Publications by authors named "Xiaojue Hu"
Psychedelic Harm Reduction and Integration: A Transtheoretical Model for Clinical Practice.
Curr Top Behav Neurosci
December 2024
Article Synopsis
- Psychedelic Harm Reduction and Integration (PHRI) is a clinical model designed to help clients prepare for and integrate psychedelic experiences in a therapeutic context without administering psychedelics.
- It combines elements from various therapeutic approaches, including harm reduction psychotherapy and mindfulness techniques, to empower clients while addressing both difficult and positive experiences.
- The model focuses on principles like non-directive approaches and emotional awareness, aiming to facilitate lasting positive change while minimizing potential risks associated with psychedelics.
Importance: Psilocybin shows promise as a treatment for major depressive disorder (MDD).
Objective: To evaluate the magnitude, timing, and durability of antidepressant effects and safety of a single dose of psilocybin in patients with MDD.
Design, Setting, And Participants: In this phase 2 trial conducted between December 2019 and June 2022 at 11 research sites in the US, participants were randomized in a 1:1 ratio to receive a single dose of psilocybin vs niacin placebo administered with psychological support.