Publications by authors named "Xiaopen Ma"
Article Synopsis
- * The enzyme geranylgeranyl diphosphate synthase (GGPPS) is specifically found in renal tubular cells of mouse kidneys, with its expression increasing with age, and it was observed that low GGPPS levels are present in human ADPKD tissues.
- * Deleting GGPPS in mouse models led to the development of cystic kidneys and early death due to renal complications, highlighting GGPPS's importance in PKD and suggesting potential new treatments based on these findings.
