Background And Purpose: Creutzfeldt-Jakob disease (CJD) is a transmissible spongiform encephalopathy characterized by rapid onset and high mortality. Despite considerable progress in the treatment and diagnosis of CJD, patient prognosis remains poor. Many studies have found that the immune response is associated with the pathophysiology of CJD.
View Article and Find Full Text PDFObjective: To investigate the effect of PM2. 5on the respiratory tract flora in the SHR / NCrl rats.
Methods: Through the simulation of real air pollution and mixed gas exposure, the establishment of acute exposure to air pollution in low, medium and high concentration of animal models, to detect the distribution of bacterial flora before and after the dust exposure in the throat and respiratory mucosa of SHR rats.