Expression and prognostic value of cell-cycle-associated genes in lung squamous cell carcinoma.

Background: Lung cancer continues to be a prevalent cause of cancer-related deaths worldwide, with lung squamous carcinoma (LUSC) being a significant subtype characterized by comparatively low survival rates. Extensive molecular studies on LUSC have been conducted; however, the clinical importance of cell-cycle-associated genes has rarely been examined. This study aimed to investigate the relationship between these genes and LUSC.

Bipolar Textile Composite Electrodes Enabling Flexible Tandem Solid-State Lithium Metal Batteries.

A majority of flexible and wearable electronics require high operational voltage that is conventionally achieved by serial connection of battery unit cells using external wires. However, this inevitably decreases the energy density of the battery module and may cause additional safety hazards. Herein, a bipolar textile composite electrode (BTCE) that enables internal tandem-stacking configuration to yield high-voltage (6 to 12 V class) solid-state lithium metal batteries (SSLMBs) is reported.

The supraclavicular approach in the management of cervicothoracic-junction benign neurogenic tumors: A real-world analysis.

Objectives: The study objectives were to evaluate the safety, feasibility, and risk of neurologic complications with the supraclavicular approach in the operative management of cervicothoracic-junction benign neurogenic tumors.

Methods: Between January 2012 and April 2023, 115 patients who underwent surgical resection for cervicothoracic-junction benign neurogenic tumors were retrospectively enrolled. Patients were divided into 3 groups based on the surgical approach: supraclavicular alone (Supraclav-Alone), n = 16; Transthoracic-Alone (video-assisted thoracoscopic surgery/Open), n = 87; and supraclavicular combined with transthoracic (Supraclav + video-assisted thoracoscopic surgery/open), n = 12.

Safety and efficacy of delayed completion lobectomy following wedge resection segmentectomy-a retrospective cohort study.

Background: Data regarding the safety and efficacy of delayed completion lobectomy (CL) following sublobar resections remain scant. We evaluated the technical difficulty and short-term outcomes of CL occurring at least 3 months following the anatomical segmentectomy or wedge resection.

Methods: Consecutive non-small cell lung cancer (NSCLC) patients who underwent a second resection within the same lobe at least 3 months after their initial resection from January 2013 to December 2019 at the Shanghai Pulmonary Hospital were retrospectively included.

Insight into Multiple Intermolecular Coordination of Composite Solid Electrolytes via Cryo-Electron Microscopy for High-Voltage All-Solid-State Lithium Metal Batteries.

Polymer/ceramic-based composite solid electrolytes (CSE) are promising candidates for all-solid-state lithium metal batteries (SLBs), benefiting from the combined mechanical robustness of polymeric electrolytes and the high ionic conductivity of ceramic electrolytes. However, the interfacial instability and poorly understood interphases of CSE hinder their application in high-voltage SLBs. Herein, a simple but effective CSE that stabilizes high-voltage SLBs by forming multiple intermolecular coordination interactions between polyester and ceramic electrolytes is discovered.

Efficacy evaluation of surgery combined with chemotherapy for stage IIIA small cell lung cancer patients: a retrospective analysis.

Background: The efficacy of surgery in combination of chemotherapy for stage IIIA small cell lung cancer (IIIA-SCLC) is controversial. The aim of the present study was to analyze the efficacy of surgery combined with chemotherapy, especially in the setting of neoadjuvant chemotherapy (NAC) followed by surgery for IIIA-SCLC.

Methods: Between 2004 and 2015, we reviewed 2,199 chemotherapy-treated stage IIIA (N1/2) SCLC cases in the Surveillance, Epidemiology, and End Results (SEER) database, and 32 NAC + intentional radical resection-treated, centrally-located IIIA-SCLC cases at Shanghai Pulmonary Hospital (SPH).

Bevacizumab-Laden Nanofibers Simulating an Antiangiogenic Niche to Improve the Submuscular Stability of Stem Cell Engineered Cartilage.

Bone marrow stem cells (BMSCs) engineered cartilage (BEC) is prone to endochondral ossification in a submuscular environment due to the process of vascular infiltration, which limits its application in repairing tracheal cartilage defects. Bevacizumab, an antitumor drug with pronounced antiangiogenic activity, is successfully laden into a poly(L-lactide-co-caprolactone) system to prepare bevacizumab-laden nanofiber (BevNF) characterized by 5% and 10% bevacizumab concentrations. The in vitro results reveal that a sustained release of bevacizumab can be realized from BevNF, exhibiting inhibitive cytotoxicity toward human umbilical vein endothelial cells whereas non-cytotoxicity toward BMSCs-induced chondrocytes.

Interpersonal Neural Synchronization Predicting Learning Outcomes From Teaching-Learning Interaction: A Meta-Analysis.

In school education, teaching-learning interaction is deemed as a core process in the classroom. The fundamental neural basis underlying teaching-learning interaction is proposed to be essential for tuning learning outcomes. However, the neural basis of this process as well as the relationship between the neural dynamics and the learning outcomes are largely unclear.

Propensity-matched Comparison of VATS Left Upper Trisegmentectomy and Lobectomy.

Background: This study aimed to investigate the oncologic outcomes of video-assisted thoracoscopic (VATS) left upper trisegmentectomy (LTS) vs left upper lobectomy (LUL) for patients presenting with stage I non-small cell lung cancer (NSCLC).

Methods: A retrospective analysis identified 1543 consecutive patients presenting to Shanghai Pulmonary Hospital (Shanghai, China) with NSCLC for VATS LTS or LUL from 2013 to 2017. After propensity-score matching for patient demographics and tumor characteristics, 273 pairs were identified.

Collaborative relationships in translational medical research among Chinese clinicians: an internet-based cross-sectional survey.

Background: This study aimed to explore the collaborative relationship in translational medical research from the perspective of clinicians in China. The findings are expected to help practitioners optimize and experience the greatest advantages of collaboration.

Methods: We conducted a national internet-based survey from July 29 to October 12, 2020.

The complete chloroplast genome of var. .

var. is one of the most important wild banana species native to China which has huge potential breeding value by its cold tolerance and disease resistance. In this study, we first reported the complete chloroplast genome of var.

The complete chloroplast genome of .

N.W. Simmonds is one of the most important wild banana species native to Borneo.

Coating of LiPS Electrolyte on CuCoS/Graphene Nanocomposite as a High-Performance Cathode for All-Solid-State Lithium Batteries.

A cathode material, CuCoS/graphene@10%LiPS, is reported for all-solid-state lithium batteries with high performance. The electrical conductivity of CuCoS is improved by compounding with graphene. Meanwhile, LiPS electrolyte is coated on the surface of CuCoS/graphene nanosheets to build an intimate contact interface between the solid electrolyte and the electrode effectively, facilitating lithium-ion conduction.

CoS@LiPS Hexagonal Platelets as Cathodes with Superior Interfacial Contact for All-Solid-State Lithium Batteries.

Poor solid-solid contact between an electrode and solid electrolyte is a great challenge for all-solid-state lithium batteries (ASSLBs) which results in limited ion transport and eventually leads to rapid capacity fading. Two-dimensional (2D) materials have incomparable advantage in the construction of the desired interface because of their flat surface and large specific surface area. In order to realize intimate interfacial contact and superior ion transport, monodisperse 2D CoS hexagonal platelets as cathodes for all ASSLBs are synthesized through a series of topological reactions followed with in situ coating of tiny LiPS using a liquid-phase method.

Si/a-C Nanocomposites with a Multiple Buffer Structure via One-Step Magnetron Sputtering for Ultrahigh-Stability Lithium-Ion Battery Anodes.

Large volume expansion and serious pulverization of silicon are two major challenges for Si-based anode batteries. Herein, a high-mass-load (3.0 g cm) silicon-doped amorphous carbon (Si/a-C) nanocomposite with a hierarchical buffer structure is prepared by one-step magnetron sputtering.

Microbial Community Diversity Within Sediments from Two Geographically Separated Hadal Trenches.

Hadal ocean sediments, found at sites deeper than 6,000 m water depth, are thought to contain microbial communities distinct from those at shallower depths due to high hydrostatic pressures and higher abundances of organic matter. These communities may also differ from one other as a result of geographical isolation. Here we compare microbial community composition in surficial sediments of two hadal environments-the Mariana and Kermadec trenches-to evaluate microbial biogeography at hadal depths.

Nanoscaled NaPS Solid Electrolyte for All-Solid-State FeS/Na Batteries with Ultrahigh Initial Coulombic Efficiency of 95% and Excellent Cyclic Performances.

Nanosized NaPS solid electrolyte with an ionic conductivity of 8.44 × 10 S cm at room temperature is synthesized by a liquid-phase reaction. The resultant all-solid-state FeS/NaPS/Na batteries show an extraordinary high initial Coulombic efficiency of 95% and demonstrate high energy density of 611 Wh kg at current density of 20 mA g at room temperature.

Core-Shell FeS@NaPSSe Nanorods for Room Temperature All-Solid-State Sodium Batteries with High Energy Density.

High ionic conductivity electrolyte and intimate interfacial contact are crucial factors to realize high-performance all-solid-state sodium batteries. NaPSSe electrolyte with reduced particle size of 500 nm is first synthesized by a simple liquid-phase method and exhibits a high ionic conductivity of 1.21 × 10 S cm, which is comparable with that synthesized with a solid-state reaction.

Highly Crystalline Layered VS Nanosheets for All-Solid-State Lithium Batteries with Enhanced Electrochemical Performances.

All-solid-state lithium batteries employing inorganic solid electrolytes have been regarded as an ultimate solution to safety issues because of their features of no leakage as well as incombustibility and they are expected to achieve higher energy densities owing to their simplified structure. Two-dimensional transition-metal dichalcogenides exhibit a great potential in energy storage devices because of their unique physical and chemical characteristics. In this work, 50 nm thick highly crystalline layered VS (hc-VS) nanosheets are prepared by a solvothermal method, and their electrochemical performances are evaluated in Li/75% LiS-24% PS-1% PO/LiGePS/hc-VS all-solid-state lithium batteries.

Interface Re-Engineering of LiGePS Electrolyte and Lithium anode for All-Solid-State Lithium Batteries with Ultralong Cycle Life.

An ingenious interface re-engineering strategy was applied to in situ prepare a manipulated LiHPO protective layer on the surface of Li anode for circumventing the intrinsic chemical stability issues of LiGePS (LGPS) to Li metal, specifically the migration of mixed ionic-electronic reactants to the inner of LGPS, and the kinetically sluggish reactions in the interface. As consequence, the stability of LGPS with Li metal increased substantially and the cycling of symmetric Li/Li cell showed that the polarization voltage could keep relative stable for over 950 h at 0.1 mA cm within ±0.

Clinicopathological features of Chinese lung cancer patients with mutation.

Background: () gene was the major causative gene of lung cancer and also the specific treatment target. It is necessary to analyze the genotype and phenotype characters of patients.

Methods: We investigated 1,034 lung cancer patients in this study.

Proton enhanced dynamic battery chemistry for aprotic lithium-oxygen batteries.

Water contamination is generally considered to be detrimental to the performance of aprotic lithium-air batteries, whereas this view is challenged by recent contrasting observations. This has provoked a range of discussions on the role of water and its impact on batteries. In this work, a distinct battery chemistry that prevails in water-contaminated aprotic lithium-oxygen batteries is revealed.

High-Energy All-Solid-State Lithium Batteries with Ultralong Cycle Life.

High energy and power densities are the greatest challenge for all-solid-state lithium batteries due to the poor interfacial compatibility between electrodes and electrolytes as well as low lithium ion transfer kinetics in solid materials. Intimate contact at the cathode-solid electrolyte interface and high ionic conductivity of solid electrolyte are crucial to realizing high-performance all-solid-state lithium batteries. Here, we report a general interfacial architecture, i.

[Electromagnetic navigation interlocking intramedullary nail technology for treatment of femoral shaft fractures].

Objective: To explore the value of electromagnetic navigation interlocking intramedullary nail in the treatment of femoral shaft fracture.

Methods: Between July 2012 and October 2013, 53 cases of femoral shaft fracture were treated. There were 40 males and 13 females, aged 16-52 years (mean, 38.

Risk factors for major adverse events of video-assisted thoracic surgery lobectomy for lung cancer.

Aims: The purpose of this study was to identify the risk factors for major adverse events of VATS (Video-Assisted Thoracic Surgery) lobectomy for primary lung cancer.

Methods: 1806 Patients (1032 males, 57.1%) planned to undergo VATS lobectomy for stage IA-IIIA lung cancer from July 2007 to June 2012.