Publications by authors named "Xiaopeng Si"

Purpose: To elucidate the structural-functional connectivity (SC-FC) coupling in white matter (WM) tracts in patients with major depressive disorder (MDD).

Methods: A total of 178 individuals diagnosed with MDD and 173 healthy controls (HCs) were recruited for this study. The Euclidean distance was calculated to assess SC-FC coupling.

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Article Synopsis
  • Abnormalities in the connectivity between brain structures and their functions have been found in patients with major depressive disorder (MDD), but the differences across brain regions and their biological mechanisms remain unclear.
  • A study involving 182 MDD patients and 157 healthy controls assessed these connectivity differences using machine learning models, showing promising results for using these patterns as diagnostic biomarkers.
  • Findings indicated increased connectivity in certain brain networks among MDD patients, linked to neurotransmitter distributions and gene expression related to neuron function and signaling, suggesting potential avenues for targeted treatments.
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  • Emotion recognition is vital for enhancing human-computer interaction, and the study introduces the Mixed Attention-based Convolution and Transformer Network (MACTN) as a novel model using EEG data to capture emotional states.
  • The model employs depth-wise and separable convolutions for local feature extraction and a self-attention-based transformer for global context, along with channel attention to optimize emotion-channel relationships.
  • MACTN shows significant improvements in emotion recognition accuracy in both online and offline evaluations and won the Emotional BCI Competition at the World Robot Contest, with its source code available for public use.
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Climate change has become an unavoidable problem in achieving sustainable development. As one of the major industries worldwide, tourism can make a significant contribution to mitigating climate change. The main objective of the paper is to assess the development level of low-carbon tourism from multi-aspect, using the Yellow River Basin as an example.

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A significant industrial transformation in China's tourism sector is currently taking place in response to carbon peak and carbon neutrality targets. This paper applies the data envelopment analysis (DEA) model to calculate the efficiency of the tourism industry under carbon emission constraints and further investigates its influencing factors through the Tobit regression. The results are as follows: (1) The tourism efficiency under carbon emission constraints of China from 2000 to 2019 showed a trend of first rising and then declining, and there were obvious regional differences; (2) from 2000 to 2019, the total factor productivity of tourism in China increased significantly, while the contributions of technical progress, pure technical efficiency, and scale efficiency decreased sequentially; (3) the factors of industrial structure, transportation convenience, economic development level, degree of opening to the outside world, and the level of scientific and technological development have varying degrees of influence on tourism efficiency.

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  • Functional near-infrared spectroscopy (fNIRS) is a noninvasive brain imaging method gaining popularity in emotion recognition research due to its high spatial resolution and real-time capabilities.
  • This study developed an fNIRS emotion recognition database using videos, and introduced a new deep learning model called the dual-branch joint network (DBJNet) to improve emotion recognition across different participants.
  • The proposed model successfully distinguished between various emotions, achieving high accuracy rates, and demonstrated that combining different branches of the neural network enhances decoding performance, paving the way for fNIRS applications in brain-computer interfaces.
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The brain-computer interface (BCI), also known as a brain-machine interface (BMI), has attracted extensive attention in biomedical applications. More importantly, BCI technologies have substantially revolutionized early predictions, diagnostic techniques, and rehabilitation strategies addressing acute diseases because of BCI's innovations and clinical translations. Therefore, in this chapter, a comprehensive description of the basic concepts of BCI will be exhibited, and various visualization techniques employed in BCI's medical applications will be discussed.

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Patient-dependent seizure detection based on intracranial electroencephalography (iEEG) has made significant progress. However, due to the difference in the locations and number of iEEG electrodes used for each patient, patient-independent seizure detection based on iEEG has not been carried out. Additionally, current seizure detection algorithms based on deep learning have outperformed traditional machine learning algorithms in many performance metrics.

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Automatic seizure detection algorithms are necessary for patients with refractory epilepsy. Many excellent algorithms have achieved good results in seizure detection. Still, most of them are based on discontinuous intracranial electroencephalogram (iEEG) and ignore the impact of different channels on detection.

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Background: Detection of mild cognitive impairment (MCI) is essential to screen high risk of Alzheimer's disease (AD). However, subtle changes during MCI make it challenging to classify in machine learning. The previous pathological analysis pointed out that the hippocampus is the critical hub for the white matter (WM) network of MCI.

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Early diagnosis of mild cognitive impairment (MCI) fascinates screening high-risk Alzheimer's disease (AD). White matter is found to degenerate earlier than gray matter and functional connectivity during MCI. Although studies reveal white matter degenerates in the limbic system for MCI, how other white matter degenerates during MCI remains unclear.

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The electroencephalography (EEG) microstate has recently emerged as a new whole-brain mapping tool for studying the temporal dynamics of the human brain. Meanwhile, the neuromodulation effect of external stimulation on the human brain is of increasing interest to neuroscientists. Acupuncture, which originated in ancient China, is recognized as an external neuromodulation method with therapeutic effects.

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. Decoding imagined speech from brain signals could provide a more natural, user-friendly way for developing the next generation of the brain-computer interface (BCI). With the advantages of non-invasive, portable, relatively high spatial resolution and insensitivity to motion artifacts, the functional near-infrared spectroscopy (fNIRS) shows great potential for developing the non-invasive speech BCI.

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. By detecting abnormal white matter changes, diffusion magnetic resonance imaging (MRI) contributes to the detection of juvenile myoclonic epilepsy (JME). In addition, deep learning has greatly improved the detection performance of various brain disorders.

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As a world intangible cultural heritage, acupuncture is considered an essential modality of complementary and alternative therapy to Western medicine. Despite acupuncture's long history and public acceptance, how the cortical network is modulated by acupuncture remains largely unclear. Moreover, as the basic acupuncture unit for regulating the central nervous system, how the cortical network is modulated during acupuncture at the Hegu acupoint is mostly unclear.

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The human auditory cortex is recently found to contribute to the frequency following response (FFR) and the cortical component has been shown to be more relevant to speech perception. However, it is not clear how cortical FFR may contribute to the processing of speech fundamental frequency (F0) and the dynamic pitch. Using intracranial EEG recordings, we observed a significant FFR at the fundamental frequency (F0) for both speech and speech-like harmonic complex stimuli in the human auditory cortex, even in the missing fundamental condition.

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Epilepsy is one of the largest neurological diseases in the world, and juvenile myoclonic epilepsy (JME) usually occurs in adolescents, giving patients tremendous burdens during growth, which really needs the early diagnosis. Advanced diffusion magnetic resonance imaging (MRI) could detect the subtle changes of the white matter, which could be a non-invasive early diagnosis biomarker for JME. Transfer learning can solve the problem of insufficient clinical samples, which could avoid overfitting and achieve a better detection effect.

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In tonal languages such as Chinese, lexical tone with varying pitch contours serves as a key feature to provide contrast in word meaning. Similar to phoneme processing, behavioral studies have suggested that Chinese tone is categorically perceived. However, its underlying neural mechanism remains poorly understood.

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In tonal languages, like Chinese, lexical tone serves as a key feature to provide contrast in word meaning. Behavior studies suggest that Mandarin Chinese tone is categorically perceived. However, the neural mechanism underlying Mandarin tone perception is still poorly understood.

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