Corneal ulcer development due to sintilimab-anlotinib combination therapy-induced dry eye: a case report.

Background: Programmed cell death-1 (PD-1) inhibitors and anti-angiogenic drugs have become a hotspot in research of anti-tumor programs; however, they can also cause some rare drug-related adverse reactions. Immune checkpoint inhibitors (ICIs) cause adverse reactions in the body, collectively known as immune-related adverse events (irAEs). Ocular side effects can occur in both targeted and immunotherapy patients, including dry eye, blurred vision, uveitis, conjunctivitis, retinopathy, or thyroid eye disease.

Qihuang Granule protects the retinal pigment epithelium from oxidative stress via regulation of the alternative complement pathway.

Background: Age-related macular degeneration (AMD) is a leading cause of vision loss in elderly people, and dry AMD is the most common type of AMD. Oxidative stress and alternative complement pathway activation may play essential roles in the pathogenesis of dry AMD. There are no available drugs for dry AMD.

The upper eyelid levator weakening procedure for the correction of severe cicatricial entropion caused by trachoma.

Background: Trachoma-induced upper eyelid cicatricial entropion (UCE) is a common and challenging eyelid disease. Surgeons have developed various surgical techniques to address UCE in the world. However, there are few reports about surgery for Chinese patients.

[Simultaneous determination of amino acids in food by capillary electrophoresis with indirect ultraviolet detection].

The characteristic of capillary electrophoresis (CE) with indirect ultraviolet (UV) detection of L-ornithine (Orn), L-proline (Pro) and L-glutamine (Gln) was investigated. A suitable electrolyte consists of 5 mmol/L sodium p-aminobenzene sulfonic acid-10 mmol/L KH2PO4 (pH 11.5) with UV detection at 254 nm.