Publications by authors named "Xiaojuan Ai"
Rice bran is an industrial byproduct that exerts several bioactivities despite its limited bioavailability. In this study, rice bran fermented with MF423 (FLRB) had enhanced antidiabetic effects both and . FLRB could increase glucose consumption and decrease lipid accumulation in insulin resistant HepG2 cells.
View Article and Find Full Text PDFMicroRNA (miRNA) expression is perturbed in various diseases. Herein, we have aimed to develop a novel and rapid fluorescence-based assay for detecting microRNA-21 (miR-21) activity based on FAM molecular signal amplification and graphene oxide (GO) quenching. In this system, a single stranded DNA (ssDNA) with a phosphate group at the 5'-end is labeled with a FAM molecular label at the 3'-end.
View Article and Find Full Text PDFArticle Synopsis
- Lung cancer is the leading cause of cancer death globally, with non-small cell lung cancer (NSCLC) making up 85% of cases, traditionally treated with chemotherapy, which often has limited effectiveness.
- Recent advancements in molecular targeting therapies have improved treatment outcomes for NSCLC by specifically targeting cancer cells while minimizing damage to normal tissues.
- This review highlights various targeted treatments, discusses challenges like drug resistance, and aims to guide clinicians and researchers in making more informed therapeutic decisions.