Publications by authors named "Xiaoran Hou"

Article Synopsis
  • Luteolin, a traditional Chinese medicine, shows promise as a treatment for hepatocellular carcinoma (HCC) by inhibiting tumor growth in H22 tumor-bearing mice.
  • The study found that luteolin boosts T-cell activation, enhances cytokine production, and maintains a high ratio of CD8 T lymphocytes in key areas like the spleen and tumor tissues.
  • By restoring the cytotoxicity of CD8 T lymphocytes and working effectively with PD-1 inhibitors, luteolin promotes a stronger anti-tumor immune response in H22 tumor models.
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Purpose: Approximately 20% to 30% of intracerebral hemorrhage (ICH) patients were reported to be on antiplatelet therapy (APT), and association between prior APT and prognosis was unclear. We aimed to clarify the impact of APT on the prognosis of ICH through an updated systematic review and meta-analysis, and to further compare the risk of single APT (SAPT) or dual APT (DAPT) prior to ICH as well as the risk associated with various antiplatelet drugs.

Methods: EMBASE, MEDLINE via Ovid SP and Web of Science were searched from inception of each database to November 4, 2023.

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Aims: Atorvastatin is a commonly used cholesterol-lowering drug that possesses non-canonical anti-inflammatory properties. However, the precise mechanism underlying its anti-inflammatory effects remains unclear.

Materials And Methods: The acute phase of ulcerative colitis (UC) was induced using a 5 % dextran sulfate sodium (DSS) solution for 7 consecutive days and administrated with atorvastatin (10 mg/kg) from day 3 to day 7.

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