Causal Effects of Valine on Ovarian Cancer: A Bidirectional Mendelian Randomization Analysis.

Background: Ovarian cancer is a lethal female cancer with a rising incidence that is often diagnosed late due to a lack of symptoms, affecting survival and quality of life. Studies suggest that dietary factors, especially the levels of branched-chain amino acids such as valine, may influence its development. While valine is essential for metabolism, its specific role in ovarian cancer remains unclear, necessitating further research.

Machine-Learning-Based Predictive Model for Bothersome Stress Urinary Incontinence Among Parous Women in Southeastern China.

Introduction And Hypothesis: Accurate identification of female populations at high risk for urinary incontinence (UI) and early intervention are potentially effective initiatives to reduce the prevalence of UI. We aimed to apply machine-learning techniques to establish, internally validate, and provide interpretable risk assessment tools.

Methods: Data from a cross-sectional epidemiological survey of female urinary incontinence conducted in 2022 were used.

Laparoscopic lateral suspension with mesh for severe anterior and apical pelvic organ prolapse: an observational cohort study for safety and efficacy at 2-year follow-up.

Purpose: This study aimed to investigate the clinical safety and efficacy of laparoscopic lateral suspension (LLS) with mesh in the treatment of severe anterior and apical pelvic organ prolapse (POP) Chinese women with a 2-year follow-up.

Methods: We conducted an observational cohort study. Sixty patients who presented apical (uterovaginal or vault) and anterior prolapse at stage 3 or higher were enrolled.

Incidence, Risk Factors, and Correlation with Caprini Score of Deep Vein Thrombosis After Colpocleisis with/without Concomitant Hysterectomy for Pelvic Organ Prolapse in Elderly Women.

Introduction And Hypothesis: The objective was to investigate the incidence and risk factors of lower extremity deep vein thrombosis (DVT) in elderly women undergoing colpocleisis for pelvic organ prolapse and to evaluate the predictive efficacy of the Caprini scores.

Methods: Data from patients who underwent colpocleisis from August 2019 to April 2024 were retrospectively analyzed. The primary endpoint was DVT detected by ultrasonography within 7 days of surgery.

Prediction Model for Delayed Behavior of Early Ambulation After Surgery for Varicose Veins of the Lower Extremity: A Prospective Case-Control Study.

Objective: To analyze influencing factors and establish a prediction model for delayed behavior of early ambulation after surgery for varicose veins of the lower extremity (VVLE).

Design: A prospective case-control study.

Setting: Patients with VVLE were recruited from 2 local hospitals.

Development and Validation of a Risk Prediction Model for Female Stress Urinary Incontinence in Rural Fujian, China.

Purpose: With China's rapidly aging population and the rising proportion of obese people, an increase in the number of women suffering from urinary incontinence (UI) is to be expected. In order to identify high-risk groups before leakage occurs, we aimed to develop and validate a model to predict the risk of stress UI (SUI) in rural women.

Patients And Methods: This study included women aged 20-70 years in rural Fujian who participated in an epidemiologic survey of female UI conducted between June and October 2022.

Migration and transformation of phosphorus and toxic metals during sludge incineration with Ca additives.

The recycling and utilization of phosphorus resources in sludge is becoming increasingly important. In this study, we compared the conversion of phosphorus and toxic metal passivation effects of different Ca additives under oxygen-rich combustion conditions and elucidated their specific mechanisms of action. The experimental results indicated that four Ca-based additives improved the recovery rate of total phosphorus, and promoted the generation of stable apatite phosphorus (AP).

Towards biomass production and wastewater treatment by enhancing the microalgae-based nutrients recovery from liquid digestate in an innovative photobioreactor integrated with dialysis bag.

Microalgae-based nutrients recovery from liquid anaerobic digestate of swine manure has been a hotspot in recent decades. Nevertheless, in consideration of the high NH-N content and poor light penetrability exhibited by the original liquid digestate, uneconomical pretreatment on liquid digestate including centrifugation and dilution are indispensable before microalgae cells inoculation. Herein, aiming at eliminating the energy-intensive and freshwater-consuming pretreatment on liquid digestate and enhancing microalgae growth, the dialysis bag which permits nutrients transferring across its wall surface whereas retains almost all matters characterized by impeding light transmission within the raw liquid digestate was integrated into a column photobioreactor (DB-PBR).

A nomogram model can predict the risk of venous thromboembolism in postoperative patients with gynecological malignancies.

Objective: To explore independent factors influencing the risk of lower extremity deep vein thrombosis during the postoperative period in patients with gynecological malignancies by constructing a predictive model.

Methods: In our study, we collected 573 patients with gynecological malignancies in the postoperative period between September 2016 and September 2020, who were divided into a modeling (n = 402) and verification group (n = 171) according to a ratio of 7:3. Univariate and multivariate regression analyses were used to determine independent factors influencing deep vein thrombosis (DVT).

Enhancing CO photo-biochemical conversion in a newly-designed attached photobioreactor characterized by stacked horizontal planar waveguide modules.

Aiming at alleviating the adverse effects on attached microalgae biofilm growth caused by heterogeneous spatial light distributions within the attached cultivation photobioreactors (PBRs), an innovative PBR integrated with stacked horizontal planar waveguide modules (SHPW-PBR) was proposed in this work. Different from the conventional PBR, the emergent light from the external LED light bars were guided and evenly redistributed within the SHPW-PBR by the planar waveguides and hence provided light energy for microalgae cells photoautotrophic growth. In comparison with the control PBR, the average light intensity illuminating the attached Chlorella vulgaris biofilm in the SHPW-PBR was elevated by 204.

Two-stage nomogram models in mid-gestation for predicting the risk of spontaneous preterm birth in twin pregnancy.

Purpose: This study aimed to develop two-stage nomogram models to predict individual risk of preterm birth at < 34 weeks of gestation in twin pregnancies by incorporating clinical characteristics at mid-gestation.

Methods: We used a case-control study design of women with twin pregnancies followed up in a tertiary medical centre from January 2018 to March 2019. Maternal demographic characteristics and transvaginal cervical length data were extracted.

Physical examination-indicated cerclage in twin pregnancy: a retrospective cohort study.

Purpose: This study aimed to evaluate the efficacy of physical examination-indicated cerclage in twin pregnancies and compare it with those that received conservative management.

Methods: We used a retrospective cohort study design of asymptomatic twin pregnancies identified with physical examination indications at 14-26 weeks from 2015 through 2019 at Fujian Maternity and Child Health Hospital. The primary outcomes were gestational age (GA) at delivery and the incidence of spontaneous preterm birth (SPTB) at < 34 weeks, < 32 weeks, < 28 weeks, and < 24 weeks.

Association of the vaginal microbiota with pregnancy outcomes in Chinese women after cervical cerclage.

Research Question: The study aimed to investigate the relationship between risk factors associated with vaginal microbiota and outcomes of cervical cerclage.

Design: A retrospective cohort study of singleton pregnancies with cervical cerclage was conducted. Before cerclage, participants underwent a vaginal microbiota assay, including morphological examination and functional vaginal microecological analysis using a vaginitis multi-test kit.

Catalytic transfer hydrogenolysis of lignin into monophenols over platinum-rhenium supported on titanium dioxide using isopropanol as in situ hydrogen source.

Using isopropanol as an in situ hydrogen donor, catalytic transfer hydrogenolysis of lignin into monomeric phenols was studied at mild conditions. The performance of catalysts and the effects of H, temperature, and time on depolymerization of acid extracted birch lignin (ABL) were extensively examined. Platinum-rhenium supported on titanium dioxide (PtRe/TiO) exhibited much higher activity on disrupting CO bonds than Pd/C, HZSM-5, Pt/TiO, and Re/TiO.

Physicochemical characteristics and pyrolysis performance of corn stalk torrefied in aqueous ammonia by microwave heating.

The physicochemical characteristics and pyrolysis performance of corn stalk (CS) torrefied in water and aqueous ammonia by microwave heating were investigated. Physicochemical characterization revealed that both microwave water torrefied CS (MCS) and microwave ammonia torrefied CS (MACS) showed low hemicellulose content, disrupted macrostructure, improved porous properties, and low ash content. MACS exhibited a significantly lower crystallinity degree of 44.

Solvolysis kinetics of three components of biomass using polyhydric alcohols as solvents.

The solvolysis behavior and reaction kinetics of the three components of biomass (cellulose, hemicelluloses and lignin) liquefied in polyhydric alcohols (PEG 400 or glycerol) were investigated in this paper. Three stages were observed during the solvolysis process and the main degradation stage could be further divided into two zones. The influences of solvents on the liquefaction process of three main components were compared.

Kinetic and product composition study on the cellulose liquefaction in polyhydric alcohols.

The liquefaction process of cellulose in polyhydric alcohols (PEG 400 and glycerol) was studied by TG-FTIR. Three stages were observed during the solvolysis process and the main liquefaction stage could be further divided into two zones. The differences of liquefaction behavior of cellulose in the two solvents were compared, and the functional groups of volatiles produced by solvolysis were also evaluated.

Circularly polarized luminescence and tuning chromaticity of Eu(III)-grafting chiral polymer based on variable position of the substitution.

The novel chiral conjugated polymers P-1 and P-3 are prepared from the monomers S-M-2 and S-M-3 with (R,R)-1,2-aminocyclohexane (M-1) via a nucleophilic addition-elimination reaction, respectively. The Eu(III)-grafting chiral polymers P-2 and P-4 could be obtained by direct coordination reaction of Eu(TTA)3 ·2H2 O with P-1 and P-3, respectively. Photoexcitation of P-2 produces pink color emission as a result of the combination of partial blue self-emission chromophore of P-1 along with the red color from the Eu(TTA)3 moiety, whereas P-4 shows the exclusively red color emission from the Eu(III) ((5) D0 →(7) F2 ) transition due to almost complete excitation energy transfer from the macromolecular chain to the Eu(TTA)3 moiety.

Chiral sensing for induced circularly polarized luminescence using an Eu(III)-containing polymer and D- or L-proline.

An Eu(III)-containing polymer can exhibit intense induced circularly polarized luminescence (CPL) in the presence of proline. In addition, the optical anisotropy factor (g(lum)) of the polymer for (5)D0 → (7)F1/(7)F2 transition was much higher than that of a single model molecule, which reveals the amplification effect of CPL arising from the conjugated polymer structure.

L-Proline promoted fluorescent sensor for Mg2+ detection in a multicomponent sensory system.

Mg(2+) can lead to the fluorescence enhancement of a dye molecule as high as 47.3-fold while L-proline acts as a promoter in this multicomponent sensory system. The fluorescence color could be easily detected by the naked eye under a UV-lamp.

Na+ triggered fluorescence sensors for Mg2+ detection based on a coumarin salen moiety.

Two coumarin salen-based sensors CS1 and CS2 can exhibit a pronounced fluorescence enhancement response toward Mg(2+) as high as 36-fold (CS1) and 111-fold (CS2) in the presence of Na(+) as a synergic trigger. More importantly, the fluorescent color of CS1 was bright green instead of weak yellow after the addition of Mg(2+) and Na(+) together, which can be easily detected by the naked eye.