A review on molecularly imprinted magnetic solid phase extraction emphasizing the analysis of antibiotics in complex matrices:Design, preparation, and application.

Magnetic solid phase extraction (MSPE) has been widely employed in the isolation and enrichment of antibiotics in complex matrices because it presents various unique advantages over traditional SPE including simple operation, fast extraction procedure, low cost and eco-friendliness. In recently years, magnetic molecularly imprinted nanoparticles (MMINs) containing highly specific recognition performance have been widely used to specific extraction of antibiotics under the format of MSPE. In this connection, recent advances of MMINs in the analysis of antibiotic residues are reviewed.

Facile and rapid preparation of fluorinated imprinted adsorbent for magnetic solid phase extraction of liquid-crystal monomers.

A new fluorinated imprinted adsorbent (MIA) for magnetic solid phase extraction (MSPE) of liquid crystal monomer (LCM) pollutants was one-pot prepared within 3.5 h using 4-[difluoro(3,4,5-trifluorophenoxy)methyl]-3,5-difluoro-4'-ethyl-biphenyl (DFBP) as template and 1H,1H,2H,2H-heptadecafluorodecyl acrylate/vinylanthracene as dual monomers. The structure, morphology, and magnetic properties of MIA fabricated were investigated by various characterization techniques.

Preparation of Purpurin-Fe Complex Natural Dye and Its Printing Performance on Silk Fabrics.

In order to shorten the process of textile printing with natural dyes, develop new methods, and improve the color fastness and quality of printed products, this study presents a novel approach by synthesizing a natural complex dye through the interaction between purpurin and Fe ions, resulting in a compound named purpurin-Fe (P-Fe). This synthesized complex dye was meticulously characterized using state-of-the-art analytical techniques, including Fourier transform infrared spectroscopy (FT-IR), ultraviolet-visible (UV-Vis) spectrophotometry, and scanning electron microscopy energy-dispersive spectroscopy (EDS). The characterization confirmed the successful complexation of purpurin with Fe ions.

The role of gut microbiome in mediating the effect of inflammatory bowel disease on hypertension: a two-step, two-sample Mendelian randomization study.

Objective: Investigating the causal connection that exists between inflammatory bowel disease (IBD) and hypertension (HT). To gain a deeper insight into the correlation among IBD, gut microbiota, and HT, we conducted a two-step, two-sample Mendelian randomization study.

Methods: An investigation of genome-wide association study (GWAS) summary-level data was utilized to conduct a two-sample Mendelian randomization (MR) analysis of genetically predicted inflammatory bowel disease: (12,882cases, 21,770controls) on Systolic/Diastolic blood pressure ( = 2,564).

Preparation of phenol-formaldehyde composite modified with chitosan for the simultaneous removal of antibiotics and heavy metal ions in waters.

In current study, a new adsorbent based on aminated phenol-formaldehyde composite was prepared using chitosan as modifier. Various techniques were adopted to characterize the morphology and structure of the prepared adsorbent. Due to the abundant amino groups, the obtained adsorbent presented satisfactory adsorption performance towards fluoroquinolones (FQs) and heavy metal ions (including Cu, Cd and Pb) by means of multiple forces including electrostatic, H-bonding, π-π stacking interactions (for FQs) and chelating force (for heavy metal ions).

Crystal structure and function of a phosphate starvation responsive protein phosphatase, GmHAD1-2 regulating soybean root development and flavonoid metabolism.

Phosphate (Pi) availability is well known to regulate plant root growth. However, it remains largely unknown how flavonoid synthesis participates in affecting plant root growth in response to Pi starvation. In the study, the crystal structure of a plant protein phosphatase, GmHAD1-2, was dissected using X-ray crystallography for the first time.

Hydrogen storage in a sandwich structure by assembly of BNs and MOFs.

Hybrid NUS-8/BNs with a sandwich-like structure were synthesized by layered h-BNs and MOF-NUS-8 assembly. Thanks to the more abundant exposed binding sites and partial ionic bonding properties of BN, the NUS-8/BN exhibits greatly improved H adsorption capacity, which is 1.7 times that of h-BN nanosheets.

On-site extraction of phenoxycarboxylic acid herbicides in environmental waters utilizing monolith-based in-tip microextraction technique.

On-site extraction plays a significant role in the reliable quantification of strong polar phenoxycarboxylic acid herbicides (PCAs) in aqueous samples. In current study, a new technique for the field sample preparation of PCAs was developed by means of three channels in-tip microextraction device (TCIM). To capture PCAs effectively, an extraction phase based on monolith (EPM) using vinylimidazole and divinylbenzene/ethylene dimethacrylate as monomer and cross-linkers, respectively, was in-situ synthesized in pipette tips.

One-pot fabrication of task specific magnetic adsorbent for the efficient isolation and capture of liquid-crystal monomers pollutants in waters prior to chromatographic quantification.

Background: Liquid crystal monomers (LCMs) have been classified as emerging organic pollutants. Efficient isolation and extraction is a critical step in the determination, and then knowing the occurrence and distribution of LCMs in environmental waters. However, the reported sample preparation techniques still suffer some dilemmas such as using large amount of organic solvent, low extraction capacity, tedious operation procedure and employment of expensive extraction column.

Comparison of the Efficacy Between Standard Measurement-Base Care (MBC) and Enhanced MBC for Major Depressive Disorder: A Pilot Study.

Purpose: To validate the efficacy of enhanced measurement-based care against standard measurement-based care in patients with major depressive disorder.

Patients And Methods: In this pilot study of an ongoing multicenter cluster randomized controlled trails, 160 patients diagnosed with major depressive disorder were enrolled from 2 mental health centers, with a plan to include 12 centers in total. One hundred patients engaged in a six-month evaluation using a technology-enhanced measurement-based care tool, including assessments of clinical symptoms, side effects, and functionality at baseline, two months, four months and six months.

Single-cell RNA sequencing reveals that NRF2 regulates vascular smooth muscle cell phenotypic switching in abdominal aortic aneurysm.

Abdominal aortic aneurysm (AAA) is a life-threatening disease characterized by extensive membrane destruction in the vascular wall that is closely associated with vascular smooth muscle cell (VSMC) phenotypic switching. A thorough understanding of the changes in regulatory factors during VSMC phenotypic switching is essential for managing AAA therapy. In this study, we revealed the impact of NRF2 on the modulation of VSMC phenotype and the development of AAA based on single-cell RNA sequencing analysis.

One-pot preparation of magnetic composite containing boronic acid groups and aminated multwalled carbon nanotubes for the speciation of Se(IV) and Se(VI) in water and milk samples by combination with chromatographic quantification.

Speciation of Se(IV) and Se(VI) is essential due to their significant differences in reactivity, toxicity and bioavailability. Efficient extraction is the pivotal step in the quantification of inorganic selenium species. In this work, a new magnetic nano-composite (MNC) containing boronic acid group and aminated multwalled carbon nanotubes was facilely fabricated by means of one-pot hydrothermal strategy.

Carbon emissions of power transmission and transformation projects in the whole life cycle for smart sustainable energy systems.

The study investigates the optimization of life cycle carbon emissions in smart sustainable energy systems through power transformation and transmission project power load predictions. Firstly, a multi-task learning-based short-term user load forecasting technique is developed, where the power load curves of multiple residential customers are grouped and classified using the K-means clustering method. Additionally, the Bidirectional Long Short-Term Memory (BiLSTM) technique is introduced to anticipate the power load intelligently.

Remediation of crude oil contaminated soil through an integrated biological-chemical-biological strategy.

A plausible approach to remediating petroleum contaminated soil is the integration of chemical and biological treatments. Using appropriate chemical oxidation, the integrated remediation can be effectively achieved to stimulate the biodegradation process, consequently bolstering the overall remediation effect. In this study, an integrated biological-chemical-biological strategy was proposed.

Circular RNAs in breast cancer diagnosis, treatment and prognosis.

Breast cancer has surpassed lung cancer to become the most common malignancy worldwide. The incidence rate and mortality rate of breast cancer continue to rise, which leads to a great burden on public health. Circular RNAs (circRNAs), a new class of noncoding RNAs (ncRNAs), have been recognized as important oncogenes or suppressors in regulating cancer initiation and progression.

Transcriptome analysis reveals therapeutic potential of NAMPT in protecting against abdominal aortic aneurysm in human and mouse.

Abdominal Aortic Aneurysm (AAA) is a life-threatening vascular disease characterized by the weakening and ballooning of the abdominal aorta, which has no effective therapeutic approaches due to unclear molecular mechanisms. Using single-cell RNA sequencing, we analyzed the molecular profile of individual cells within control and AAA abdominal aortas. We found cellular heterogeneity, with increased plasmacytoid dendritic cells and reduced endothelial cells and vascular smooth muscle cells (VSMCs) in AAA.

Fabrication and evaluation of a molecular-imprinted-polymer functionalized electrode for selective electric field-assisted solid-phase microextraction of phytohormones.

Specific extraction and separation plays a pivotal role in the accurate quantification of trace phytohormones (PHs). However, due to their high polarity, specific capture of PHs is challenging. In this study, under the assistance of electric field, a molecular-imprinted-polymer functionalized electrode (MIP@ED) was in-situ prepared using 3-indoleacetic acid (IAA) as template and employed as the adsorbent of electric field-assisted solid-phase microextraction (EA-SPME) for specific capture of PHs.

Task specific microextraction column based on monolith for magnetic field-assisted in-tube solid phase microextraction of vanadium species in complex samples prior to online chromatographic analysis.

The dominant species of vanadium (V) are V(IV) and V(V) which exhibit different toxicity and biological effects. Thus, speciation of V(IV) and V(V) is highly essential. Efficient sample preparation is the core step in the quantification of V(IV) and V(V).

AURKAIP1 actuates tumor progression through stabilizing DDX5 in triple negative breast cancer.

Aurora-A kinase interacting protein 1 (AURKAIP1) has been proved to take an intermediary role in cancer by functioning as a negative regulator of Aurora-A kinase. However, it remains unclear whether and how AURKAIP1 itself would directly engage in regulating malignancies. The expression levels of AURKAIP1 were detected in triple negative breast cancer (TNBC) by immunohistochemistry and western blots.

Long-term trend of future Cancer onset: A model-based prediction of Cancer incidence and onset age by region and gender.

Objectives: This study provided estimates of cancer incidence rate and onset age by Socio-demographic Index (SDI) regions and gender from 2020 to 2040, aiming to clarify the long-term patterns of future cancer onset.

Method: Based on the incidence data from the Global Burden of Diseases (GBD) 2019 study, we constructed the Bayesian age-period-cohort model to calculate the age-standardized incidence rates (ASIR) of cancers from 2020 to 2040. Using the average annual percentage change (AAPC) to quantify the trends of ASIR and the onset age.

Periostin drives extracellular matrix degradation, stemness, and chemoresistance by activating the MAPK/ERK signaling pathway in triple-negative breast cancer cells.

Background: Adipose tissue, which is mainly composed of adipocytes, is a crucial component of the tumor microenvironment, particularly in breast cancer. Adipocytes surround breast cancer cells and may participate in cell‒cell interactions in the breast microenvironment. However, little is currently known about how adipocytes influence the biological behavior of the surrounding breast cancer cells.

One-pot preparation of magnetic molecularly imprinted adsorbent with dual template molecules for simultaneously specific capture of sulfonamides and quinolones in water and milk samples.

Specific capture is a beneficial tactic in simultaneous monitoring of sulfonamides (SAs) and quinolones (QLs). For this purpose, a new magnetic molecularly imprinted adsorbent based on double-template molecules (DT-MIP@MNA) was facilely prepared by "one-pot" hydrothermal technique and utilized as the adsorbent of magnetic solid-phase extraction (MSPE). Molecular simulation technique was employed to quickly screen functional monomer.

FOXQ1 inhibits breast cancer ferroptosis and progression via the circ_0000643/miR-153/SLC7A11 axis.

Dysregulation of ferroptosis is involved in breast cancer progression and therapeutic responses. Inducing ferroptosis can be a potential therapeutic strategy for breast cancer treatment. Forkhead box Q1 (FOXQ1) is an oncogenic transcription factor that highly expressed and related with poor outcomes in various tumors.

Endothelial FoxM1 reactivates aging-impaired endothelial regeneration for vascular repair and resolution of inflammatory lung injury.

Aging is a major risk factor of high incidence and increased mortality of acute respiratory distress syndrome (ARDS). Here, we demonstrated that persistent lung injury and high mortality in aged mice after sepsis challenge were attributable to impaired endothelial regeneration and vascular repair. Genetic lineage tracing study showed that endothelial regeneration after sepsis-induced vascular injury was mediated by lung resident endothelial proliferation in young adult mice, whereas this intrinsic regenerative program was impaired in aged mice.