Spatial and temporal changes of ecosystem service value and its influencing mechanism in the Yangtze River Delta urban agglomeration.

As the mainstream and trend of urban development in China, deeply exploring the spatiotemporal patterns and influencing mechanisms of ecosystem service value in the Yangtze River Delta urban agglomeration is of great significance for achieving sustainable development goals in urban agglomerations. This paper uses the normalized difference vegetation index and net primary productivity as dynamic adjustment factors to measure the ecosystem service value of the Yangtze River Delta urban agglomeration and analyze its spatiotemporal evolution characteristics. Furthermore, a panel quantile regression model is constructed to explore the response differences of ecosystem service value at different levels to various influencing factors.

TRPV1 modulated NLRP3 inflammasome activation via calcium in experimental subarachnoid hemorrhage.

Neuroinflammation plays a key role in early brain injury (EBI) of subarachnoid hemorrhage (SAH), and NLRP3 inflammasome plays an important role in the development of neuroinflammation after SAH, but the mechanism of NLRP3 inflammasome activation after SAH is still unclear. TRPV1 is a non-selective calcium channel that is involved in the pathology of neuroinflammation, but its role in SAH has not been revealed. Our study showed that TRPV1 was significantly upregulated after SAH and was predominantly expressed in microglia/macrophages.

Spatial dynamics and influencing factors of carbon rebound effect in tourism transport: Evidence from the Yangtze-river delta urban agglomeration.

Economic efficiency gains in tourism are considered a crucial approach to reducing carbon emissions in the tourism sector, especially in tourism transport. However, as a significant source of carbon emissions from tourism activities, the total carbon emissions from tourism transport have not decreased proportionally to the reduction in the intensity, despite China's overall improvement in the tourism economic efficiency. This phenomenon is commonly known as the "rebound effect", which means that although technological progress can achieve emission reductions by efficiency improvement, but it can also indirectly stimulate socio-economic growth and creates new energy demands, results in expected emission reductions being offset by the additional economic growth effect.

Clinical Characteristics of Congenital Atresia of the Left Main Coronary Artery in 12 Children.

Background: Left main coronary artery atresia (LMCAA) is an extremely rare abnormality and only <100 cases have been reported worldwide. We describe the clinical manifestations, imaging features, prognosis, and treatments of LMCAA who were admitted in our department, which aimed to improve the clinical diagnosis and treatments of LMCAA in children.

Methods: A retrospective study identified 12 patients diagnosed with congenital left coronary artery atresia at Pediatric Heart Center of Beijing Anzhen Hospital from June 2010 to June 2019.