Yiqi Jiedu Xiaoying Decoction Improves Experimental Autoimmune Thyroiditis in Rats by Regulating Th17/Treg Cell Balance.

Background: Experimental autoimmune thyroiditis (EAT) is a widely used animal model to study the pathogenesis and treatment of autoimmune thyroid diseases. Yiqi Jiedu Xiaoying Decoction (YJXD) is a traditional Chinese medicine formula with potential immunomodulatory effects. In this study, we investigated the therapeutic effects of YJXD on EAT in rats and explored its underlying mechanisms.

Semi-Implicit Time Integration with Hessian Eigenvalue Corrections for a Larger Time Step in Molecular Dynamics Simulations.

In molecular dynamics simulations, the limited time step size has been a barrier to simulating long-time behaviors. Implicit time integration methods allow markedly larger time steps than the standard explicit time method, although they have major drawbacks such as overheads solving linear systems and instability of Newton iterations. To overcome these issues, we propose a semi-implicit time integration scheme, the semi-implicit Hessian correction (SimHec) scheme, for overdamped Langevin dynamics.

Deformable regions of interest with multiple points for tissue tracking in echocardiography.

By tracking echocardiography images more accurately and stably, we can better assess myocardial functions. In this paper, we propose a new tracking method with deformable Regions of Interest (ROIs) aiming at rational pattern matching. For this purpose we defined multiple tracking points for an ROI and regarded these points as nodes in the Meshfree Method to interpolate displacement fields.