Research on the Properties of Wasteforms after Direct Involvement of Uranium-Containing Silica Gel in Glass Network Formation.

Uranium-containing silica gel (UCSG) is a secondary waste generated during the advanced treatment of nuclear wastewater. In order to reduce the growing storage pressure for UCSG, from the perspective of building a borosilicate glass network, UCSG was used to replace SiO in the glass-cured formula to directly achieve the immobilization of UCSG. SEM-EDS results showed that uranium was uniformly distributed in the matrix, and the maximum solid solubility of UCSG (two components: silica gel and uranyl ions) in the formula was as high as 55 wt %.

Experimentally and Theoretically Revealing the Co-Doping Effects of Ce-Sr in GdZrO.

To safely dispose radioactive waste (including, e.g., thorium and radiostrontium), Ce and Sr were chosen as simulated surrogates of α and β waste and were introduced into the Gd site in GdZrO to maintain the average cationic radius and to compensate for charge.

Oligo(-phenylenes)s-Oligoarginine Conjugates as Effective Antibacterial Agents with High Plasma Stability and Low Hemolysis.

Bacterial infections have become a global threat to human health, and the design of antibacterial agents is always an urgent task for biomedicine. Amphiphilic antibacterial agents with a different mechanism of action from traditional antibiotics have attracted researchers' attention more and more in recent years. In this work, a series of antibacterial conjugates composed of oligo(-phenylenes)s and oligoarginine were synthesized, and their antibacterial activity was investigated.

Rapid solidification of Sr-contaminated soil by consecutive microwave sintering: mechanism and stability evaluation.

Consecutive microwave sintering is a method proposed in this study to dispose soil contaminated by Sr during a nuclear accident by rapidly solidifying the contaminated soil. The results show that soil contaminated with 20 wt% SrSO and 30 wt% SrSO can be completely solidified by microwave sintering at 1100-1200 and 1300 ℃, respectively, for 30 min. Sr was found to be cured into slawsonite (SrAlSiO) and glass structures.

Heavy-ion irradiation effects on uranium-contaminated soil for nuclear waste.

In the field of radioactive waste immobilization, the investigation of irradiation stability is of considerable importance. In this study, uranium-contaminated soil samples were irradiated by 1.5 MeV Xe ions with fluences ranging from 1 × 10 to 1 × 10 ions/cm.

Low-sintering-temperature borosilicate glass to immobilize silver-coated silica-gel with different iodine loadings.

To better deal with the radioactive iodine generated during the development of nuclear energy, BO, BiO, ZnO, and SiO were used to sinter borosilicate glass for the immobilization of iodine. The effect of BO on glass formation was discussed by changing the molar ratio of BO in the matrix. When BO content is 50 mol% and sintering temperature is 600 ℃, the amorphous degree of quaternary glass is the highest.

Long non-coding RNA NEAT1 promotes human glioma tumor progression via miR-152-3p/CCT6A pathway.

Background: Long non-coding RNA (lncRNA) nuclear enriched abundant transcript 1 (NEAT1) has been documented to implicate in diverse tumor progression. However, the mechanism of NEAT1 in glioma was rarely reported.

Methods: The levels of NEAT1, microRNA-152-3p (miR-152-3p) and chaperonin containing TCP1 subunit 6A (CCT6A) in glioma tissues and cells were measured by quantitative real-time polymerase chain reaction (qRT-PCR).

Heavy-ion irradiation effects on UO incorporated GdZrO waste forms.

In this research, the heavy-ion irradiation effects of U-bearing GdZrO ceramics were explored for nuclear waste immobilization. UO was designed to be incorporated into GdZrO from two different routes in the form of (GdU)(ZrU)O (x = 0.1, 0.

Long noncoding RNA: multiple players in gene expression.

Previously considered as a component of transcriptional noise, long noncoding RNAs (lncRNAs) were neglected as a therapeutic target, however, recently increasing evidence has shown that lncRNAs can participate in numerous biological processes involved in genetic regulation including epigenetic, transcriptional, and post-transcriptional regulation. In this review, we discuss the fundamental functions of lncRNAs at different regulatory levels and their roles in metabolic balance. Typical examples are introduced to illustrate their diverse molecular mechanisms.

Rapid immobilization of simulated radioactive soil waste by microwave sintering.

A rapid and efficient method is particularly necessary in the timely disposal of seriously radioactive contaminated soil. In this paper, a series of simulated radioactive soil waste containing different contents of neodymium oxide (3-25wt.%) has been successfully vitrified by microwave sintering at 1300°C for 30min.

Multi-elements determination in medical and edible Alpinia oxyphylla and Morinda officinalis and their decoctions by ICP-MS.

Contents of twenty elements (Mg, K, Ca, Na, Fe, Al, Zn, Ba, Mn, Cu, Mo, Cr, Ni, As, Se, Cd, Hg, Tl, Pb and V) in two medical and edible plant species, Alpinia oxyphylla and Morinda officinalis were simultaneously determined by inductively coupled plasma-mass spectrometry (ICP-MS) method after microwave digestion with HNO-HO (6:1, v/v) as the digestion solvent. Certified standard reference material Poplar leaf was used to assess the accuracy of the method. The greatest contents of Mg, K, Ca, Al, Fe and Na were found in dried Alpinia oxyphylla and Morinda officinalis samples.

[Analysis of Risk Factors and Therapeutic Strategies for Relapse of Leukemia after Allogeneic Hematopoietic Stem Cell Transplantation].

Objective: To analyze the risk factors of patients with relapsed leukemia after allogeneic hematopoietic stem cell transplantation, and to explore the therapeutic strategies for recurrence.

Methods: The Cox proportional hazard regression model was used for univariate and multivariate analysis of transplantation-related index, a single center retrospective study of clinical data of 202 cases of leukemia received allo-HSCT from March 2004 to October 2014 had been conducted to screen the risk factors for recurrence after transplantation.

Results: In the leukemia patients received allo-HSCT, 68 cases relapsed.

Efficacy of pegaspargase in extra nodal natural killer/T-cell lymphoma nasal type: A case report from China.

Extranodal natural killer (NK)/T-cell lymphoma, nasal type, is a rare and highly aggressive disease with a grim prognosis. There is no known satisfactory treatment. The author herein to report one case of L-asparaginase extranodal NK/T-cell lymphoma primary treated with L-asparaginase methotrexate and dexamethasone.

Chemotherapy-associated hepatotoxicity in colorectal cancer.

Chemotherapy-associated hepatotoxicity in liver metastatic colorectal cancer is attracting more and more attention for clinicians. This hepatotoxicity heralds an increased risk of morbidity and mortality in patients with colorectal liver metastases, therefore it is important that clinicians have an adequate knowledge of the chemotherapy-associated hepatotoxicity.

Novel binding regioselectivity in the interpenetration of a non-symmetric axle into a non-symmetric pillar[5]arene wheel.

We describe the regioselective complexation of a non-symmetric 5-bromovaleronitrile axle by a non-symmetric pillar[5]arene bearing different alkyl (methyl and pentyl) rims, forming an oriented interpenetrated complex with the directionality of CN@methyl rim and Br@pentyl rim.

Cervical metastasis of esophagogastric junction cancer.

As cervical metastases in esophagogastric junction cancer are extremely rare, the authors herein report a case. A 63-year-old woman presented with dysphagia since 6 months. Diagnostic endoscopy showed that the tumor was located at the esophagogastric junction and histopathological diagnosis of adenocarcinoma was offered.

Molecular selective binding of basic amino acids by a water-soluble pillar[5]arene.

Highly selective binding of basic amino acids, i.e. lysine, arginine, and histidine, by a negatively charged carboxylatopillar[5]arene (CP5A) is reported.

Selective and effective binding of pillar[5,6]arenes toward secondary ammonium salts with a weakly coordinating counteranion.

The selective and effective binding of secondary ammoniums with a weakly coordinating tetrakis[3,5-bis(trifluoromethyl)phenyl]borate (BArF) counteranion by per-ethylated pillar[5,6]arenes is reported. The construction of a first pillararene-based self-sorting system consisting of two wheels and two axles is also described.

Complexation of neutral 1,4-dihalobutanes with simple pillar[5]arenes that is dominated by dispersion forces.

The complexation of neutral 1,4-dihalobutanes with simple pillar[5]arenes was investigated. The results indicate the formation of interpenetrated complexes, where the dispersive interactions dominate the complex stability. Typically, 1,4-diiodobutane displays the strongest binding strength with ethylpillar[5]arene [K(a) = (1.

Highly effective binding of neutral dinitriles by simple pillar[5]arenes.

Highly effective binding of neutral dinitriles by simple alkyl-substituted pillar[5]arenes and the formation of interpenetrated geometries are reported. The resulting host-guest complexes represent one of the most efficient recognition motifs based on pillararenes.

Synthesis of pillar[5]arene dimers and their cooperative binding toward some neutral guests.

Three pillar[5]arene dimers, bridged by a flexible aliphatic chain (H1) or a relatively rigid phenylene unit (H2 and H3), were synthesized, with the possible synthetic strategies being discussed. The dimers could significantly enhance the binding affinities toward neutral model substrates in comparison with monomeric 1,4-dimethoxypillar[5]arene (H4) through the cooperative binding of two pillar[5]arene moieties. The molecular binding ability and selectivity are discussed from the viewpoints of the size/shape-fit concept and multiple recognition mechanism.

Complexation of 1,4-bis(pyridinium)butanes by negatively charged carboxylatopillar[5]arene.

The binding behavior of substituted 1,4-bis(pyridinium)butane derivatives (X-Py(CH(2))(4)Py-X, X = H, 2-methyl, 3-methyl, 4-methyl, 2,6-dimethyl, 4-pyridyl, and 4-COOEthyl) 1(2+)-7(2+), with negatively charged carboxylatopillar[5]arene (CP5A) has been comprehensively investigated by (1)H NMR and 2D ROESY and UV absorption and fluorescence spectroscopy in aqueous phosphate buffer solution (pH 7.2). The results indicated that the position of the substituents attached on pyridinium ring dramatically affects the association constants and binding modes.

[Study on quality changes of Radix Aconiti Lateralis Praeparata under different storage conditions].

Objective: To analyze the changes of the content of water, soluble protein, total alkaloids, polysaccharides of Radix Aconiti Lateralis Praeparata under different storage treatments.

Methods: The experiment was conducted in 4 kinds of storage methods, such as sack storage, sand storage, cold storage, and the natural heap as the control.

Results: During storage, the content of water, total alkaloids and polysaccharides tended to decline, while the content of soluble protein increased.