Lignin-Based N-Carbon Dots Anchoring NiCoS/Graphene Hydrogel Exhibits Excellent Performance as Anodes for Hybrid Supercapacitor.

A NiCoS/N-CDs/RGO ternary composite hydrogel was prepared via a one-step hydrothermal method, utilizing lignin-based nitrogen-doped carbon dots as a bridge connecting NiCoS and graphene. The specific capacitance of NiCoS/N-CDs/RGO significantly outperforms that of the GH and NiCoS/RGO electrodes, achieving 1050 F g. The 3D mesh porous hydrogel structure mitigates NiCoS nanoparticle aggregation, providing a larger specific surface area for enhanced charge storage.

High-Sensitivity Enzyme-Free Fluorescence Probe Based on CRISPR/Cas13 and the Isothermal Amplification Strategy for Axl Sensing.

Axl is an important receptor tyrosine protein kinase that plays a key role in the development and progression of various diseases, such as cancer and inflammation. Developing a highly sensitive Axl detection method can help improve accuracy, better address-specific clinical needs, and guide personalized treatment. In this study, a CHA-CRISPR/Cas13 fluorescence probe was established using Axl-specific aptamers as a mediator to displace the polynucleotide chain (TA).

Facile design of structurally robust, highly conductive and well-flexible hybrid film based on MXene, cellulose nanofiber and poly (3,4-ethylenedioxythiphoenes):polystyrene sulfonate for supercapacitors.

Robust, conductive and flexible electrode materials have been the focus of attention in portable, wearable electronics. However, it is still a significant challenge to achieve synergistic development of multiple properties simultaneously. Herein, we propose a combination of microscale design and nanostructures strategy to prepare MXene/cellulose nanofiber-poly (3,4-ethylenedioxythiphoenes):polystyrene sulfonate (TiCT/CNF-PEDOT:PSS, TC-P) hybrid film by a simple in-situ polymerization and vacuum filtration process.

High stretchable and tough xylan-g-gelatin hydrogel via the synergy of chemical cross-linking and salting out for strain sensors.

Stretchable and tough hydrogels have been extensively used in tissue engineering scaffolds and flexible electronics. However, it is still a significant challenge to prepare hydrogels with both tensile strength and toughness by utilizing xylan, which is abundant in nature. Herein, we present a novel hydrogel of carboxymethyl xylan(CMX) graft gelatin (G) and doped with conductive hydroxyl carbon nanotubes (OCNT).

Sodium carboxymethylcellulose/MXene/zeolite imidazolium framework-67-derived 3D porous carbon aerogel for high-performance asymmetric supercapacitors.

Herein, we propose a carbon/TiO/CoO (CTC) composite carbon aerogel with a 3D porous conductive network structure derived from sodium carboxymethylcellulose (CMC)/Mxene (TiCT)/zeolite imidazolium framework-67 (ZIF-67). Among them, CMC is used as the carbon skeleton, which can reduce the powdering caused by volume change and improve the cycle stability. TiCT acts as the conductive agent and dispersant for ZIF-67, exposing more reactive sites while constructing fast conductive channels to enhance electrochemical performance.

Artificial intelligence-based diagnosis of standard endoscopic ultrasonography scanning sites in the biliopancreatic system: a multicenter retrospective study.

Background: There are challenges for beginners to identify standard biliopancreatic system anatomical sites on endoscopic ultrasonography (EUS) images. Therefore, the authors aimed to develop a convolutional neural network (CNN)-based model to identify standard biliopancreatic system anatomical sites on EUS images.

Methods: The standard anatomical structures of the gastric and duodenal regions observed by EUS was divided into 14 sites.

Carboxymethylcellulose/poly(3,4-ethylenedioxythiophene):polystyrene sulfonate membrane after dimethyl sulfoxide treatment for flexible and high electrochemical performance asymmetric supercapacitors.

As the requirements for wearable electronic devices continue to increase, the development of bendable and foldable supercapacitors is becoming critical. However, it is still challenging to design free-standing electrodes with flexibility and high electrical conductivity. Herein, using carboxymethylcellulose (CMC) as the biological template and poly(3,4-ethylenedioxythiophene):polystyrene sulfonate (PEDOT:PSS) as the electroactive material, a flexible CMC/PEDOT:PSS membrane with a cross-linked mesh structure was firstly synthesized by a facile in-situ polymerization and vacuum filtration process.

Flexible and alternately layered high electrochemical active electrode based on MXene, carboxymethylcellulose, and carbon nanotube for asymmetric micro-supercapacitors.

Recent studies have shown that Ti-based MXene has great potential for electrochemical energy storage applications, including Li-ion batteries and micro-supercapacitors. However, self-stacking and weak interlayer interactions lead to poor electrochemical properties. Herein, a simple one-step vacuum filtration method was used to prepare a MXene/carboxymethylcellulose/carbon nanotube (TiCT/CMC/CNT) hybrid membrane.

Advances in the application of molecular diagnostic techniques for the detection of infectious disease pathogens (Review).

Infectious diseases are a major global cause of morbidity and mortality, seriously affecting public health and socioeconomic stability. Since infectious diseases can be caused by a wide variety of pathogens with similar clinical manifestations and symptoms that are difficult to accurately distinguish, selecting the appropriate diagnostic techniques for the rapid identification of pathogens is crucial for clinical disease diagnosis and public health management. However, traditional diagnostic techniques have low detection rates, long detection times and limited automation, which means that they do not meet the requirements for rapid diagnosis.

Enrichment of miR-17-5p enhances the protective effects of EPC-EXs on vascular and skeletal muscle injury in a diabetic hind limb ischemia model.

Background/aims: Diabetes mellitus (DM) is highly susceptible to diabetic hind limb ischemia (DHI). MicroRNA (MiR)-17-5p is downregulated in DM and plays a key role in vascular protection. Endothelial progenitor cell (EPC)-released exosomes (EPC-EXs) contribute to vascular protection and ischemic tissue repair by transferring their contained miRs to target cells.

Free-standing reduced graphene oxide/carboxymethylcellulose-polyaniline (RGO/CMC-PANI) hybrid film electrode for high-performance asymmetric supercapacitor device.

This work demonstrates a facile and effective strategy for the preparation of a reduced graphene oxide/carboxymethylcellulose-polyaniline (RGO/CMC-PANI) hybrid film electrode. Specifically, through the hydrogen bonding interaction between -OH of CMC molecules and -NH of aniline monomer, PANI grows in an ordered manner on the surface of CMC, which effectively alleviates the structural collapse of PANI during the continuous charge/discharge process. After compounding with RGO, CMC-PANI bridges adjacent RGO sheets to form a complete conductive path, and opens the gap between RGO sheet layers to obtain fast ion channels.

MiR-17-5p Mediates the Effects of ACE2-Enriched Endothelial Progenitor Cell-Derived Exosomes on Ameliorating Cerebral Ischemic Injury in Aged Mice.

Aging is one of the key mechanisms of vascular dysfunction and contributes to the initiation and progression of ischemic stroke (IS). Our previous study demonstrated that ACE2 priming enhanced the protective effects of exosomes derived from endothelial progenitor cells (EPC-EXs) on hypoxia-induced injury in aging endothelial cells (ECs). Here, we aimed to investigate whether ACE2-enriched EPC-EXs (ACE2-EPC-EXs) could attenuate brain ischemic injury by inhibiting cerebral EC damage through their carried miR-17-5p and the underlying molecular mechanisms.

Establishment and Evaluation of Recombinant Expression of HCV Transmembrane Protein (p7) and Detection of Anti-p7 Antibody in Serum of HCV-Infected Patients by Chemiluminescence.

Objective: Our aim was to establish a chemiluminescence method for detecting anti-transmembrane protein (p7) antibody in the serum of patients with hepatitis C virus (HCV) infection.

Methods: The p7 gene was amplified by polymerase chain reaction using the plasmid PUC-p7 containing the p7 nucleic acid sequence of the HCV 1b genotype as the template, and recombinant plasmid pGEX-KG-p7 was constructed. After p7 fusion, the protein was induced and expressed in the prokaryote, extracted, and purified; the anti-p7 antibody detection kit was prepared, and its efficacy was evaluated.

Carboxymethylcellulose-polyaniline/carbon nanotube (CMC-PANI/CNT) film as flexible and highly electrochemical active electrode for supercapacitors.

Herein, we demonstrate a flexible, structural robust and highly electrochemical active film electrode based on evenly distributed carboxymethylcellulose-polyaniline/carbon nanotube (CMC-PANI/CNT) for supercapacitors. In this process, vertically aligned PANI nanoparticles grow in an orderly manner on CMC fibers. The highly dispersed CNT nanomaterials are then introduced by simple layer-by-layer assembly, eventually forming an interwoven network structure.

In situ growth of chrysanthemum-like NiCoS on MXenes for high-performance supercapacitors and a non-enzymatic HO sensor.

In this work, we developed a novel strategy to couple chrysanthemum-like NiCoSin situ-grown MXene hybrids into a three-dimensional (3D) sandwich architecture hybrid as an electrode material for high-performance asymmetric supercapacitors and non-enzymatic HO sensors. In the 3D sandwich architecture hybrid, the NiCoS particles were encapsulated by MXene layers, which enhanced the interlayer space of MXene, significantly improving the electrochemical properties. In particular, the MXene/NiCoS 1 : 2 electrode achieved a specific capacitance of 1266 F g at 0.

The effects of deposition time and current density on the electrochemical performance of flexible and high-performance MnO@PFG composite electrodes.

A novel composite electrode has been fabricated by the direct deposition of MnO onto graphene networks surrounding a paper fiber (PFG). The paper fiber between graphene sheets could be used as a flexible substrate for MnO nanoparticles, and the microscopic morphologies and electrochemical performances of the MnO@PFG electrodes were tuned regulating the deposition current densities and deposition times. 3D graphene on PFG served as a highly conductive backbone with a high surface area for the deposition of the MnO nanoparticles, which provided high accessibility to electrolyte ions for shortening the diffusion paths.

Self-assembly of flexible graphene hydrogel electrode based on crosslinked pectin-cations.

Pectin, natural polysaccharide biopolymer, was chelated with cations (Mg/Ca) to form an interwoven framework. Herein, the graphene hydrogel electrodes were self-assembled by the synergistic effects of pectin-cations. The optimum combination proportion was determined, the Mg/Ca-pectin matrix cross-linked graphene hydrogel (Mg/Ca-PGH) electrodes exhibited a large specific capacitance of about 839.

High-performance MnO-deposited graphene/activated carbon film electrodes for flexible solid-state supercapacitor.

High theoretical capacitance of MnO nanoparticles were successfully electrodeposited on the conductive graphene/activated carbon (GN/AC) composite film, and the urchin type MnO microspheres were controlled by adjusting the electro-deposition reaction times. The GN/AC/MnO-1200s composite electrodes exhibited a maximum specific capacitance of 1231 mF/cm (MnO loading mass of 7.65 mg/cm and the mass specific capacitance of 123 F/g) at a current density of 0.

Automated multi-filtration cleanup with nitrogen-enriched activated carbon material as pesticide multi-residue analysis method in representative crop commodities.

An automated multi-filtration cleanup (Auto m-FC) method with nitrogen-enriched activated carbon material based on modified QuEChERS (quick, easy, cheap, effective, rugged, and safe) extracts was developed. It was applied to pesticide multi-residue analysis in six representative crop commodities. The automatic device was aimed to improve the cleanup efficiency and reduce manual operation workload in cleanup step.

[The influence of reference data noise on the NIR prediction results].

This article used hemicelluloses content in acacia spp. wood as a case study to demonstrate the influence of noise in the reference data on the results of NIR calibration model. The results indicated that the accuracy of NIR calibration model was affected by the reference data noise.

Influence of polymorphism of glutathione S-transferase T1 on Chinese infertile patients with varicocele.

To investigate the influence of glutathione S-transferase T1 (GSTT1) gene polymorphism on Chinese infertile patients with varicocele, 63 infertile patients with varicocele and 54 healthy fertile controls were recruited in this case-control study. Our results show that oxidative damage may be the cause of infertility in patients with varicocele, and GSTT1 null genotype predisposes to over oxidative damage to spermatocytes of infertile patients with varicocele.

Genetic polymorphism of glutathione S-transferase T1 gene and susceptibility to idiopathic azoospermia or oligospermia in northwestern China.

Aim: To investigate the association of glutathione S-transferase T1 (GSTT1) gene polymorphism in patients with idiopathic azoospermia or oligospermia in the northwestern China population.

Methods: In the case-control study, GSTT1 genotypes were identified by multiplex polymerase chain reaction (PCR) with peripheral blood DNA samples from 78 patients with idiopathic azoospermia, 103 patients with idiopathic oligospermia and 156 age-matched controls with normal sperm concentration and motility, according to the criteria adapted from World Health Organization guidelines. All of the patients and controls were from northwestern China.

[Genetic polymorphism of glutathione S-transferase T1 associated with idiopathic azoospermia and oligospermia].

Objective: To investigate the association of glutathioneS-transferase T (GSTT1) gene polymorphism with azoospermia and oligospermia.

Methods: Semen samples from 34 patients with idiopathic azoospermia, 40 patients with idiopathic oligospermia and 53 healthy controls with normal sperm concentration and motility were assessed according to the standards of WHO. The GSTT1 genotypes were identified by multiplex polymerase chain reaction (PCR) with peripheral blood DNA samples.