Synopsis of recent research by authors named "Xiaole Xu"
- XiaoLe Xu's recent research primarily focuses on molecular mechanisms related to environmental pollutants, cancer biology, and epigenetic factors, with studies investigating the effects of exposure to carbon black nanoparticles and benzo(a)pyrene on cellular transformation and maternal health.
- Xu has explored innovative approaches to drug design, particularly in targeting immune checkpoints like PD-L1, and optimizing multi-site drug interactions for SARS-CoV-2 therapeutic strategies, emphasizing the role of protein binding cooperativity and kinetic analysis.
- The author's work also delves into olfactory dysfunction as an early marker for Parkinson's disease and the implications of DNA modifications and protein mutations on gene expression and cellular processes, indicating a broad interest in both clinical and biochemical research areas.