity focused ultrasound (HIFU) has been reported as a noninvasive modality for treating recurrent desmoid tumors.

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In this work, a strategy of using fast co-precipitation method has been developed to synthesize stable Al doped α-phase NiCo layered double hydroxides (NCA-LDH). A subsequent surface sulphuration of NCA-LDH (S-NCA-LDH) was carried out to improve the conductivity. The as-synthesized S-NCA-LDH exhibits a good electrochemical performance with a specific capacity of 727.

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Background: Nuclear transcription factor Y subunit C antisense RNA 1 (NFYC-AS1) was revealed to be a potential prognostic biomarker in lung adenocarcinoma (LAUD) by analyzing The Cancer Genome Atlas (TCGA) database. However, the function of NFYC-AS1 has not been verified in cancers, including LAUD. We plan to verify the function of NFYC-AS1 in LAUD through this study.

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Purpose: To compare the survival benefit, pain control and safety of low-power cumulative and traditional high-intensity focused ultrasound (HIFU) for metastatic pancreatic cancer.

Method: We retrospectively analyzed 55 patients with metastatic pancreatic cancer who received HIFU treatment between January 2008 and April 2014 in our department. 23 patients received low-power cumulative HIFU treatment (L group), 32 received the traditional HIFU treatment (T group).

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Introduction: Desmoid-type fibromatosis (DF) is a fibrous tumor characterized by low-grade malignant and easy invasive growth and high recurrence. High-intensity focused ultrasound (HIFU) therapy has been identified as a novel non-invasive approach for DF treatment; however, the ultrasonic energy generated by HIFU can cause skin heat injury.

Case: A 31-year-old female patient with signs and symptoms of DF received treatment in our institution.

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Myxofibrosarcoma is a common soft-tissue sarcoma in elderly patients, characterized by an infiltrative growth pattern and a high risk for persistent local recurrence. A 35-years-old woman was diagnosed with myxofibrosarcoma on the right upper arm and the tumor is surgically resected. The tumor relapsed 7 months later.

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Uterine leiomyosarcoma has the characteristics of high malignancy, a poor prognosis, and a high recurrence rate. Surgery is the main treatment option, supplemented by chemotherapy and radiotherapy. We report on a patient with recurrent uterine leiomyosarcoma who was treated with high-intensity focused ultrasound combined with chemotherapy.

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An amendment to this paper has been published and can be accessed via a link at the top of the paper.

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It is of great significance to develop a simple and effective method for constructing large-scale high-quality surface-enhanced Raman scattering (SERS) substrate. Here, an Ag nanoparticle-assembled micro-bowl array was prepared by a close-packed polystyrene (PS) sphere monolayer templated electrodeposition approach. The fabricated Ag nanoparticle-assembled micro-bowl array shows high SERS sensitivity to rhodamine 6G (R6G) under an ultra-low concentration of 1 fM, and exhibits excellent SERS spectral uniformity with a small relative standard deviation (RSD) of 7.

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  • A new split-type SERS (Surface-Enhanced Raman Scattering) substrate has been developed, featuring a combination of Al2O3@Ag@Si nanocone arrays and Ag nanoparticles (Ag-NPs) for improved sensitivity and stability.
  • The substrate is created by coating a silicon nanocone array with an ultra-thin layer of Al2O3 after ion-sputtering silver, while the Ag-NPs are synthesized separately and later combined for SERS measurement.
  • This innovative design allows the substrate to detect Rhodamine R6G at very low concentrations (1 pM) with a high enhancement factor, maintaining its performance over time due to effective protection against oxidation.
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Polycyclic aromatic hydrocarbons (PAHs) are one of the most widespread and dangerous group of pollutants existing in the environment. Trace detection of PAHs is essential and important. Surface-enhanced Raman scattering (SERS) is a powerful analytical tool for ultrasensitive chemical analysis.

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Both entecavir and crizotinib are substrates of organic cation transporter 2 (OCT2). The aim of present study was to investigate the mechanisms of drug interactions between these two drugs. Kinetic analysis of entecavir on crizotinib uptake was conduct.

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The gray level run length matrix (GLRLM) whose entries are statistics recording distribution and relationship of images pixels is a widely used method for extracting statistical features for medical images, e.g., magnetic resonance (MR) images.

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