Publications by authors named "Xiaotan Yuan"

The composition of (Tai-Zi-Shen, TZS) is greatly influenced by the growing area of the plants, making it significant to distinguish the origins of TZS. However, traditional methods for TZS origin identification are time-consuming, laborious, and destructive. To address this, two or three TZS accessions were selected from four different regions of China, with each of these resources including distinct quality grades of TZS samples.

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Article Synopsis
  • Tuberculosis (TB) is caused by the bacteria Mycobacterium tuberculosis (Mtb), which primarily infects macrophages, leading to programmed cell death known as pyroptosis.
  • The study investigates how endoplasmic reticulum stress (ERS) influences NLRP3 inflammasome activation and pyroptosis in THP-1 macrophages infected with BCG, a vaccine strain of Mtb.
  • Results indicate that BCG infection notably increases ERS, activates the NLRP3 inflammasome, and triggers pyroptosis in macrophages, with inhibitors like TUDCA and MCC950 effectively reducing these effects.
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Objective To investigate the effect of Wnt5a on autophagy in KGN human granulosa cells. Methods KGN human granulosa cells were treated with DMSO (control group), recombinant Wnt5a protein (rWnt5a), Wnt5a inhibitor IWP2 or BOX5, separately. The expression level of Wnt5a protein was detected by Western blot.

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