TKTL1 is a crucial regulatory enzyme in the pentose phosphate pathway (PPP) and plays a significant role in energy synthesis. It is expressed in various tumour tissues, with its expression level closely associated with tumour invasion, metastasis and prognosis. Recent studies utilising proteomic analysis and other methods have highlighted the noteworthy expression of the TKTL1 gene in germ cells, particularly in spermatogonia and ovarian cells.
View Article and Find Full Text PDFThe transcription factor promyelocytic leukemia zinc finger (PLZF, also known as ZBTB16) is critical for the self-renewal of spermatogonial stem cells (SSCs). However, the function of PLZF in SSCs is not clear. Here, we found that PLZF acted as an epigenetic regulator of stem cell maintenance and self-renewal of germ cells.
View Article and Find Full Text PDFSource-separated urine is a readily accessible nutrients dense waste stream that can be used to recover nitrogen and hydrogen. In the research, the microbial electrochemical gas-permeable membrane system (MEGS) is creatively introduced for urine treatment in removing organics, recovering the total ammonia nitrogen and high-value product of hydrogen (H) as well as ammonium sulfate ((NH)SO). MEGS can simultaneously realize the functions of H recovery, in-situ efficient alkali production at the cathode, and the efficient absorption capacity of the gas-permeable membrane (GPM).
View Article and Find Full Text PDFSource-separated urine has been regarded as a precious treasure on account of its rich nitrogen content and is suitable for fertilizer production. In this study, a novel bioelectrical coupling with hydrophobic gas permeable tube system (BGTS) was developed to treat urine, for removing organic matter, and recover nitrogen as value-added products in the form of nitrogen fertilizer. In the presence of the electric field, the hydrolysis process of urea in the anode chamber was accelerated, and the NH driven by electric field force and concentration difference reached the cathode through the cation exchange membrane.
View Article and Find Full Text PDFElectroactive biofilm (EAB) has been considered as the core determining electricity generation in microbial fuel cells (MFCs), and its spatial structure regulation for enhanced activity and selectivity is of great concern. In this study, iron phthalocyanine (FePc) was introduced into a carbon cloth (CC) electrode, aiming at improving the affinity between the anode and outer membrane c-type cytochromes (OM c-Cyts) and achieving a highly active EAB. The FePc modified CC anode (FePc-CC) effectively improved the viability of EAB and enriched the Geobacter species up to 44.
View Article and Find Full Text PDFTo achieve a membrane cathode with excellent performance, iron-porphyrin (Fe(por)) was doped to boost the catalytic and permeability properties in microbial fuel cell (MFC). The membrane cathode with the optimal 0.05 g of Fe(por) (denoted as Fe(por)-0.
View Article and Find Full Text PDFMembrane filtration electrode based microbial fuel cell provides a promising route to simultaneously recover energy and produce high-quality effluent during water treatment. Enhancing effluent quality and oxygen reduction reaction (ORR) activity of the membrane electrode still remains a major challenge. In this study, filtration types of membrane electrodes with Prussian blue (PB) doping and PVDF-PVC-PEG triblock copolymers were prepared by a simple phase inversion fabrication process.
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