Leonurine (Leo) has been found to have neuroprotective effects against cerebral ischemic injury. However, the exact molecular mechanism underlying its neuroprotective ability remains unclear. The aim of the present study was to investigate whether Leo could provide protection through the nitric oxide (NO)/nitric oxide synthase (NOS) pathway.
View Article and Find Full Text PDFThis paper presents a "structured" learning approach for the identification of continuous partial differential equation (PDE) models with both constant and spatial-varying coefficients. The identification problem of parametric PDEs can be formulated as an ℓ/ℓ-mixed optimization problem by explicitly using block structures. Block-sparsity is used to ensure parsimonious representations of parametric spatiotemporal dynamics.
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