Publications by authors named "Xiaoqi Dai"

The study aimed to investigate the impact of low-intensity pulsed ultrasound (LIPUS) on human urinary-derived stem cells (hUSCs) viability within three-dimensional (3D) cell-laden gelatin methacryloyl (GelMA) scaffolds. hUSCs were integrated into GelMA bio-inks at concentrations ranging from 2.5% to 10% w/v and then bioprinted using a volumetic-based method.

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Article Synopsis
  • - The study evaluated the effectiveness of nucleotide MALDI-TOF MS for diagnosing rifampicin resistance in drug-resistant tuberculosis (DR-TB) compared to the Xpert MTB/RIF method, revealing that MALDI-TOF MS had better performance metrics like sensitivity and accuracy.
  • - Conducted at Qingdao Chest Hospital, the research involved a retrospective analysis of 125 DR-TB patients, where results were validated using various testing methods including phenotypic drug susceptibility testing and Sanger sequencing.
  • - Findings indicated that certain factors, like chest pain and sensitivities to other TB drugs, were significantly associated with rifampicin resistance among the patients, highlighting potential areas for further investigation and treatment strategies in DR-TB management.
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Introduction: Emerging evidence indicates that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infected individuals are at an increased risk for co-infections. This retrospective study aims to expand the knowledge of associated factors of respiratory co-infection in SARS-CoV-2 positivity.

Methodology: A retrospective study was conducted to recruit fifty-five patients with laboratory-confirmed SARS-CoV-2 positivity.

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MicroRNAs (miRNAs) are novel tumor biomarkers owing to their important physiological functions in cell communication and the progression of multiple diseases. Due to the small molecular weight, short sequence length, and low concentration levels of miRNA, miRNA detection presents substantial challenges, requiring the advancement of more refined and sensitive techniques. There is an urgent demand for the development of a rapid, user-friendly, and sensitive miRNA analysis method.

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Article Synopsis
  • - The study evaluated knowledge, attitudes, and practices (KAP) regarding tuberculosis (TB) among 621 high school students in Qingdao, revealing a general high level of TB knowledge (82.09%) and practice (83.25%).
  • - Grade Three students demonstrated superior KAP scores compared to their lower-grade peers, and a significant number (78.42%) expressed fear of contracting TB, while 49.28% showed willingness to support TB patients.
  • - Findings suggest the need for a targeted TB education curriculum for younger students to improve awareness and prevention, utilizing platforms like social media and the internet for dissemination.
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Background: Hip fractures, commonly known as the "terminal fracture of life," frequently necessitate prompt surgical intervention and are accompanied by significant perioperative pain.

Objective: This investigation was performed to assess the impact of fascia iliaca compartment block (FICB) on heart rate variability during the perioperative period in elderly individuals with hip fractures.

Design: Single-center, randomized, controlled clinical trial.

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Optothermal nanotweezers have emerged as an innovative optical manipulation technique in the past decade, which revolutionized classical optical manipulation by efficiently capturing a broader range of nanoparticles. However, the optothermal temperature field was merely employed for in-situ manipulation of nanoparticles, its potential for identifying bio-nanoparticles remains largely untapped. Hence, based on the synergistic effect of optothermal manipulation and CRIPSR-based bio-detection, we developed CRISPR-powered optothermal nanotweezers (CRONT).

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Optical manipulation of various kinds of nanoparticles is vital in biomedical engineering. However, classical optical approaches demand higher laser power and are constrained by diffraction limits, necessitating tailored trapping schemes for specific nanoparticles. They lack a universal and biocompatible tool to manipulate nanoparticles of diverse sizes, charges, and materials.

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Phase interrogation surface plasmon resonance (P-SPR) biosensors have the highest sensitivity among different types of surface plasmon resonance (SPR) biosensors. However, P-SPR sensors have small dynamic detection range and complex device configuration. To solve these two problems, we designed a multi-channel P-SPR imaging (mcP-SPRi) sensing platform based on a common-path ellipsometry scheme.

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Surface plasmon resonance microscopy (SPRM) has been widely employed in biological fields because of its high spatial resolution and label-free detection modality. In this study, SPRM based on total internal reflection (TIR) is studied via a home-built SPRM system, and the principle of imaging of a single nanoparticle is analyzed as well. By designing a ring filter and combining it with the deconvolution algorithm in Fourier space, the parabolic tail of the nanoparticle image is removed, in which a spatial resolution of 248 nm is obtained.

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Objectives: As a closed gathering place, prison is the cradle of tuberculosis (TB) outbreak. Therefore, the analysis of the prevalence rate and risk factors of latent tuberculosis infection (LTBI) in prison will be a necessary measure to intervene in the spread of tuberculosis.

Methods: In this study, we consecutively recruited 506 adult prisoners in Qingdao to carry out this cross-sectional study.

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Objective: Myoclonus, a common complication during intravenous induction with etomidate, is bothersome to both anesthesiologists and patients. This study explored the preventive effect of pretreatment with propofol on etomidate-related myoclonus.

Methods: This was a prospective, double-blind, clinical, randomized controlled study.

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