Congenital Sternoclavicular Sinus-Case Series of a Rare Lower Neck Deformity.

Objectives: We encountered patients with a congenital cutaneous sinus tract in the sternoclavicular joint region, which we designate as "congenital sternoclavicular sinus (CSCS)." The aim of this investigation is to enhance recognition of this subtle yet noteworthy entity and develop standardized protocols for its management.

Patients And Methods: Between 2013 and 2023, 172 patients, including 78 males and 94 females, were referred to our institution for the management of CSCS.

Construction of FeNi@graphite nanoparticles via corrosion-like transformation from NiFeO and surface graphitization in flexible carbon nanofibers to achieve strong wideband microwave absorption.

Recently, microwave absorption (MA) materials have attracted intensive research attention for their ability to counteract the effects of ever-growing electromagnetic pollution. However, conventional microwave absorbers suffer from complex fabrication processes, poor stability and different optimal thicknesses for minimum reflection loss (RL) and widest effective absorption bandwidth (EAB). To address these issues, we have used electrospinning followed by high-temperature annealing in argon to develop a flexible microwave absorber with strong wideband absorption.

Construction of a heterojunction with fast charge transport channels for photocatalytic hydrogen evolution a synergistic strategy of Co-doping and crystal plane modulation.

Carrier spatial separation efficiency and active electron density are the key factors affecting photocatalytic hydrogen evolution activity. Heterojunction catalysts with fast charge separation and directed electron transport systems were successfully prepared by a synergistic modification strategy of transition metal (Co) doping and crystal plane modulation. The optimized electronic structure and enhanced reaction kinetics enabled unidirectional electron transfer.

[The managements of cervical chondrocutaneous branchial remnants].

To investigate the embryologic origin and diagnosis and management of cutaneous cartilage remains of gill origin in the neck. A total of 15 patients with cervical chondrocutaneous branchial remnants treated in Guangdong Provincial People's Hospital from January 2005 to December 2021 were retrospectively analyzed. They had a common feature showing a tumor in the lower third of the front of sternocleidomastoid muscle.

[Clinical application of modified fistulectomy in the treatment of congenital pyriform sinus fistula based on segmental anatomy of fistula].

To discuss the clinical application and significance of the modified piriform fossa fistulectomy based on segmental anatomy of fistula. The clinical data of 84 patients with CPSF treated by modified pyriform sinus fistulectomy were analyzed retrospectively. The modified piriform fossa fistula resection adopts the fistula anterograde anatomy method to fine dissect the fistula.

Self-Assembly of CsPbBr Nanocubes into 2D Nanosheets.

All-inorganic metal halide perovskites have attracted considerable attention due to their high application potentials in optoelectronics, photonics, and energy conversion. Herein, two-dimensional (2D) CsPbBr nanosheets with a thickness of about 3 nm have been synthesized through a simple chemical process based on a hot-injection technique. The lateral dimension of CsPbBr nanosheets ranges from 11 to 110 nm, which can be tuned by adjusting the ratio of short ligands (octanoic acid and octylamine) over long ligands (oleic acid and oleylamine).

HTR7 promotes laryngeal cancer growth through PI3K/AKT pathway activation.

Background: Laryngeal cancer is a common malignancy of the head and neck, it's important to find novel targets for its therapy. The 5-hydroxytryptamine receptor 7 (HTR7) belongs to the G protein-coupled receptors (GPCRs) family which are easily druggable in diseases; however, its role in laryngeal cancer remains unknown.

Methods: Colony formation assay, Soft agar growth assay, BrdU incorporation assay and MTT assay were used to analyze the effect of HTR7 on laryngeal cancer cell proliferation.

Upregulation of Long Noncoding RNA_GAS5 Suppresses Cell Proliferation and Metastasis in Laryngeal Cancer via Regulating PI3K/AKT/mTOR Signaling Pathway.

Background: Laryngeal cancer is one of the most common malignant tumors among head and neck cancers. Accumulating studies have indicated that long noncoding RNAs (lncRNAs) play an important role in laryngeal cancer occurrence and progression, however, the functional roles and relative regulatory mechanisms of lncRNA growth arrest-specific transcript 5 (GAS5) in laryngeal cancer progression remain unclear.

Methods: The expression of lncRNA GAS5 in both laryngeal cancer tissues and cell lines was evaluated using quantitative reverse transcription-polymerase chain reaction (RT-qPCR) assay.

MiR-125a-5p inhibits cell proliferation, cell cycle progression, and migration while promoting apoptosis in head and neck cancers by targeting ERBB3.

Objective: Head and neck cancer is one of the most common cancer types worldwide. MicroRNAs play a vital regulatory role in the occurrence and development of cancer. The objective of this study is to explore the mechanism of miR-125a-5p in the proliferation, migration and apoptosis of head and neck cancer cells and define its target genes.

[Bilateral pyriform sinus fistulas: a case report].

A 6 year-old boy, who complained right neck abscesses and X-ray showed left pyriform fistula, was diagnosed as bilateral pyriform sinus fistulas. For bilateral pyriform sinus fistulas, endoscopic CO2laser cauterization should be the first treatment choice.

Adaptation of SARS-CoV-2 in BALB/c mice for testing vaccine efficacy.

The ongoing coronavirus disease 2019 (COVID-19) pandemic has prioritized the development of small-animal models for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We adapted a clinical isolate of SARS-CoV-2 by serial passaging in the respiratory tract of aged BALB/c mice. The resulting mouse-adapted strain at passage 6 (called MASCp6) showed increased infectivity in mouse lung and led to interstitial pneumonia and inflammatory responses in both young and aged mice after intranasal inoculation.

Lack of Vertical Transmission of Severe Acute Respiratory Syndrome Coronavirus 2, China.

A woman with coronavirus disease in her 35th week of pregnancy delivered an infant by cesarean section in a negative-pressure operating room. The infant was negative for severe acute respiratory coronavirus 2. This case suggests that mother-to-child transmission is unlikely for this virus.

Long noncoding RNA FOXD2-AS1 enhances chemotherapeutic resistance of laryngeal squamous cell carcinoma via STAT3 activation.

Laryngeal squamous cell carcinoma (LSCC) is a common head and neck cancer. Despite recently improved management of LSCC, chemotherapy resistance of patients remains a challenge. In this study, we identified that long noncoding RNA FOXD2-AS1 regulates LSCC therapeutic resistance by augmenting LSCC stemness.

The prognostic value of tumor budding in laryngeal squamous cell carcinoma.

Background: The predictive value of tumor budding in several cancers is of the essence. The 5-year survival of laryngeal squamous cell carcinoma patients is decreasing despite the improvement of therapy. In order to help improve the prognosis of LSCC patients, we aimed to investigate the value of tumor budding on the prognosis in laryngeal squamous cell cancer (LSCC) by the pathological characteristics of the surgical cases.

Co-CoO/ZnFeO encapsulated in carbon nanowires derived from MOFs as electrocatalysts for hydrogen evolution.

Transition metals are increasingly attracting interest in electrocatalysts for use in water decomposition due to their excellent catalytic activity and stability. Simultaneously, metal-organic frameworks with designable metal ion centers and organic ligands are the promising precursors for the one-step synthesis of metal encapsulated in carbon composites for alkaline hydrogen evolution reaction (HER). Herein, we report the successful construction of Co-CoO/ZnFeO encapsulated in carbon nanowires (Co-CoO/ZnFeO@CNWs) by annealing as-synthesized nanowire Co/Zn/Fe-MOF at 400 °C in N.

The Role of Insulin Glargine and Human Insulin in the Regulation of Thyroid Proliferation Through Mitogenic Signaling.

Our aim was to investigate whether human insulin (HI) or insulin glargine treatment could promote the proliferation of thyroid cells and determine the association between type 2 diabetes and thyroid disease. Rats were treated with different doses of HI and insulin glargine. Plasma glucose and the phosphorylation levels of the insulin receptor (IR), insulin-like growth factor 1 receptor (IGF-1R), protein kinase B (Akt), and extracellular signal-regulated kinase 1/2 (ERK1/2) were measured.

PLOD2 contributes to drug resistance in laryngeal cancer by promoting cancer stem cell-like characteristics.

Background: Advanced stage laryngeal squamous cell carcinoma (LSCC) presents a poor prognosis; thus, there is a great need to identify novel prognostic molecular markers. Procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 (PLOD2) is thought to be a novel prognostic factor in several cancers, but its role in LSCC remains unknown. Cancer stem cells (CSCs) are responsible for most instances of tumor recurrence and the development of drug resistance and have been proven to be present in head and neck cancers.

A Retrospective Study of The Prognostic Significance of Preoperative Plasma Fibrinogen, Mean Platelet Volume, and the Neutrophil-to-Lymphocyte Ratio in Patients with Laryngeal Squamous Cell Carcinoma.

BACKGROUND This study aimed to evaluate the prognostic significance of plasma fibrinogen, serum albumin, the mean platelet volume (MPV), and the neutrophil-to-lymphocyte ratio (NLR) in patients with laryngeal squamous cell carcinoma (LSCC) who underwent surgical resection. MATERIAL AND METHODS A retrospective study included 110 patients with LSCC who underwent surgical resection between January 2008 to June 2015. Clinicopathologic and demographic data were recorded.

Effect of insulin on thyroid cell proliferation, tumor cell migration, and potentially related mechanisms.

Background: Diabetes has recently been identified as a risk factor for a variety of cancers, possibly due to hyperinsulinemia or exogenous insulin use. Thyroid cancer is the most common endocrine malignancy, and its incidence has been exponentially increasing worldwide at an alarming rate. The aim of this study was to establish whether insulin use affects thyroid cancer development and progression, specifically cell proliferation and migration in vitro.

Hierarchical Honeycomb Br-, N-Codoped TiO with Enhanced Visible-Light Photocatalytic H Production.

The halogen elements modification strategy of TiO encounters a bottleneck in visible-light H production. Herein, we have for the first time reported a hierarchical honeycomb Br-, N-codoped anatase TiO catalyst (HM-Br,N/TiO) with enhanced visible-light photocatalytic H production. During the synthesizing process, large amounts of meso-macroporous channels and TiO nanosheets were fabricated in massive TiO automatically, constructing the hierarchical honeycomb structure with large specific surface area (464 m g).

Clinical predictor of postoperative hyperkalemia after parathyroidectomy in patients with hemodialysis.

Objective: Hyperkalaemia is one of the most common reasons for patients requiring emergency treatment. This study is to investigate the risk factors of postoperative hyperkalemia in renal failure patients undergoing parathyroidectomy with autotransplantation (PTXa).

Methods: One hundred and eight patients [ 54 men and 54 women; age, 45.

Survival in Vivo Canine Phonation Model Without Stimulation.

Objectives: We describe a survival nonstimulated in vivo canine phonation model using distending laryngoscope, cramp frame, and constant humidified glottal airflow to elicit phonation.

Methods: Five beagle dogs were involved in this study. One cuffed endotracheal tube was placed below the glottis through the tracheotomy and delivered humidified airflow to the glottis.

Marital status and survival of patients with kidney cancer.

Background: The relationship between marital status and prognosis of kidney cancer has not been explored in detail. In this study, we aimed to investigate the impact of marital status on survival outcomes in kidney cancer.

Methods: We used the Surveillance, Epidemiology and End Results (SEER) program to identify 112860 patients with kidney cancer diagnosed in 2004 through 2013.

Serum parathyroid hormone and alkaline phosphatase as predictors of calcium requirements after total parathyroidectomy for hypocalcemia in secondary hyperparathyroidism.

Background: To prevent hypocalcemia, this study examined the efficiency of a calcium supplement formula guided by predicted calcium requirement in patients with renal failure after parathyroidectomy with autotransplantation.

Methods: In the first phase, a protocol was followed whereby intravenous calcium gluconate was repeatedly titrated based on serum calcium levels in 22 patients with parathyroidectomy with autotransplantation. In the second phase, the first equation protocol was applied in 74 patients with parathyroidectomy with autotransplantation and revised.

Synthesis of ordered mesoporous LaO-ZrO composites with encapsulated Pt NPs and the effect of La-dopping on catalytic activity.

In this work, we report a feasible approach to synthesize a ternary nanocomposites, Pt/lanthanum doped mesoporous zirconium oxide (Pt/LaO-ZrO), via an effective two-step method. Ordered mesoporous LaO-ZrO composites were firstly fabricated with mesoporous silica KIT-6 as a hard template. Subsequently, uniform Pt nanoparticles encapsulated by 4 hydroxyl-terminated poly (amidoamine) (G4-OH PAMAM) dendrimers were deposited on the LaO-ZrO composites.