Publications by authors named "Xiaoping Zhai"

To explore the effect of Mongolia Astragali Radix produced in Longxi of Gansu province in protecting cardiac and nephritic functions of patients of essential hypertension(EH) with metabolic syndrome(MetS). A total of two hundred and twenty-six EH patients with MetS aged above 18 were selected. Patients were randomly divided to control group(adopted conventional medical treatment), Astragali Radix group 1(added Astragali Radix capsules 10 g•d⁻¹ besides conventional medical treatment) and Astragali Radix group 2(added Astragali Radix capsules 5 g•d⁻¹ besides conventional medical treatment).

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Article Synopsis
  • The study investigates the biochemical activities of Chinese herbs used for treating male infertility, focusing on their effects on spermatogenesis and oxidative stress, which are significant factors in male infertility.
  • A total of 37 individual herbs and 7 herb decoctions were tested for endocrine activity and antioxidant properties, revealing various levels of anti-oestrogenic and antioxidant activity among the herbs.
  • The findings indicate that while individual herbs exhibited notable anti-oestrogenic effects and varying antioxidant strengths, the decoctions used clinically showed different activity profiles, primarily strong anti-oestrogenic responses without any androgenic or oestrogenic effects.
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Aim: To test the hypothesis that levels of sperm disomy fell significantly in six men treated by traditional Chinese medicine (TCM).

Methods: Fluorescence in situ hybridization (FISH) was done on the sperm heads of six men before and during treatment by TCM.

Results: There was a significant reduction in sperm disomy in all six men.

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Objective: To investigate the mutations of phenylalanine hydroxylase (PAH) gene in the cases of classical phenylketonuria (PKU).

Methods: The exons 3-12 of the PAH gene in 32 PKU patients from Inner Mongolia were studied by using PCR-single strand conformation polymorphism technique and DNA direct sequencing.

Results: Fourteen point mutations were identified.

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