Publications by authors named "Xiaolei Wu"

Soil borne diseases are one of the most serious diseases which often results the decline of vegetables quality and loss of production. Moreover, it is difficult for plants to exhibit disease symptoms in the early stages attributing to strong concealment of soil borne pathogens. Therefore, early detection of pathogens and their physiological races plays an important role in reducing the harm of pathogens associated with diseases of vegetable crops.

View Article and Find Full Text PDF

Introduction: The farnesoid X receptor (FXR) is a crucial regulator in the intestine, maintaining bile acid homeostasis. Inhibiting intestinal FXR shows promise in managing inflammatory bowel and liver diseases by reducing bile acid accumulation. Additionally, changes in FXR expression could serve as a potential biomarker for intestinal diseases.

View Article and Find Full Text PDF

Microbial-induced oil degradation (MIOD) has a wide range of applications, such as microbial enhanced oil recovery and bioremediation of oil pollution. However, our understanding of MIOD is still far from complete. Particularly, how is the dynamics of degradation process at the microscale level with a single-cell resolution remains to be disclosed.

View Article and Find Full Text PDF

Tc is regarded as the most important medical isotope, and its supply issues have garnered significant attention. A simple and efficient separation method was performed for the production of Tc from Mo target in this study. The entire process involves accelerator irradiation, Tc/Mo separation, and target material recovery.

View Article and Find Full Text PDF

Soil salinization is one of the major abiotic stresses affecting plant growth and development. Plant salt tolerance is controlled by complex metabolic pathways. Exploring effective methods and mechanisms to improve crop salt tolerance has been a key aspect of research on the utilization of saline soil.

View Article and Find Full Text PDF
Article Synopsis
  • - Long-term use of fertilizers and intensive farming harms soil health and boosts greenhouse gas emissions, challenging sustainable agriculture; this paper explores organic amendments for winter wheat in China's North Plain to enhance productivity while reducing carbon output.
  • - The study compares two nitrogen levels (N0 and N240) and four organic amendments (straw, manure, mushroom residue, biochar), finding that while N240 significantly boosts wheat yield and soil organic carbon, it also raises carbon emissions; biochar proves most effective at increasing carbon storage.
  • - Overall, N240 with mushroom residue is highlighted as an optimal choice for maximizing wheat yield and soil carbon in the region, and low-cost amendments like mushroom residue can encourage farmers and enhance soil health.
View Article and Find Full Text PDF

Carbon capture, utilization, and storage (CCUS) is an important component in many national net-zero strategies, and ensuring that CO can be safely and economically stored in geological systems is critical. Recent discoveries have shown that microbial processes (e.g.

View Article and Find Full Text PDF

From microbes to humans, organisms perform numerous tasks for their survival, including food acquisition, migration, and reproduction. A complex biological task can be performed by either an autonomous organism or by cooperation among several specialized organisms. However, it remains unclear how autonomy and cooperation evolutionarily switch.

View Article and Find Full Text PDF

Objective: With the modernization of traditional Chinese medicine (TCM) industry, the investment in research and development of new commercial Chinese polyherbal preparations (CCPPs) is increasing, and the varieties of CCPPs are growing. CCPPs play an increasingly important role in the TCM industry. This study has comprehensively summarized and analyzed the current situation of CCPPs that has been on the market in China, and provided suggestions for the research and promotion of CCPPs.

View Article and Find Full Text PDF

Oil reservoirs, being one of the significant subsurface repositories of energy and carbon, host diverse microbial communities affecting energy production and carbon emissions. Viruses play crucial roles in the ecology of microbiomes, however, their distribution and ecological significance in oil reservoirs remain undetermined. Here, we assemble a catalogue encompassing viral and prokaryotic genomes sourced from oil reservoirs.

View Article and Find Full Text PDF

Executive Summary: Microbes are all pervasive in their distribution and influence on the functioning and well-being of humans, life in general and the planet. Microbially-based technologies contribute hugely to the supply of important goods and services we depend upon, such as the provision of food, medicines and clean water. They also offer mechanisms and strategies to mitigate and solve a wide range of problems and crises facing humanity at all levels, including those encapsulated in the sustainable development goals (SDGs) formulated by the United Nations.

View Article and Find Full Text PDF

This study aims to construct the element relationship and extension path of clinical evidence knowledge map with Chinese patent medicine, providing basic technical support for the formation and transformation of the evidence chain of Chinese patent medicine and providing collection, induction, and summary schemes for massive and disorganized clinical data. Based on the elements of evidence-based PICOS, the conventional construction methods of knowledge graph were collected and summarized. Firstly, the data entities related to Chinese patent medicine were classified, and entity linking was performed(disambiguation).

View Article and Find Full Text PDF

The strength-ductility trade-off has long been a Gordian knot in conventional metallic structural materials and it is no exception in multi-principal element alloys. In particular, at ultrahigh yield strengths, plastic instability, that is, necking, happens prematurely, because of which ductility almost entirely disappears. This is due to the growing difficulty in the production and accumulation of dislocations from the very beginning of tensile deformation that renders the conventional dislocation hardening insufficient.

View Article and Find Full Text PDF
Article Synopsis
  • The study aims to understand how microbial dispersal affects the diversity of ecological communities, a key focus in ecology.
  • By using a combined approach of a mathematical model and lab experiments, researchers found that emigration can boost diversity when immigration rates surpass a specific threshold.
  • They confirmed that higher immigration rates can weaken fast-growing species and promote diversity, while also discovering that various factors like species pool size, growth rate, and interactions among species influence the immigration threshold.
View Article and Find Full Text PDF

Membrane transporters are proteins that mediate the entry and exit of substances through the plasma membrane and organellar membranes and are capable of recognizing and binding to specific substances, thereby facilitating substance transport. Membrane transporters are divided into different types, e.g.

View Article and Find Full Text PDF

In microbial systems, a metabolic pathway can be either completed by one autonomous population or distributed among a consortium performing metabolic division of labor (MDOL). MDOL facilitates the system's function by reducing the metabolic burden; however, it may hinder the function by reducing the exchange efficiency of metabolic intermediates among individuals. As a result, the function of a community is influenced by the trade-offs between the metabolic specialization and versatility of individuals.

View Article and Find Full Text PDF
Article Synopsis
  • * Recent advancements focus on near-infrared (NIR) iridium(III) complexes, which improve signal clarity and tissue penetration for better diagnostic and therapeutic uses.
  • * The review explores different types of NIR iridium(III) complexes and discusses their potential, along with the challenges they face in targeted detection and therapy.
View Article and Find Full Text PDF
Article Synopsis
  • - The study investigates microbial communities in petroleum reservoirs under high-pressure conditions, focusing on methanogenic and sulfate-reducing environments using production water from the Jilin Oilfield in China.
  • - A 90-day incubation revealed key microbial groups, with methanogenic conditions dominated by Firmicutes and unique methanogens, while sulfate-reducing communities were mostly Firmicutes and other candidate taxa important for nutrient exchange.
  • - The research highlights the importance of microbial interactions and metabolic roles in petroleum degradation, suggesting that high-pressure conditions can uncover previously overlooked microbial functions, often referred to as "microbial dark matter."
View Article and Find Full Text PDF
Article Synopsis
  • High pH levels in ecological concrete can hinder plant growth, prompting the development of a new device combining a microbial film and a transverse grouting film to address this issue.
  • The device improves the effectiveness of microbial bacteria recycling and solves problems related to grouting port blockages, while maintaining the compressive strength of the concrete.
  • Test results indicate that the new microbial grouting film significantly lowers the pH levels of ecological concrete to around 8 after 56 days, providing both environmental and economic advantages for concrete development.
View Article and Find Full Text PDF

Ferroptosis is a recently identified form of regulated cell death that plays a crucial role in tumor suppression. In this study, we found that F2 (the gene encoding thrombin) was strongly upregulated in breast cancer (BRCA, TCGA Study Abbreviations) compared with normal samples and that lower F2 levels were associated with poorer prognosis in breast cancer patients. Thrombin induces ferroptosis in triple-negative breast cancer (TNBC) cells by activation of cytosolic phospholipase A2α (cPLA2α) activity to increase the release of arachidonic acid (AA).

View Article and Find Full Text PDF

The deleterious effects of drought stress have led to a significant decline in vegetable production, ultimately affecting food security. After sensing drought stress signals, vegetables prompt multifaceted response measures, eventually leading to changes in internal cell structure and external morphology. Among them, it is important to highlight that the changes, including changes in physiological metabolism, signal transduction, key genes, and hormone regulation, significantly influence drought stress tolerance in vegetables.

View Article and Find Full Text PDF

Coarse-grained materials are widely accepted to display the highest strain hardening and the best tensile ductility. We experimentally report an attractive strain hardening rate throughout the deformation stage at 77 kelvin in a stable single-phase alloy with gradient dislocation cells that even surpasses its coarse-grained counterparts. Contrary to conventional understanding, the exceptional strain hardening arises from a distinctive dynamic structural refinement mechanism facilitated by the emission and motion of massive multiorientational tiny stacking faults (planar defects), which are fundamentally distinct from the traditional linear dislocation-mediated deformation.

View Article and Find Full Text PDF