Publications by authors named "Xiaoju Ding"
Article Synopsis
- A special protein called TDO2 is found in higher amounts in bladder cancer tissues and makes it harder for patients to survive.
- TDO2 helps cancer cells grow and spread and makes them less sensitive to a common medicine called cisplatin that is used to treat cancer.
- New research shows that blocking TDO2 can slow down cancer growth and make treatments work better, which could help people with bladder cancer.
Article Synopsis
- This study compares traditional radiographic urethrography (RUG) with magnetic resonance urethrography (MRU) for diagnosing iatrogenic bladder outlet obstruction (BOO) and examines the outcomes of laparoscopic modified Y-V plasty based on MRU findings.
- The research involved 31 patients with obliteration segments of 2 cm or less, finding that MRU provided more accurate measurements of obstruction compared to conventional methods, aiding in the surgical planning.
- Postoperative results showed a high success rate for urethral patency (90.3%) and a relatively low rate of urinary incontinence (87.1%), indicating that the laparoscopic technique is effective and may reduce complications associated with BOO
Purpose: GPR120 has been reported to ameliorate inflammation in diabetes and diabetic complications. In this study, GW9508, the GPR120 agonist, was utilized in human retinal microvascular endothelial cells (HRMECs) exposed to high glucose (HG) to investigate the involvement of GPR120 in cellular viability and apoptosis as well as the association with the NLRP3 inflammasome.
Methods: The expression of GPR120 in HRMECs cultured under HG was firstly detected by Western blotting.
Icariside II (ICA II) is used in erectile dysfunction treatment. Adipose tissue-derived stem cells (ADSCs) are efficient at improving erectile function. This study aimed to explore the action mechanism of ADSCs in improving erectile function.
View Article and Find Full Text PDFBisphenol A (BPA) acts as xenoestrogen and has a great impact on disorders of human reproductive system. However, the mechanism through which BPA can affect human testicular function remains to be identified. GPR30 is a novel membrane estrogen receptor with high-affinity and low-capacity binding to estrogens.
View Article and Find Full Text PDF[Application of gene knockout technology in spermatogenesis-associated gene study].
Zhonghua Nan Ke Xue
September 2014
The gene approach to the pathogenesis of male infertility may bring about some strategies for the diagnosis and manage of the condition. Gene knockout technology is the mainstream method currently used in the study of gene function. Screening and identification of testis-specific genes and insights into their features and functions in spermatogenesis are significant for a further understanding of testicular functions and searching for new therapeutic targets for male reproductive disorders.
View Article and Find Full Text PDFA high performance liquid chromatographic (HPLC) method was developed for the simultaneous determination of seven effective components in Houpuwenzhong capsules. The separation was performed on a Scienhome C18 column (250 mm x 4.6 mm, 5 microm) with methanol-acetonitrile-0.
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