Development and validation of matrix metalloproteinase for predicting prognosis and tumour microenvironment immune profiles in uterine corpus endometrial carcinoma.

: Matrix metalloproteinases (MMPs) are involved in many processes of tumour progression and invasion. However, few studies have analysed the effects of MMP expression patterns on endometrial cancer (EC) development from the perspective of the tumour microenvironment (TME). we quantified MMP expression in individual by constructing an MMP score and found MMP score effectively predict the prognosis of EC patients.

ILSHIP: An interpretable and predictive model for hypothyroidism.

Hypothyroidism is one of the common endocrine diseases, and its incidence is increasing year by year. Due to the insidious nature of this disease, it often leads to delayed treatment and even misdiagnosis. This paper proposes ILSHIP, an interpretable predictive model for hypothyroidism, to reduce its diagnostic complexity as well as improve the predictive performance and interpretability of existing models.

DHDIP: An interpretable model for hypertension and hyperlipidemia prediction based on EMR data.

Background And Objective: Traditional hypertension and hyperlipidemia prediction models suffer from uneven modeling data sources, small sample sizes, and a lack of uniform standards for the index system, resulting in the model failing to fulfill clinical applications. To address this issue, this work will offer DHDIP, an interpretable hypertension and hyperlipidemia prediction model based on EMR data.

Methods: First, we will select massive high-dimensional, unstructured EMR data as a unified modeling data source, and propose a pre-processing algorithm for EMR data to solve the problem that EMR data cannot be directly processed by machine learning algorithms.

Mechanical Performance of Single-Graded Copolymer-Modified Pervious Concrete in a Corrosive Environment.

Polymer-modified cement has found numerous applications due to its excellent tensile strength. When cement was modified with a single polymer, its tensile strength and performance marginally increased. However, when a small amount of the flexible polymer latex was added to cement, the mechanical performance of cement considerably improved.

Toughness Behavior of SBR Acrylate Copolymer-Modified Pervious Concrete with Single-Sized Aggregates.

Pervious concrete is an eco-efficient concrete but has problems regarding its mechanical performance and permeability balance. This research investigated the feasibility of using a combination of styrene-butadiene rubber (SBR) and acrylate polymer to improve the toughness of pervious concrete while keeping its permeability. Single-sized aggregate and no sand were considered in the concrete mixture.