Publications by authors named "Xiaoma Cao"
Enamel adhesion is acknowledged as durable; however, achieving long-lasting dentin adhesion remains a formidable challenge due to degradation of exposed collagen matrix after acid-etching of dentin. The idea of developing an enamel-like adhesion interface holds great promise in achieving enduring dentin adhesion. In this study, we constructed an enamel-like adhesion interface using a rapid remineralization strategy comprising an acidic primer and a rapid remineralization medium.
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- The study addresses challenges in guided bone regeneration (GBR) membranes, focusing on integrating mechanical properties with degradation rates to treat critical bone defects.
- Researchers developed a new GBR membrane inspired by fish scales, using epigallocatechin gallate and biomimetic mineralization, resulting in a structure similar to natural bone.
- The newly created membrane demonstrated excellent mechanical and biological properties, promoting bone repair and regeneration in both laboratory cell cultures and animal models, showcasing its potential for clinical applications.
[Lipopolysaccharide of Porphyromonas gingivalis promotes the autophagy of human gingival fibroblasts].
Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi
March 2017
Objective To investigate the impact of lipopolysaccharide of Porphyromonas gingivalis (Pg-LPS) on the autophagy of human gingival fibroblasts (HGFs). Methods Firstly, HGFs was stimulated with 10 μg/mL Pg-LPS for 12 hours or 24 hours. Rapamycin was used as a positive control.
View Article and Find Full Text PDF[Establishment and identification of transiently expression system of bone marrow stromal cells modified by osteoprotegerin gene].
Hua Xi Kou Qiang Yi Xue Za Zhi
December 2008
Objective: In oder to treat periodontitis by using tissue engineering and gene engineering technology, the article established an transient expression system of bone marrow stromal cells (BMSC) modified by osteoprotegerin (OPG) gene and detected its expression using eukaryotic secreted expression pSecTag2/B-OPG plasmid.
Methods: By solation and culture of BMSC in vitro, the identified recombined plasmid was transiently transfected into BMSC by Lipofectamine 2000 and OPG expression in BMSC was determined by RT-PCR and Western blot in 6 weeks.
Results: The fragments of the recombinant plasmid digested with Hind III, EcoR I and BamH I and examined by 10 g/L agarose electrophoresis, were consistent with predicted size.