Publications by authors named "Xiaolan Ke"
Endocr Connect
October 2023
Article Synopsis
- Protection of podocytes is crucial for slowing down diabetic nephropathy (DN), and the hormone GLP-1 has shown potential benefits for kidney health in diabetes models, though its specific effects on podocytes are not fully understood.
- In a study using a type 2 diabetes mouse model, liraglutide was found to significantly reduce podocyte injury after 14 weeks of treatment.
- The research revealed that liraglutide restores GLP-1 receptor expression in the kidneys and decreases inflammation and cell death related to a protein called NLRP3, suggesting a mechanism by which it protects podocytes in DN.
