The causality between gut microbiota and functional dyspepsia: A two-sample Mendelian randomization analysis.

To investigate the potential link between gut microbiota and functional dyspepsia (FD). Genome-wide association studies (GWAS) of gut microbiota and FD were used in Mendelian randomization (MR) research. Using the GWAS of 18,340 people, instrumental variables related to gut microbiota as an exposure factor were identified.

Efficient Photothermal Catalytic Oxidation Enabled by Three-Dimensional Nanochannel Substrates.

Photothermal catalysis exhibits promising prospects to overcome the shortcomings of high-energy consumption of traditional thermal catalysis and the low efficiency of photocatalysis. However, there is still a challenge to develop catalysts with outstanding light absorption capability and photothermal conversion efficiency for the degradation of atmospheric pollutants. Herein, we introduced the CoO layer and Pt nanoclusters into the three-dimensional (3D) porous membrane through the atomic layer deposition (ALD) technique, leading to a Pt/CoO/AAO monolithic catalyst.

Improved Interface Construction on Anode and Cathode for Na-Ion Batteries Using Ultralow-Concentration Electrolyte Containing Dual-Additives.

Compared with Li, Na with a smaller stokes radius has faster de-solvation kinetics. An electrolyte with ultralow sodium salt (0.3 M NaPF) is used to reduce the cell cost.

Changing epidemiologic patterns of typhus group rickettsiosis and scrub typhus in China, 1950-2022.

Objectives: We conducted a systematic analysis of the notifiable rickettsial diseases in humans in China during 1950-2022.

Methods: We utilized descriptive statistics to analyze the epidemiological characteristics, clinical manifestations, and diagnostic characteristics of typhus group rickettsiosis (TGR) and scrub typhus (ST) cases.

Results: Since the 1950s, there have been variations in the incidence rate of TGR and ST in China, with a downtrend for TGR and an uptrend for ST.

Molecular Detection of Tick-Borne Bacterial and Protozoan Pathogens in (Acari: Ixodidae) Ticks from Free-Ranging Domestic Sheep in Hebei Province, China.

Ticks and tick-borne pathogens significantly threaten human and animal health worldwide. is one of the dominant tick species in East Asia, including China. In the present study, 646 ticks were collected from free-ranging domestic sheep in the southern region of Hebei Province, China.

Diversity of Rickettsiales bacteria in five species of ticks collected from Jinzhai County, Anhui Province, China in 2021-2022.

The order Rickettsiales in the class Alphaproteobacteria comprises vector-borne pathogens of both medical and veterinary importance. Ticks, as a group, are second only to mosquitoes as vectors of pathogens to humans, playing a critical role in the transmission of rickettsiosis. In the present study, 880 ticks collected from Jinzhai County, Lu'an City, Anhui Province, China in 2021-2022 were identified as belonging to five species from three genera.

Quenching-Induced Defect-Rich Platinum/Metal Oxide Catalysts Promote Catalytic Oxidation.

Enhancing oxygen activation through defect engineering is an effective strategy for boosting catalytic oxidation performance. Herein, we demonstrate that quenching is an effective strategy for preparing defect-rich Pt/metal oxide catalysts with superior catalytic oxidation activity. As a proof of concept, quenching of α-FeO in aqueous Pt(NO) solution yielded a catalyst containing Pt single atoms and clusters over defect-rich α-FeO (Pt/FeO-Q), which possessed state-of-the-art activity for toluene oxidation.

Legionnaires' Disease in China Caused by Corby.

is an intracellular pathogen causing pneumonia in humans. In February 2022, Legionnaires' disease caused by strain Corby in a patient with lung adenocarcinoma was identified for the first time in China. This paper includes the case report and phenotypic and genomic analysis of the Corby (ICDC) strain.

Clinical Forms of Japanese Spotted Fever from Case-Series Study, Zigui County, Hubei Province, China, 2021.

We report a case-series study of 5 patients with Japanese spotted fever from the Three Gorges Area in China, including 1 fatal case. Seroprevalence of Rickettsia japonica was ≈21% among the local population. Our report highlights the emerging potential threat to human health of Japanese spotted fever in the area.

Infection in Fever and Thrombocytopenia Patients - Anhui Province, China, 2021.

What Is Already Known About This Topic?: The genus contains seven recognized bacterial species, mainly transmitted by tick bites. The two species, and , are known commonly to cause diseases in humans.

What Is Added By This Report?: was initially thought to be only an animal agent until the first patient case was reported in 2019.

Quenching-induced surface modulation of perovskite oxides to boost catalytic oxidation activity.

Quenching is a powerful method for modulating surface structures of metal oxide nanocatalysts to achieve high catalytic oxidation activities, but it is still challenging. Herein, a catalyst of ultrafine CoO nanoparticles decorated on Co-doped LaMnO (CoO/LaCoMnO) is synthesized via one-step quenching perovskite-type LaMnO nanocatalyst into an aqueous solution of cobalt nitrate, which exhibits significantly improved catalytic performance with toluene (1000 ppm) conversion of 90% at 269 °C under the gas hourly space velocity of 72000 mL g h. The high catalytic activity correlates with large surface area, abundant oxygen vacancies and good reducibility.

The elevation of miR-185-5p alleviates high-fat diet-induced atherosclerosis and lipid accumulation and via SREBP2 activation.

Objective: SREBP2, a member of the family, is a primary regulator of lipid metabolism. In recent years, an increasing number of studies have suggested that miRNAs regulate lipid metabolism-related genes. It was speculated in this study that miRNAs may be implicated in the regulation of lipid accumulation in macrophages by SREBP2 protein.

Comprehensive analysis of N6-methylandenosine regulators and m6A-related RNAs as prognosis factors in colorectal cancer.

Colorectal cancer (CRC) is one of the most common malignancies and has been a leading cause of cancer-related death worldwide in recent years. N6-methyladenosine (m6A) methylation is the most abundant epigenetic modification of various types of RNAs, and it plays a vital role in promoting cancer development. Here, we obtained SNV and transcriptome data of CRC from The Cancer Genome Atlas (TCGA).

A Hydrothermally Stable Single-Atom Catalyst of Pt Supported on High-Entropy Oxide/AlO: Structural Optimization and Enhanced Catalytic Activity.

A catalyst with high-entropy oxide (HEO)-stabilized single-atom Pt can afford low-temperature activity for catalytic oxidation and remarkable durability even under harsh conditions. However, HEO is easy to harden during sintering, which results in a few defective sites for anchoring single-atom metals. Herein, we present a sol-gel-assisted mechanical milling strategy to achieve a single-atom catalyst of Pt-HEO/AlO.

Activating Metal Oxides Nanocatalysts for Electrocatalytic Water Oxidation by Quenching-Induced Near-Surface Metal Atom Functionality.

Developing a reliable strategy for the modulation of the texture, composition, and electronic structure of electrocatalyst surfaces is crucial for electrocatalytic performance, yet still challenging. Herein, we develop a facile and universal strategy, quenching, to precisely tailor the surface chemistry of metal oxide nanocatalysts by rapidly cooling them in a salt solution. Taking NiMoO nanocatalysts an example, we successfully produce the quenched nanocatalysts offering a greatly reduced oxygen evolution reaction (OER) overpotential by 85 mV and 135 mV at 10 mA cm and 100 mA cm respectively.

Identification of prognostic immune-related gene signature associated with tumor microenvironment of colorectal cancer.

Background: The tumor microenvironment (TME) has significantly correlation with tumor occurrence and prognosis. Our study aimed to identify the prognostic immune-related genes (IRGs)in the tumor microenvironment of colorectal cancer (CRC).

Methods: Transcriptome and clinical data of CRC cases were downloaded from TCGA and GEO databases.

Recent Progress of Thermocatalytic and Photo/Thermocatalytic Oxidation for VOCs Purification over Manganese-based Oxide Catalysts.

Volatile organic compounds (VOCs) are one of the main sources of air pollution, which are of wide concern because of their toxicity and serious threat to the environment and human health. Catalytic oxidation has been proven to be a promising and effective technology for VOCs abatement in the presence of heat or light. As environmentally friendly and low-cost materials, manganese-based oxides are the most competitive and promising candidates for the catalytic degradation of VOCs in thermocatalysis or photo/thermocatalysis.

Comprehensive analysis of prognostic immune-related genes in the tumor microenvironment of colorectal cancer.

In this study, we used the ESTIMATE algorithm to analyze clinical data and transcriptome profiles of 1635 colorectal cancer (CRC) samples from the Gene Expression Omnibus and The Cancer Genome Atlas databases and identify prognostic immune-related genes (IRGs). We identified 941 differentially expressed (4 downregulated and 937 upregulated) genes by comparing samples with high and low immune, stromal scores and tumor purity. LASSO Cox regression analyses showed that the risk score based on a ten-IRG signature was an independent prognostic factor in CRC.

Effect of Absorbed Sulfate Poisoning on the Performance of Catalytic Oxidation of VOCs over MnO.

Manganese oxides have displayed vast potential for future development in the field of catalytic abatement of volatile organic compounds (VOCs) because of their low cost, high stability, and enhanced catalytic activity. Manganese sulfate and manganese chloride are widely used as reaction sources to prepare manganese oxides. As reported, absorbed chloride usually affects the performance of catalysts.

The Construction and Comprehensive Prognostic Analysis of the LncRNA-Associated Competitive Endogenous RNAs Network in Colorectal Cancer.

Competing endogenous RNAs (ceRNAs) are a newly proposed RNA interaction mechanism that has been associated with the tumorigenesis, metastasis, diagnosis, and predicting survival of various cancers. In this study, we constructed a ceRNA network in colorectal cancer (CRC). Then, we sought to develop and validate a composite clinicopathologic-genomic nomogram using The Cancer Genome Atlas (TCGA) database.

hUC-MSCs ameliorated CUMS-induced depression by modulating complement C3 signaling-mediated microglial polarization during astrocyte-microglia crosstalk.

Background: Major depressive disorder (MDD) has been shown to be related to immune inflammation and the complement system. Previous studies have suggested that human umbilical cord mesenchymal stem cells (hUC-MSCs) play an important role in inflammatory diseases.

Methods: hUC-MSCs were administered into chronic unpredictable mild stress model (CUMS) mice through the tail vein once a week for 4 weeks.

Significant association between long non-coding RNA H19 polymorphisms and cancer susceptibility: A PRISMA-compliant meta-analysis and bioinformatics prediction.

Background: H19, a well-known long non-coding RNA, is involved in carcinogenesis and progression of multiple cancers. Molecular epidemiological research suggests that polymorphisms in H19 are associated with an increased risk of cancer, but the results are inconsistent. Thus, we performed a meta-analysis to estimate the associations between H19 polymorphisms and cancer susceptibility.

Weighted gene co-expression network analysis reveals specific modules and biomarkers in Parkinson's disease.

Background: Parkinson's disease (PD) ranks as the second most frequently occurring neurodegenerative disease. The precise pathogenic mechanism of this disease remains unknown. The aim of the present study was to identify the biomarkers in PD and classify the primary differentially expressed genes (DEGs).