Publications by authors named "Xiaowa Gao"
Rapid endothelialization and functional recovery are considered as promising methods to extend the long-term effectiveness of cardiovascular implant materials. LOX-1 participates in the initiation and development of atherosclerosis and is highly expressed in a variety of cells involved in atherosclerosis, hence it is feasible to accelerate the recovery of endothelial function and inhibit the development of existing plaques by regulating LOX-1. Herein, the surface is modified with Poly I, a LOX-1 inhibitor, using rich amino dendritic macromolecules (PAMAM) as the linker coating, to against the pathological microenvironment.
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- * A newly developed superhydrophobic film combines various materials to provide non-adhesion, antibacterial, and self-cleaning properties while maintaining blood compatibility and excellent anticoagulant performance even after prolonged exposure to fluids.
- * The film also releases HS gas when exposed to acidic conditions, which enhances the healing of endothelial cells and prevents toxic zinc ion release, suggesting its potential for long-term applications in medical devices.