[Intercropping history, pattern, and case analysis of Chinese medicinal material].

Intercropping is a traditional and widely used planting pattern, and different intercropped plants have differences in spatial distribution and morphological structure compared with monoculture. Therefore, intercropping can realize efficient acquisition of limited space resources and efficient conversion of existing resources by utilizing the principle of niche complementarity of composite groups, weakening interspecific or intra-specific competition, and enhancing their complementary growth. Intercropping of Chinese medicinal material(CMM) has experienced the evolution of more than two thousand years from its founding to inheritance and development.

[Application status of methotrexate in patients with rheumatoid arthritis].

Objective: To investigate the current status of methotrexate (MTX) application in rheumatoid arthritis (RA) patients.

Methods: The clinical and laboratory data of RA patients who attended in the Department of Rheumatology and Immunology of Peking University Third Hospital from January 1, 2022 to November 31, 2023 were collected retrospectively. In order to figure out the relationship between MTX use and RA disease control, we recorded information including the starting dose, maximum dose, current dose, reasons of discontinuation of MTX, .

Relationship Between Fear of Childbirth and Oral Health-Related Quality of Life in Pregnant Women: The Mediating Effect of Pregnancy Anxiety.

Background: Psychosocial health affects oral health-related quality of life. Pregnancy, as a special time for women, produces significant psychological changes. However, the relationship between mental health during pregnancy and oral health-related quality of life is unclear.

Effects of Web-Based Acceptance and Commitment Therapy on Health-Related Outcomes Among Patients With Lung Cancer: A Feasibility Randomized Controlled Trial.

Objective: To identify the feasibility, acceptability, and effectiveness of web-based acceptance and commitment therapy (ACT) on health-related outcomes in patients with lung cancer.

Methods: A feasibility, prospective, parallel, individual-based, assessor-blinded randomized controlled trial was designed. This study was conducted at a third-level hospital in Sichuan Province, China.

Risk Prediction Models as an Emerging Trend for Managing Cancer-Related Fatigue: A Systematic Review.

Aim: To systematically identify, describe and evaluate the existing risk prediction models for cancer-related fatigue.

Design: Systematic review.

Data Sources: Seven databases (EMBASE, Cochrane Database, MEDLINE, CINAHL, CNKI, SinoMed and Wanfang) were conducted from inception to August 14, 2023 and updated in September 15, 2024.

Period circadian clock 3 is crucial for regulation of IL-22-producing type 3 innate lymphoid cells by flavonoids from Shen Ling Bai Zhu San to alleviate colitis.

Type 3 Innate lymphoid cells (ILC3s) functions bear complex response during Inflammatory bowel diseases (IBD). Here, our study first analyzed the main pharmacological components in Shen Ling Bai Zhu San n-butanol extracts (S-Nb), and then explored whether S-Nb administrated immune response of ILC3s, and how it regulates ILC3s. Shen Ling Bai Zhu San (SLBZS) or S-Nb were administrated for 7 days to analyze the frequency of ILC3s and their produced cytokine.

Association of iron homeostasis-related gene polymorphisms with pregnancy and neonatal outcomes in patients with gestational diabetes mellitus.

Objective: The purpose of this study was to assess associations between iron homeostasis-related gene polymorphisms and gestational diabetes mellitus (GDM), adverse pregnancy outcomes, and neonatal outcomes.

Methods: In total, 138 patients with GDM and 74 normal pregnancy controls were recruited. Time-of-flight mass spectrometry was used to genotype single-nucleotide polymorphisms (H63D rs1799945, TMPRSS6 rs855791, GDF15 rs1059369, rs4808793, BMP2 rs173107, C282Y rs3811647, rs1800562, rs269853, TF rs8177240, TFR2 rs7385804, FADS2 rs174577, and CUBN rs10904850) in 12 candidate genes related to iron homeostasis.

The predictive values of C-reactive protein-neutrophil to lymphocyte ratio for the risk of refractory pneumonia in children: a retrospective cohort study.

This cohort study evaluated the associations of C-reactive protein-neutrophil to lymphocyte ratio (C-NLR) and lymphocyte-CRP ratio (LCR) with refractory Mycoplasma pneumoniae pneumonia (RMPP), and the predictive values of C-NLR and LCR for RMPP and prolonged fever in children based on 389 children with MPP. The associations of NLR, C-NLR, and LCR with RMPP and prolonged fever were evaluated by logistic regression analysis. C-NLR was correlated with an increased risk of RMPP in children [odds ratio (OR) = 3.

Amorphous Fe-O-P electro(pre)catalysts for energy-efficient H production coupled with ethylene glycol oxidation.

This study presents the synthesis and electrocatalytic performance of amorphous Fe-O-P nanocages derived from Fe-MOFs for water and ethylene glycol (EG) oxidation. Despite structural and compositional changes, the electrocatalyst in an electrolytic cell with Pt/C shows high activity and reduced cell voltage, efficiently generating H and formic acid in a KOH-EG mixed electrolyte.

Integrated analysis of multi-omics data for the discovery of biomarkers and therapeutic targets for juvenile idiopathic arthritis.

Background: Juvenile idiopathic arthritis (JIA) is a prevalent chronic rheumatic disease affecting children. Current medications merely alleviate symptoms rather than curing the disease. Hence, the identification and development of novel drug targets and biomarkers for JIA are imperative for enhancing treatment efficacy.

Emerging Sialylated Class R Lipooligosaccharides in from Seagulls Has the Potential to Trigger Guillain-Barré Syndrome - Yunnan Province, China, 2018-2023.

What Is Already Known About This Topic?: Lipooligosaccharides from () have a mimicry antigen structure with gangliosides, which explains the mechanism by which caused Guillain-Barré syndrome (GBS).

What Is Added By This Report?: All 12 strains with class R LOSs and specific serotypes were isolated from seagulls in south China. These emerging strains had ganglioside-mimicry antigen structures and possessed a high potential for triggering GBS.

20-Hydroxyeicosatetraenoic Acid Regulates the Src/EGFR/NF-κB Signaling Pathway Via GPR75 to Activate Microglia and Promote TBI in the Immature Brain.

20-Hydroxyeicosatetraenoic acid (20-HETE) is associated with secondary damage in traumatic brain injury (TBI) of the immature brain. Microglial activation is pivotal in this process. However, the underlying mechanism of action remains unknown.

Combination of intravoxel incoherent motion histogram parameters and clinical characteristics for predicting response to neoadjuvant chemoradiation in patients with locally advanced rectal cancer.

Objective: To explore the value of histogram parameters derived from intravoxel incoherent motion (IVIM) for predicting response to neoadjuvant chemoradiation (nCRT) in patients with locally advanced rectal cancer (LARC).

Methods: A total of 112 patients diagnosed with LARC who underwent IVIM-DWI prior to nCRT were enrolled in this study. The true diffusion coefficient (D), pseudo-diffusion coefficient (D), and microvascular volume fraction (f) calculated from IVIM were recorded along with the histogram parameters.