Effect of moxibustion on the SIRT1/FOXO3a signaling pathway in ApoE mice with atherosclerosis.

Objectives: To observe the effects of moxibustion on blood lipid metabolism, pathological morphology of thoracic aorta, and the expression of silent information regulator 1 (SIRT1) and forkhead box transcription factor O3a (FOXO3a) in ApoE atherosclerosis (AS) mice, so as to explore the potential mechanism of moxibustion in preventing and treating AS.

Methods: Ten C57BL/6J mice were fed a normal diet as the control group, and 30 ApoE mice were fed a high-fat diet to establish the AS model, which were randomly divided into the model group, simvastatin group, and moxibustion group, with 10 mice in each group. From the first day of modeling, mice in the moxibustion group received mild moxibustion treatment at "Shenque"(CV8), "Yinlingquan"(SP9), bilateral "Neiguan"(PC6) and "Xuehai"(SP10) for 30 min per time；the mice in the simvastatin group were given simvastatin orally (2.

Effect of the arrangement of cavitation generation unit on the performance of an advanced rotational hydrodynamic cavitation reactor.

Hydrodynamic cavitation (HC) is widely considered a promising process intensification technology. The novel advanced rotational hydrodynamic cavitation reactors (ARHCRs), with considerably higher performance compared with traditional devices, have gained increasing attention of academic and industrial communities. The cavitation generation unit (CGU), located on the rotor and/or stator of an ARHCR, is utilized to generate cavitation and consequently, its geometrical structure is vital for the performance.

Copper-Catalyzed Intermolecular Cross-dehydrogenative C-N Coupling at Room Temperature via Remote Activating Group Enabled Radical Relay Strategy.

Employing -fluorobenzenesulfonimide (NFSI) as a nitrogen-centered radical (NCR) precursor, an intermolecular C(sp)-N coupling on heteroarenes or substituted benzenes with remote activated aniline derivatives via copper catalyzed N-N radical relay strategy at room temperature is developed. Good to excellent yields are acquired, and no ligand or additive is required. Reaction scope investigation and preliminary mechanistic studies demonstrate that the remote activating strategy and delicate control on the reactivities of active NCR species are essential to guarantee satisfactory chemo- and site-selectivity.

Integrative Histology-Genomic Analysis Predicts Hepatocellular Carcinoma Prognosis Using Deep Learning.

Cancer prognosis analysis is of essential interest in clinical practice. In order to explore the prognostic power of computational histopathology and genomics, this paper constructs a multi-modality prognostic model for survival prediction. We collected 346 patients diagnosed with hepatocellular carcinoma (HCC) from The Cancer Genome Atlas (TCGA), each patient has 1-3 whole slide images (WSIs) and an mRNA expression file.

Direct Benzylic C(sp)-O Coupling with Alcohol via Site-Selective C(sp)-H Cleavage at Room Temperature through a Remote Directing Group-Enabled Radical Relay Strategy.

Employing a low loading of the terminal oxidant, a remote directing group-enabled radical relay strategy for benzylic direct C(sp)-H alkoxylation with alcohols at room temperature is developed. Satisfactory site-selectivity, chemoselectivity, and reaction scope are achieved under simple and mild conditions, and no ligand or additive is required. Mechanistic studies, ready conversions of the directing group, and other benzylic functionalizations currently under development in our laboratory further indicate the promising potentials of this remote directing group-enabled radical relay strategy.

Influence of Fluid Food Viscosity on Internal Flow Characteristics of Conveying Pump.

A fluid food conveying pump is used to convey edible or nutritional fluids and semi-fluids (containing suspended soft and hard particles and with different viscosities), such as water, glycerin, yogurt, and juice concentrate. Since different fluid food have different viscosities, the internal flow characteristics and conveying performance of food conveying pump are greatly affected by viscosity. To obtain the influence law of fluid food viscosity on the internal flow characteristics of the pump, the internal flow characteristics of food conveying pump when conveying food of 4 different viscosities (water, glycerin, 67.

Research Status and Prospect for Vibration, Noise and Temperature Rise-Based Effect of Food Transport Pumps on the Characteristics of Liquid Foods.

In the field of food processing, the processing of liquid foods has always played an important role. Liquid foods have high requirements for the processing environment and equipment. As the core equipment in liquid foods processing, food transport pumps are widely used in liquid foods production, processing and transportation.

Visible-light enabled room-temperature dealkylative imidation of secondary and tertiary amines promoted by aerobic ruthenium catalysis.

Employing sulfonyl azide as a nitrogen donor, a visible-light-enabled aerobic dealkylative imidation of tertiary and secondary amines involving C(sp)-C(sp) bond cleavage with moderate to excellent yields at room temperature is described. It has been demonstrated that this imidation could take place spontaneously upon visible-light irradiation, and could be facilitated considerably by a ruthenium photocatalyst and oxygen. An alternative mechanism to the previous aerobic photoredox pathway has also been proposed.

Differentiation of ethanol-water clusters in Fenjiu by two-dimensional correlation fluorescence and Raman spectra.

The taste of different flavor liquor is multifarious, but the same brand liquor with different quality is truth. The essence of supramolecular ethanol-water clusters and their intrinsic structural differences in three kinds of Fenjiu are studied by two-dimensional correlation spectra (2D-COS) of fluorescence and Raman. The 2D-COS of fluorescence reveals the prominent emission peaks of three Fenjiu are apparently different.

Carbon Nanomaterials: Application and Prospects of Urban and Industrial Wastewater Pollution Treatment Based on Abrasion and Corrosion Resistance.

Environmental pollution as a result of urban and industrial wastewater has become an increasingly prominent issue. Rivers, lakes, and oceans that have become eutrophicated or polluted by suspended solids and hazardous substances in wastewater have endangered the environment. A root cause of this is the discharge of untreated urban and industrial wastewater into the ecosystem.

Experimental and numerical studies on the cavitation in an advanced rotational hydrodynamic cavitation reactor for water treatment.

Hydrodynamic cavitation (HC) has emerged as one of the most potential technologies for industrial-scale water treatment. The advanced rotational hydrodynamic cavitation reactors (ARHCRs) that appeared recently have shown their high effectiveness and economical efficiency compared with conventional devices. For the interaction-type ARHCRs where cavitation is generated from the interaction between the cavitation generation units (CGUs) located on the rotor and the stator, their flow field, cavitation generation mechanism, and interaction process are still not well defined.

Emulsion Template Method for the Fabrication of Gelatin-Based Scaffold with a Controllable Pore Structure.

The porous microstructure of scaffolds is an essential consideration for tissue engineering, which plays an important role for cell adhesion, migration, and proliferation. It is crucial to choose optimum pore sizes of scaffolds for the treatment of various damaged tissues. Therefore, the proper porosity is the significant factor that should be considered when designing tissue scaffolds.