A novel one-stepped synthesized Schiff-base fluorescence probe for specific recognition of zinc ions with highly sensitive and its application in living cells.

Fluorescent turn-on receptors are extensively employed for the detection of Zn ions contamination in the environment due to its simplicity, convenience and portability. However, developing highly sensitive and cell-imageable fluorescent turn-on probe for the recognition of Zn ions in living organisms remains a significant challenge. Herein, we have successfully synthesized a novel Schiff base probe (HL) with a significant fluorescence turn-on response (Zn ions) by one-step synthetic method.

Do social economic status modify the association between air pollution and depressive or anxiety symptoms? A big sample cross-sectional study from the rural areas of Central China.

Background: Fewer studies have examined the relationship between air pollution and depressive or anxiety symptoms in rural residents. Social economic status (SES), as an important indicator of the current state of socioeconomic development, we know little about how it modifies the relationship between air pollution and symptoms of depression or anxiety.

Methods: The patient health questionnaire (PHQ-2) and generalized anxiety scale (GAD-2) were used to learn about the prevalence of depressive and anxiety symptoms, the social economic status of the participants was categorized into two levels: lower and higher, and a binary logistic regression model was used to analyze the relationship between air pollution and residents' symptoms of depression or anxiety.

The protease Lon prolongs insect lifespan by responding to reactive oxygen species and degrading mitochondrial transcription factor A.

Diapause is a widespread adaptation of insects that enables them to survive during unfavorable seasons and is characterized by suppressed metabolism and increased lifespan. Previous works have demonstrated that high levels of reactive oxygen species (ROS) and hypoxia-inducible factor-1α (HIF-1α) in the pupal brain of the moth Helicoverpa armigera induce diapause and extend lifespan by downregulating mitochondrial transcription factor A (TFAM). However, the molecular mechanisms of ROS-HIF-1α regulating metabolic activity to extend lifespan are still poorly understood.

Improved Antibacterial Properties of Polylactic Acid-Based Nanofibers Loaded with ZnO-Ag Nanoparticles through Pore Engineering.

In the post-epidemic era, bio-based protective fiber materials with active protective functions are of utmost importance, not only to combat the spread of pathogens but also to reduce the environmental impact of petroleum-based protective materials. Here, efficient antibacterial polylactic acid-based (PLA-based) fibers are prepared by solution blow spinning and their pore structures are regulated by controlling the ratio of the solvent components in the spinning solutions. The porous PLA-based fibers exhibit antibacterial efficiencies of over 99% against and over 98% against , which are significantly higher than that of the nonporous PLA-based fibers.

Epigenomics Analysis of the Suppression Role of via H3K9 Deacetylation in Preadipocyte Differentiation.

Sirtuin 1 () overexpression significantly inhibits lipid deposition during yak intramuscular preadipocyte (YIMA) differentiation; however, the regulatory mechanism remains unknown. We elucidated the role of in YIMA differentiation using lentivirus-mediated downregulation technology and conducted mRNA-seq and ChIP-seq assays using H3K9ac antibodies after overexpression in order to reveal targets during YIMA adipogenesis. Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analyses were performed in order to identify the functional annotation of common genes.

Research progress in preparation, properties, and applications of medical protective fiber materials.

A variety of public health events seriously threaten human life and health, especially the outbreak of COVID-19 at the end of 2019 has caused a serious impact on human production and life. Wearing personal protective equipment (PPE) is one of the most effective ways to prevent infection and stop the spread of the virus. Medical protective fiber materials have become the first choice for PPE because of their excellent barrier properties and breathability.

Mechanical Force-Induced Blue-Shifted and Enhanced Emission for AIEgens.

Mechanochromic (MC) luminescence of organic molecules has been emerging as a promising smart material for optical recording and memory devices. At the same time, pressure-induced blue-shifted and enhanced luminescence are rarely reported now. Herein, a series of cyanostilbene-based AIEgens with different substituents were synthesized to evaluate the influence of morphology transformation and push-pull electronic effect on the MC luminescence.

ROS elevate HIF-1α phosphorylation for insect lifespan through the CK2-MKP3-p38 pathway.

Diapause in insects is akin to dauer in Caenorhabditis elegans and hibernation in vertebrates, characterized by metabolic depression and lifespan extension. Previous studies have shown that reactive oxygen species (ROS) and hypoxia-inducible factor-1α (HIF-1α) in brains of diapause-destined pupae are more abundant than those in nondiapause-destined pupae in Helicoverpa armigera, but the ROS regulating HIF-1α activity remain unknown. Here, we showed that high ROS levels in brains of diapause-destined pupae resulted in low casein kinase 2 (CK2) activity and that downregulation of CK2 caused low expression of mitogen-activated protein kinase phosphatase 3 (MKP3), which is an inhibitor of p-p38.

Visual Detection of COVID-19 from Materials Aspect.

Abstract: In the recent COVID-19 pandemic, World Health Organization emphasized that early detection is an effective strategy to reduce the spread of SARS-CoV-2 viruses. Several diagnostic methods, such as reverse transcription-polymerase chain reaction (RT-PCR) and lateral flow immunoassay (LFIA), have been applied based on the mechanism of specific recognition and binding of the probes to viruses or viral antigens. Although the remarkable progress, these methods still suffer from inadequate cellular materials or errors in the detection and sampling procedure of nasopharyngeal/oropharyngeal swab collection.

Remote preparation and manipulation of squeezed light.

Remote state preparation enables one to create and manipulate a quantum state based on the shared entanglement between distant nodes. Here, we experimentally demonstrate remote preparation and manipulation of squeezed light. By performing a homodyne projective measurement on one mode of the continuous variable entangled state at Alice's station, a squeezed state is created at Bob's station.

Experimental Demonstration of Remotely Creating Wigner Negativity via Quantum Steering.

Non-Gaussian states with Wigner negativity are of particular interest in quantum technology due to their potential applications in quantum computing and quantum metrology. However, how to create such states at a remote location remains a challenge, which is important for efficiently distributing quantum resource between distant nodes in a network. Here, we experimentally prepare an optical non-Gaussian state with negative Wigner function at a remote node via local non-Gaussian operation and shared Gaussian entangled state existing quantum steering.

Visualization of Enantiorecognition and Resolution by Chiral AIEgens.

Enantioselective recognition and separation have attracted much attention in pharmaceutical analysis, food chemistry, and life science. Herein, we propose an efficient strategy to achieve such purposes using optically active luminogens with aggregation-induced emission (AIE) characteristics. These AIE luminogens (AIEgens) show strong enantiomeric discrimination for 12 kinds of chiral acids and unprotected amino acids.

Experimental demonstration of the conversion of local and correlated Gaussian quantum coherence.

Quantum coherence plays an important role in quantum information processing. In this Letter, we experimentally demonstrate the conversion of local and correlated Gaussian quantum coherence in the process of converting two squeezed states into an entangled state. We also investigate the relationship among total, local, and correlated coherence and show that the total coherence of a two-mode Gaussian state is the sum of local quantum coherence of each mode and the correlated quantum coherence between two modes.

Deterministic Distribution of Multipartite Entanglement and Steering in a Quantum Network by Separable States.

As two valuable quantum resources, Einstein-Podolsky-Rosen entanglement and steering play important roles in quantum-enhanced communication protocols. Distributing such quantum resources among multiple remote users in a network is a crucial precondition underlying various quantum tasks. We experimentally demonstrate the deterministic distribution of two- and three-mode Gaussian entanglement and steering by transmitting separable states in a network consisting of a quantum server and multiple users.

Formation of Stereocomplex Crystal and Its Effect on the Morphology and Property of PDLA/PLLA Blends.

Stereocomplex-polylactic acid (SC-PLA) is obtained in poly(D-lactic) acid/poly(L-lactic) acid (PDLA/PLLA) blends under adjusting processing conditions. It is found that the degree of crystallinity of overall SC-PLA is up to 43.7% in PDLA/PLLA blends of 1:1 mass ratio.

Copper-Catalyzed Enantioconvergent Cross-Coupling of Racemic Alkyl Bromides with Azole C(sp )-H Bonds.

The development of enantioconvergent cross-coupling of racemic alkyl halides directly with heteroarene C(sp )-H bonds has been impeded by the use of a base at elevated temperature that leads to racemization. We herein report a copper(I)/cinchona-alkaloid-derived N,N,P-ligand catalytic system that enables oxidative addition with racemic alkyl bromides under mild conditions. Thus, coupling with azole C(sp )-H bonds has been achieved in high enantioselectivity, affording a number of potentially useful α-chiral alkylated azoles, such as 1,3,4-oxadiazoles, oxazoles, and benzo[d]oxazoles as well as 1,3,4-triazoles, for drug discovery.

Analysis of microstructure characteristics and mechanical properties of beetle forewings, Allomyrina dichotoma.

In this study, the internal microstructure of the forewings of Allomyrina dichotoma is investigated by scanning electron microscopy (SEM) analysis. The results of SEM test show that the inner microstructure of the forewings possesses an integrated sandwich-like plate supported by trabeculae, which is composed of upper and lower skins of unequal thicknesses, and a honeycomb core with trabeculae. Beetle forewing is a natural composite material composed of chitin fibres and proteins.

Quantum beam splitter for orbital angular momentum of light: quantum correlation by four-wave mixing operated in a nonamplifying regime.

Nondegenerate four-wave mixing (FWM) process based on a double-Λ scheme in hot alkali metal vapor is a versatile tool in quantum state engineering, quantum imaging, and quantum precision measurements. In this Letter, we investigate the generation of quantum correlated twin beams which carry nonzero orbital angular momentums (OAMs) based on the FWM process in hot cesium vapor. The amplified probe beam and the newly generated conjugate beam in the FWM process have the same and opposite topological charge as the seed beam, respectively.

Connecting two Gaussian cluster states by quantum entanglement swapping.

Cluster state is an important resource for one-way quantum computation and quantum network. In this paper, we present a scheme for connecting two Gaussian cluster states by entanglement swapping, which can be used to connect two local quantum networks composed by cluster states. The connection schemes between different types of four-mode cluster states are analyzed and we show that the structure of the output states after entanglement swapping may be not the same as that of the input states.

Deterministic quantum teleportation through fiber channels.

Quantum teleportation, which is the transfer of an unknown quantum state from one station to another over a certain distance with the help of nonlocal entanglement shared by a sender and a receiver, has been widely used as a fundamental element in quantum communication and quantum computation. Optical fibers are crucial information channels, but teleportation of continuous variable optical modes through fibers has not been realized so far. Here, we experimentally demonstrate deterministic quantum teleportation of an optical coherent state through fiber channels.

A Unique Strategy for Polyethylene Glycol/Hybrid Carbon Foam Phase Change Materials: Morphologies, Thermal Properties, and Energy Storage Behavior.

Polyethylene glycol (PEG)/hybrid carbon foam (CF) phase change materials (PCMs) were prepared by integrating PEG into CF via dynamic-vacuum impregnation. The hybrid CF was first synthesized by mixtures of graphene oxide (GO) and carbon nanotubes (CNTs) with different volume ratios. The morphologies, chemical structures, thermal conductivities, shape-stabilization levels, and photo-thermal energy conversion levels of these composite PCMs were characterized systematically.

Adaptation of brain functional stream architecture in athletes with fast demands of sensorimotor integration.

Training-induced neuroplasticity has been described in athletes' population. However, it remains largely unknown how regular training and sports proficiency modifies neuronal circuits in the human brain. In this study, we used voxel-based morphometry and stepwise functional connectivity (SFC) analyses to uncover connectivity changes in the functional stream architecture in student-athletes at early stages of sensorimotor skill training.

Mixed Incoherent Far-Field and Near-Field Source Localization under Uniform Circular Array.

A high-accuracy algorithm is presented for the localization of mixed incoherent near-field and far-field narrow-band sources under uniform circular array (UCA). Herein, considering that it is difficult to classify the mixed sources, we first decouple mixed sources’ angles and ranges by calculating centro-symmetric sensors’ phase differences. Then, as the phase differences including only sources’ angles can be transformed as indefinite equations, each source’s azimuth angle and elevation angle are obtained by performing the least squares method.

Compact sub-kilohertz low-frequency quantum light source based on four-wave mixing in cesium vapor.

Using a nondegenerate four-wave mixing (FWM) process based on a double-Λ scheme in hot cesium vapor, we demonstrate a compact diode-laser-pumped quantum light source for the generation of quantum correlated twin beams with a maximum squeezing of 6.5 dB. The squeezing is observed at a Fourier frequency in the audio band down to 0.