Publications by authors named "Xiaojun Lyu"

A colorimetric chemosensor array based on an indicator displacement assay has achieved not only visualization of differences in hormone structures but also quantitative detection of sex hormones in their mixtures. Furthermore, the chemosensor array has allowed the detection of a steroid hormone in diluted human saliva.

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Background: Considering the adverse clinical consequences of pathologic tachycardia and the potential anxiety caused by physiological tachycardia in some heathy individuals, it is imperative to disseminate health information related to tachycardia for promotion in early diagnosis and appropriate management. YouTube has been increasingly used to access health care information. The aim of this study is to assess the quality and reliability of English YouTube videos focusing on tachycardia and further delve into strategies to enhance the quality of online health resources.

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We herein propose an approach to visualize the Menschutkin reaction at an interface between a self-assembled monolayer with nucleophilic properties and water containing alkyl halides. An organic field-effect transistor functionalized with a nucleophilic monolayer has detected alkylation depending on differences in the leaving group ability and the bulkiness of electrophilic alkyls.

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π-Conjugated polymers such as polythiophene provide intramolecular wire effects upon analyte capture, which contribute to sensitive detection in chemical sensing. However, inherent aggregation-induced quenching causes difficulty in fluorescent chemical sensing in the solid state. Herein, we propose a solid-state fluorescent chemosensor array device made of a paper substrate (PCSAD) for the qualitative and quantitative detection of metal ions.

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The development of chemical sensors has advanced due to an increase in demand; however, the potential of chemical sensors as devices to monitor organic reactions has not been revealed yet. Thus, we aim to propose a chemical sensor platform for facile monitoring of chemical reactions, especially at a solid-liquid interface. In this study, an extended-gate-type organic field-effect transistor (OFET) has been employed as a platform to detect chemical reactions at an interface between the extended-gate electrode and an aqueous solution.

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Background: In the diasporic eastern coastal region of China, leftover children are a unique group of children; their social adaptation challenges are more prominent due to transnational separation from parents. This study explores the relationship between parent-offspring communication and school adaptation among leftover children.

Methods: We administered questionnaires to 957 children from six schools in June and December of 2022.

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Herein, we propose a novel amphiphilic polythiophene-based chemosensor functionalized with a Zn(II)-dipicolylamine side chain (1  ⋅ Zn) for the pattern recognition of oxyanions. Optical changes in amphiphilic 1  ⋅ Zn can be induced by the formation of a random coil from a backbone-planarized structure upon the addition of target oxyanions, which results in blueshifts in the UV-vis absorption spectra and turn-on-type fluorescence responses. Dynamic behavior in a polythiophene wire and/or among wires could be a driving force for obtaining visible color changes, while the molecular wire effect is dominant in obtaining fluorescence sensor responses.

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A self-assembled chemosensor prepared using off-the-shelf materials has shown various fluorescence responses including ratiometric and simple ON-OFF switching profiles by adding different toxic metal ions. The unique fingerprint-like responses have been applied to pattern recognition of metal ions in river water for environmental analysis.

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Here, we propose a printed 96-well microtiter paper-based chemosensor array device (PCSAD) to simultaneously detect metal ions for river water assessment. Colorimetric chemosensors for metal ions have been designed based on molecular self-assembly using off-the-shelf catechol dyes and a phenylboronic acid (PBA) derivative. The colorimetric self-assembled chemosensors consisting of catechol dyes and a PBA derivative on a 96-well microtiter paper substrate demonstrated various color changes according to the disassembly of the ensembles by the addition of nine types of metal ions.

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We propose a printed 384-well microtiter paper-based fluorescent chemosensor array device (384-well microtiter PCAD) to simultaneously categorize and discriminate saccharides and sulfur-containing amino acids for food analysis. The 384-well microtiter PCAD requiring 1 μL/4 mm of each well can allow high-throughput sensing. The device embedded with self-assembled fluorescence chemosensors displayed a fingerprint-like response pattern for targets, the image of which was rapidly captured by a portable digital camera.

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Promoting technical change is an important driving force for promoting the sustainable development of urban economy and ecology; however, the technical change is not always neutral and technical change may has a certain direction. This paper uses the DEA-Malmquist index to measure the directed technical change of 280 cities in China from 2009 to 2019, and uses the DMSP/OLS night light data to characterize the urban economic development level. It uses the dynamic threshold regression model to analyze the impact of directed technical change on urban carbon footprint under different economic development levels.

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We herein report the quantitative detection of biogenic amines using a gold nanoparticle-based colorimetric chemosensor array for food analysis. The gold nanoparticles are functionalized with carboxylate derivatives, which capture target amines through hydrogen bonds and electrostatic interactions. The simultaneous discrimination of 10 amine derivatives was achieved by a linear discriminant analysis with a 100% correct classification based on the multi-colorimetric response pattern of structural differences.

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Herein, we report an extended-gate-type organic field-effect transistor (OFET) sensor for oxytocin. The fabricated OFET-based immunosensor has successfully detected oxytocin at a ppt level in human saliva with high recovery rates (96-102%). We believe our sensor would pave the way for the realization of portable sensors for healthcare monitoring.

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We herein report an organic field-effect transistor (OFET) based chemical sensor for multi-oxyanion detection with pattern recognition techniques. The oxyanions ubiquitously play versatile roles in biological systems, and accessing the chemical information they provide would potentially facilitate fundamental research in diagnosis and pharmacology. In this regard, phosphates in human blood serum would be a promising indicator for early case detection of significant diseases.

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We herein propose an easy-to-prepare mini-chemosensor array constructed by two-types of off-the-shelf coumarin dyes for simultaneous classification and quantification of sulfur-containing amino acids (SCAAs) (i.e., l-cysteine, l-cystine, l-homocysteine, glutathione, and glutathione disulfide).

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Introduction: Community resilience (CR) has gradually become a hot topic in uncertain times, especially in the last five years. The current study presents a systematic review based on content analysis to present a knowledge graph of CR research over the last 20 years.

Methods: We use an approach of Leximancer to conduct the content analysis to explore the intellectual foundations, research context, topics, and methods of CR literature based on 583 published studies.

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COVID-19 pandemic destroyed lives and the global economy, and in the wake left businesses struggling to re-open in urban China. The Chinese party-state implemented fiscal reforms targeted towards small businesses, however little research has evaluated business' understanding of policies and implementation, particular to the focus on rural migrant entrepreneurs. Therefore, we conducted an ethnographic case study including in-depth interviews to determine to what extent rural migrant micro-entrepreneurs understand and adopt COVID-19 business support policies at two retail markets in Shanghai amid a pandemic.

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Herein, a self-assembled colorimetric chemosensor array composed of off-the-shelf catechol dyes and a metal ion (i.e., Zn) has been used for the sulfur-containing amino acids (SCAAs; i.

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We report a paper-based chemosensor array device (PCSAD) for the quantitative detection of oxyanions including the herbicide glyphosate (GlyP) in aqueous media. The mechanism of the oxyanion detection relies on a coordination-binding-based sensor array. In this study, the competitive coordination binding among Zn , four catechol dyes, and seven oxyanions caused noticeable colour changes.

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Although work engagement as a positive organizational behavior has gained considerable achievements in recent years, there is still a lack of content research based on certain culture, job, and group characteristics. This study conducts a grounded theory research on work engagement by coding and analyzing the interview files from public servants working in the government located in Eastern China. The result shows a five-dimension construct of work engagement, which includes loyalty to the work, commitment to the working relationships, positive emotion, initiative action, and priority for mixed roles.

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Simple, rapid, and accurate detection methods for saccharides are potentially applicable to various fields such as clinical and food chemistry. However, the practical applications of on-site analytical methods are still limited. To this end, herein, we propose a 96-well microtiter plate made of paper as a paper-based chemosensor array device (PCSAD) for the simultaneous classification of 12 saccharides and the quantification of fructose and glucose among 12 saccharides.

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We investigated a host-guest complex between cucurbit[7]uril and malachite green, and its effect on the toxicity to human liver cells. The host-guest complexation was evaluated by a UV/vis titration and electrospray-ionization mass spectrometry. Interestingly, the host-guest complex resulted in remarkable suppression of the toxicity of malachite green in its practical concentration range (ca.

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An artificial tongue that detects astringent components for a comprehensive evaluation of taste has not been established to date. Herein, we first propose fluorescent polythiophene (PT) derivatives (S1-S3) modified with 3-pyridinium boronic acid as supramolecular chemosensors for wine components including astringent procyanidin C1. After numerous attempts for the synthetic conditions, more than 95 mol % of the PT unit was modified with the pyridinium boronic acid moiety.

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A novel fluorescence chemosensor array composed of pyrenylboronic acid-based probes for multi- anion detection has been developed. The pyrenylboronic acid derivatives showed fluorescence quenching or enhancement due to photoinduced electron transfer originating from anion binding. The recognition ability was assessed by fluorescence titrations and electrospray ionization mass spectrometry.

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Objectives: Obstructive sleep apnea (OSA) is a disease with high prevalence, which reportedly influences our eyes, brain, cardiovascular system and endocrine metabolism system. Much of these symptoms are thought to be associated with damage to the brain. However, the basic neural pathophysiologic mechanism underlying these deficits is unclear.

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