Cancer cells circumvent immune surveillance via diverse strategies. In accordance, a large number of complex studies of the immune system focusing on tumor cell recognition have revealed new insights and strategies developed, largely through major histocompatibility complexes (MHCs). As one of them, tumor-specific MHC-II expression (tsMHC-II) can facilitate immune surveillance to detect tumor antigens, and thereby has been used in immunotherapy, including superior cancer prognosis, clinical sensitivity to immune checkpoint inhibition (ICI) therapy and tumor-bearing rejection in mice.
View Article and Find Full Text PDFNational environmental protection supervision and control has become essential means to regulate the environmental behavior of enterprises. Furthermore, the optimization, promotion, and sustainability of relevant policies are key topics of inquiry. Taking the implementation of national environmental protection supervision policies as the time series, this paper studies the impact of national environmental protection supervision and control on corporate production efficiency.
View Article and Find Full Text PDFThe public demand for urban green growth (UGG) varies greatly due to climate conditions, resource endowments, geographical location; thus, understanding the coupling relationship between public demand and government supply is important to optimize government investment. This paper aims to evaluate the coupling coordination of UGG between public demand and government supply. An index system consisting of six aspects, including environment, society, economy, population, production and life, was used to evaluate the government supply.
View Article and Find Full Text PDFSci Total Environ
July 2019
The emerging threat to the coastal urban ecosystems from increased intensity and frequency of weather events is a compelling reason for improving our understanding of the integrity of the existing ecosystem. Resilience of an ecosystem is a critical property that aids recovery and adaptation when subject to intense stress. Quantifying the resilience of an ecological system requires a detailed understanding of the vulnerabilities and interactions within a complex web of interconnected social, technological and economic networks.
View Article and Find Full Text PDFAr/O plasma irradiation is proposed for post-treatment of vanadium dioxide (VO₂) films. Oxidation and surface migration were observed in the VO₂ films following irradiation. This combined effect leads to an effective stoichiometry refinement and microstructure reconstruction in the interfacial area.
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