A Polymeric Hole Transporter with Dual-Interfacial Interactions Enables 25%-Efficiency Blade-Coated Perovskite Solar Cells.

Self-assembly monolayer (SAM) hole transporters, consisting of anchoring, spacer, and terminal groups, have played a significant role in the development of inverted perovskite solar cells (PSCs). However, the weak interaction between perovskite and hydrophobic terminal group of SAMs limits surface wettability and interface stability. To address this issue, two novel hole transporters (named DBPP and Poly-DBPP) with centrosymmetric biphosphonic acid groups are developed.

Regulating Intermolecular Interactions and Film Formation Kinetics for Record Efficiency in Difluorobenzothiadizole-Based Organic Solar Cells.

The difluorobenzothiadizole (ffBT) unit is one of the most classic electron-accepting building blocks used to construct D-A copolymers for applications in organic solar cells (OSCs). Historically, ffBT-based polymers have achieved record power conversion efficiencies (PCEs) in fullerene-based OSCs owing to their strong temperature-dependent aggregation (TDA) characteristics. However, their excessive miscibility and rapid aggregation kinetics during film formation have hindered their performance with state-of-the-art non-fullerene acceptors (NFAs).

Vim-PSA Double-Target DBS for the Treatment of Holmes Tremor Secondary to Brainstem Hemorrhage: A Case Report.

We report the case of a 53-year-old man who was diagnosed with Holmes tremor and underwent deep brain stimulation of the ventro-intermediate thalamic nucleus and posterior subthalamic area. We assessed the patients' tremor with the Fahn-Tolosa-Marin Tremor Rating Scale at 1, 3, 6, 12 and 24 months after deep brain stimulation. Deep brain stimulation relieved the patient's tremor during the 24-month follow-up period.

Association between mixed metal exposure and stroke risk in Shanxi Province: a case-control study.

Background: Stroke is the second leading cause of death for all human beings and poses a serious threat to human health. Environmental exposure to a mixture of metals may be associated with the occurrence and development of stroke, but the evidence in the Chinese population is not yet conclusive.

Objectives: This study evaluated the association between stroke risk and 13 metals METHODS: Metal concentrations in whole blood samples from 100 stroke cases and 100 controls were measured by ICP-MS.

HO Photosynthesis from HO and O under Weak Light by Carbon Nitrides with the Piezoelectric Effect.

Driven by the essential need of a green, safe, and low-cost approach to producing HO, a highly valuable multifunctional chemical, artificial photosynthesis emerges as a promising avenue. However, current catalyst systems remain challenging, due to the need of high-density sunlight, poor selectivity and activity, or/and unfavorable thermodynamics. Here, we reported that an indirect 2e water oxidation reaction (WOR) in photocatalytic HO production was unusually activated by CN with piezoelectric effects.

Dynamics of simplicial SEIRS epidemic model: global asymptotic stability and neural Lyapunov functions.

The transmission of infectious diseases on a particular network is ubiquitous in the physical world. Here, we investigate the transmission mechanism of infectious diseases with an incubation period using a networked compartment model that contains simplicial interactions, a typical high-order structure. We establish a simplicial SEIRS model and find that the proportion of infected individuals in equilibrium increases due to the many-body connections, regardless of the type of connections used.

Efficient and Stable Air-Processed Organic Solar Cells Enabled by an Antioxidant Additive.

Current high-efficiency organic solar cells (OSCs) are generally fabricated in an inert atmosphere that limits their real-world scalable manufacturing, while the efficiencies of air-processed OSCs lag far behind. The impacts of ambient factors on solar cell fabrication remain unclear. In this work, the effects of ambient factors on cell fabrication are systematically investigated, and it is unveiled that the oxidation and doping of organic light absorbers are the dominant reasons causing cell degradation when fabricated in air.

Synthesis and modification mechanism of vanadium oxide coated LiFePOcathode materials with excellent electrochemical performance.

In an era of rapid industrial development, such that the demand for energy is increasing daily, lithium-ion batteries are playing a dominant role in energy storage devices due to their high safety and low cost. However, it is still a challenge for the preparation of advanced cathodes, which can determine the battery performance, with stable structures and fast diffusion of Li. This is especially the case for lithium iron phosphate (LFP), a cathode material with severe limitations due to its low conductive efficiency.

Inflammatory bowel disease and risk of Parkinson's disease: evidence from a meta-analysis of 14 studies involving more than 13.4 million individuals.

Background: The relationship between inflammatory bowel disease (IBD) and the risk of Parkinson's Disease (PD) has been investigated in several epidemiological studies. However, the results of these studies were inconclusive and inconsistent. We evaluated the potential relationship between IBD and PD risk by a meta-analysis.

Molecular assembly of carbon nitride-based composite membranes for photocatalytic sterilization and wound healing.

Polymeric carbon nitride (pCN) has attracted increasing interest as a metal-free photocatalyst because of its high efficiency in reactive oxygen species (ROS) generation. However, due to poor solubility, compounding pCN at the molecular level into more advanced nanocomposites remains a challenge. Herein, we report the dissolution of pCN in polyphosphoric acid (PPA) for the first time and fluid-phase assembly with carbon nanotubes (CNTs) into a flexible free-standing membrane.

Spinal subdural hematoma in a patient with immune thrombocytopenic purpura following microvascular decompression: a rare case report.

This article reports a case of spontaneous spinal subdural hematoma (SSDH) after brain surgery in a patient with immune thrombocytopenic purpura (ITP), reviews the relevant literature, and discusses the etiology, pathogenesis, and clinical features of SSDH in patients with ITP. A male patient in his early 50 s with an 8-year history of ITP and suffering from coexistent hemifacial spasm and trigeminal neuralgia underwent microvascular decompression in our department. His preoperative corrected platelet count was within the normal range.

A homozygous -associated juvenile Parkinson's disease with pregnancy in China.

Background: Although Parkinson's disease (PD) is the second most common neurodegenerative disorder, pregnancy in patients with PD is a relatively rare occurrence because the most common age of onset of PD is beyond the childbearing age, except in patients with Young-Onset PD (YOPD) caused by parkin RBR E3 ubiquitin protein ligase () mutations.

Case: In this study, we report the case of a 30-year-old Chinese woman who was affected by -associated YOPD and was treated with levodopa/benserazide during pregnancy. She gave birth to a healthy baby boy with an Apgar score of 9 through an uncomplicated vaginal delivery.

Fe-doped VOlayered nanowire cathode material with high lithium storage performance.

As a lithium-ion battery cathode material with high theoretical capacity, the application of VOis limited by its unstable structure and low intrinsic conductivity. In this paper, we report a Fe doped VOnanowire with a layered structure of 200-300 nm diameter prepared by electrostatic spinning technique. The 3Fe-VOelectrode exhibited a superb capacity of 436.

Effects of Hemp Sanitary Pads on the Vaginal Microecology.

Objective: To evaluate the effect of hemp cotton sanitary pads on the vaginal microecology.

Methods: A randomized controlled field trial was used to recruit 1002 community-based women of childbearing age. The women were randomly divided into experimental and control groups.

Extended Conjugation Tuning Carbon Nitride for Non-sacrificial H O Photosynthesis and Hypoxic Tumor Therapy.

Artificial photocatalysis offers a clean approach for producing H O . However, the poor selectivity and activity of H O production hamper traditional industrial applications and emerging photodynamic therapy (PDT)/chemodynamic therapy (CDT). Herein, we report a C N photocatalyst with a conjugated C=N linkage for selective and efficient non-sacrificial H O production in both normoxic and hypoxic systems.

Complex Dynamics of Noise-Perturbed Excitatory-Inhibitory Neural Networks With Intra-Correlative and Inter-Independent Connections.

Real neural system usually contains two types of neurons, i.e., excitatory neurons and inhibitory ones.

Use of oral glucose tolerance testing and HbA1c at 6-14 gestational weeks to predict gestational diabetes mellitus in high-risk women.

Purpose: To study the prediction of gestational diabetes mellitus (GDM) in high-risk pregnant women by testing fasting blood glucose, 1-h(1hPG) and 2-h plasma glucose (2hPG) after an oral glucose tolerance test, and glycated hemoglobin (HbA1c) in early pregnancy (6-14 weeks).

Methods: We recruited 1311 pregnant women at high risk for diabetes from the Obstetrics Clinic of Daxing District People's Hospital between June 2017 and December 2019. The tests performed during the first trimester included fasting blood glucose (FPG), HbA1c, and 75-g oral glucose tolerance test (OGTT) with 1hPG and 2hPG.

Empirical antibiotic treatment strategies for community-acquired pneumonia: a network meta-analysis.

Objectives: This network meta-analysis aimed to compare the efficacy and safety of fluoroquinolone (FQ) monotherapy, β-lactam (BL) monotherapy and β-lactam/macrolide (BL-M) combination therapy in hospitalized patients with community-acquired pneumonia (CAP).

Methods: Pubmed, Embase and the Cochrane Library were searched for randomized controlled trials (RCTs) comparing FQ monotherapy, BL monotherapy and BL-M combination therapy up to July 2021. The outcomes of interest included all-cause mortality, clinical success, microbiological success and drug-related adverse events.

Serum RANKL levels in Chinese patients with ankylosing spondylitis: a meta-analysis.

Objective: We aimed to determine the association between serum receptor activator of nuclear factor-kappa B ligand (sRANKL) levels and ankylosing spondylitis (AS) in Chinese patients.

Methods: The PubMed, Cochrane Library, Embase, Chinese Biomedical Database, Web of Science, China National Knowledge Infrastructure, VIP, and Wan Fang databases were searched for studies conducted before October 1, 2020, without language restrictions. STATA version 12.

Correlation of exosomal microRNA clusters with bone metastasis in non-small cell lung cancer.

20-40% of lung cancer patients develop bone metastasis (BM) with significantly decreased overall survival. Currently, BM is mainly diagnosed by computerized tomography (CT) scan or magnetic resonance imaging (MRI) when symptom develops. Novel biomarkers with higher prediction value of BM are needed.

Correlation between osteoarthritis and monocyte chemotactic protein-1 expression: a meta-analysis.

Objective: We evaluated the association between monocyte chemotactic protein-1 (MCP-1) and osteoarthritis.

Methods: We searched PubMed, Cochrane Library, Embase, Web of Science, China National Knowledge Infrastructure (CNKI), VIP (Chinese database), and Wan Fang (Chinese database) (before May 10, 2020), with no language limitations. STATA version 12.

Immunoglobulin G4-related hypertrophic pachymeningitis with spinal cord compression: A case report.

IgG4-related disease (IgG4-RD) is a recently recognized inflammatory condition that can be found in many organs. However, spinal involvement is rare and has been described only in case reports and series. Here, we report a rare case of spinal IgG4-RD that resulted in hypertrophic pachymeningitis with spinal cord compression.

Green synthesis of fluorescent carbon dots using chloroplast dispersions as precursors and application for Fe ion sensing.

Water-soluble carbon dots (CDs) were synthesized using a one-step hydrothermal treatment of chloroplast dispersions extracted from fresh leaves as a green carbon source. The CD solution showed an emission peak centred at 445 nm when excited at 300 nm. The synthesized CDs were uniform and monodispersed with an average size of 5.

Correlation of plasma exosomal microRNAs with the efficacy of immunotherapy in wild-type advanced non-small cell lung cancer.

Background: Immunotherapy has become an important treatment option for patients with advanced non-small cell lung cancer (NSCLC). At present, none of these existing biomarkers can effectively stratify true responders and there is an urgent need for identifying novel biomarkers. Exosomes derived from the serum of patients with cancer have been proven to be reliable markers for cancer diagnosis.

Green and Orange Fluorescent Carbon Dots for Detecting Oral Cancer by Staining Tissue Sections.

By using ethylenediamine (ED) with nitric acid (NA) and formic acid (FA) as raw materials, two types of new carbon dots (CDs) were prepared using microwave method. The as-prepared CDs showed excellent water solubility and photoluminescence properties. The optimum excitation wavelength and emission wavelength of new CDs were at 430 nm and 500 nm (for CDs fabricated with ED and NA) and at 480 nm and 570 nm (for CDs synthesized with ED and FA), respectively.