CircZNF609/miR-324-5p/voltage-dependent anion channel 1 axis promotes malignant progression of ovarian cancer cells.

The dysregulation of circular RNAs (circRNAs) has been associated with OC development and progression. This study investigated the role of circZNF609 in ovarian cancer (OC) by analyzing its impact on cell proliferation, migration, and invasion. Initially, the study assessed the expression of circZNF609 in OC tissues and adjacent normal tissues.

MiR-155-5p promotes fibroblast cell proliferation and inhibits FOXO signaling pathway in vulvar lichen sclerosis by targeting FOXO3 and CDKN1B.

Vulvar lichen sclerosis (VLS) is a chronic inflammatory skin disorder. Evidence is accumulating that microRNAs (miRNAs) exert crucial roles in initiation and development of a wide range of human diseases. MiR-155-5p has been frequently reported to be implicated in the tumorigenesis and progression of multiple types of cancers, however, its biological role in VLS remains unclear.

[Study on the effect of di-(2-ethylhexyl) phthalate on pregnant rats and the protection of zinc against it in pregnancy].

Objective: To investigate the effect of di-(2-ethylhexyl) phthalate (DEHP) on pregnant rat and the protection of zinc.

Methods: Fifty rats were randomized equally into 5 groups consisting of blank (given 1 ml 0.9% sodium chloride), corn oil (given 1 ml corn oil), zinc (given 1 ml zinc gluconate including 1.