Publications by authors named "Xiaojia Mu"

Arginine (Arg), as an important functional amino acids (AA), is essential for milk protein synthesis in lactating ruminants. Arg shares transporters with cationic and neutral AA in mammary epithelial cells. Therefore, competitive inhibition might exist among these AA in uptake by mammary epithelial cells.

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Glucose has been demonstrated to affect milk protein synthesis in dairy cows. However, its potential mechanisms has not been thoroughly studied. The objective of this study was to investigate the effects of glucose availability on αS1-casein synthesis, glucose uptake, metabolism, and the expression of proteins involved in AMP-activated protein kinase (AMPK)/mammalian target of rapamycin (mTOR) signaling pathway in bovine mammary epithelial cells (BMEC).

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Background: Currently, open reduction internal fixation is the conventional surgical method for treatment of double ulna and radius fracture. However, open reduction is associated with a high risk of complications. This case of forearm double fracture involved a patient treated using an Acumed intramedullary nail.

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Article Synopsis
  • Researchers have discovered that a fluorenylmethoxycarbonyl (Fmoc)-conjugated alanine-lactic acid (Ala-Lac) peptide sequence can self-assemble into water-gelling nanostructures without relying on traditional β-sheet hydrogen bonding.
  • Using various microscopic and spectroscopic techniques, they compared Fmoc-Ala-Lac with a standard self-assembling peptide, Fmoc-Ala-Ala, revealing distinct differences in size, shape, and mechanical properties, despite similarities at the angstrom scale.
  • Molecular dynamics simulations suggest that the structural differences between Fmoc-Ala-Lac and Fmoc-Ala-Ala affect their strength and hydrophilicity, influencing their higher-order assembly into nan
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We have investigated the self-assembly of fluorenylmethoxycarbonyl-conjugated dialanine (Fmoc-AA) molecules using combined computational and experimental approaches. Fmoc-AA gels were characterized using transmission electron microscopy (TEM), circular dichroism (CD), Fourier transform infrared (FTIR), and wide-angle X-ray scattering (WAXS). Computationally, we simulated the assembly of Fmoc-AA using molecular dynamics techniques.

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