FcγRIIb Exacerbates LPS-Induced Neuroinflammation by Binding with the Bridging Protein DAP12 and Promoting the Activation of PI3K/AKT Signaling Pathway in Microglia.

Introduction: This paper focuses on the expression and role of FcγRIIb in neuroinflammation, exploring the molecular mechanisms by which FcγRIIb interacts with the bridging protein DAP12 to regulate the PI3K-AKT signaling pathway that promote neuroinflammation and aggravate neuronal injury.

Methods: LPS-induced neuroinflammation models in vivo and in vitro were constructed to explore the role and mechanism of FcγRIIb in CNS inflammation. Subsequently, FcγRIIb was knocked down or overexpressed to observe the activation of BV2 cell and the effect on PI3K-AKT pathway.

Efficient CO Separation of Multi-Permselective Mixed Matrix Membranes with a Unique Interfacial Structure Regulated by Mesoporous Nanosheets.

A facile strategy to elevate gas separation performances of polymers is to introduce a versatile particle. In this study, the novel F-Ce nanosheets are synthesized, and then F-Ce is functionalized with 1-ethyl-3-methylimidazole thiocyanate (ionic liquids, ILs), obtaining multifunctional f-F-Ce nanosheets by the facile and environment-friendly methods. The multifunctional f-F-Ce nanosheets are incorporated into the Pebax (Pebax 1657) matrix to fabricate mixed matrix membranes (MMMs) for efficient CO separation.

Treatment of Ni-EDTA containing wastewater by electrocoagulation using iron scraps packed-bed anode.

The unique electrocoagulator proposed in this study is highly efficient at removing Ni-EDTA, providing a potential remediation option for wastewater containing lower concentrations of Ni-EDTA (Ni ≤ 10 mg L). In the electrocoagulation (EC) system, cylindrical graphite was used as a cathode, and a packed-bed formed from iron scraps was used as an anode. The results showed that the removal of Ni-EDTA increased with the application of current and favoured acidic conditions.

Pd/RGO modified carbon felt cathode for electro-Fenton removing of EDTA-Ni.

Ethylenediaminetetraacetic acid (EDTA) forms stable complexes with toxic metals such as nickel due to its strong chelation. The electro-Fenton (EF) process using a cathode made from palladium (Pd), reduced graphene oxide (RGO) and carbon felt, fed with air, exhibited high activities and stability for the removal of 10 mg L(-1) EDTA-Ni solution. Pd/RGO catalyst was prepared by one-pot synthesis; the scanning electron microscopy and X-ray diffraction analysis indicated nanoparticles and RGO were well distributed on carbon felt, forming three dimensional architecture with both large macropores and a mesoporous structure.