Axial Tensile Adhesively Bonded Performance of Carbon Fiber Composite Tubes Under Room-Temperature and Low-Temperature Circulation.

This study investigated the axial tensile performance of adhesively bonded T700/C204 carbon fiber composite and TC4 titanium alloy tubular single-lap joints under three distinct temperature conditions: room temperature, low temperature (-65 °C), and room-low-room-temperature cycling. Two configurations of adhesively bonded joints-composite-composite and composite-titanium-were tested. Specimens were designed to evaluate the influence of spew-fillet and perfect lap configurations on uniaxial tensile bonding strength across varying temperature environments.

ParSite is a multicolor DNA labeling system that allows for simultaneous imaging of triple genomic loci in living cells.

The organization of the human genome in space and time is critical for transcriptional regulation and cell fate determination. However, robust methods for tracking genome organization or genomic interactions over time in living cells are lacking. Here, we developed a multicolor DNA labeling system, ParSite, to simultaneously track triple genomic loci in the U2OS cells.

Efficacy, safety, and multi-omics analysis of pembrolizumab combined with nab-paclitaxel and platinum as first-line treatment in patients with recurrent or metastatic head and neck squamous cell carcinoma: A single-arm phase 2 study.

Objective: Based on the findings of the KEYNOTE-048 study, pembrolizumab in combination with platinum and fluorouracil is the standard first-line treatment for recurrent or metastatic head and neck squamous cell carcinoma (R/M HNSCC). The efficacy and safety of pembrolizumab combined with nab-paclitaxel and platinum in such patients remain unexplored.

Methods: This single-arm phase 2 study enrolled patients with R/M HNSCC who received pembrolizumab (200 mg), nab-paclitaxel (260 mg/m²), and either cisplatin (75 mg/m²) or carboplatin [area under the curve (AUC) 5] every 21 d for up to six cycles, followed by pembrolizumab maintenance therapy.

Diamine Crosslinked Addition-Type Diblock Poly(Norbornene)s-Based Anion Exchange Membranes with High Conductivity and Stability for Fuel Cell Applications.

Anion exchange membranes (AEMs) as a kind of important functional material are widely used in fuel cells. However, synthetic AEMs generally suffer from low conductivity, poor alkaline stability, and poor dimensional stability. Constructing efficient ion transport channels is widely regarded as one of the most effective strategies for developing AEMs with high conductivity and low swelling ratio.

The Comparative Oncology of Canine Malignant Melanoma in Targeted Therapy: A Systematic Review of Experiments and Animal Model Reports.

Canine malignant melanoma (CMM) is highly aggressive and mostly located in the oral cavity. CMM is the predominant type of canine oral malignancy and shows striking homologies with human mucosal melanoma. In comparative oncology, canine oral melanomas (COMs), as spontaneous tumor models, have the potential to acquire a unique value as a translational model of rare human melanoma subtypes.

Recent advances in tailoring the microenvironment of Pd-based catalysts for enhancing the performance in the direct synthesis of hydrogen peroxide.

Hydrogen peroxide (HO) is a valuable clean chemical, which is widely applied in modern industrial production. In the past few decades, HO has been mainly produced industrially by the anthraquinone method, but the process is complicated and energy consuming, which is only economical for large-scale production and is harmful to the environment. The direct synthesis of HO is considered a promising process to replace the anthraquinone method with high atomic economy, no hazardous by-products, and convenient operation, which has attracted much attention.

Genome-Wide Analysis of Aquaporins Gene Family in and Its Expression Patterns in Response to Drought, Salt Stress, and Phytohormones.

Aquaporins (AQPs) play an essential role in membrane water transport during plant responses to water stresses centered on conventional upstream signals. Phytohormones (PHs) regulate plant growth and yield, working with transcription factors to help plants withstand environmental challenges and regulate physiological and chemical processes. The AQP gene family is important, so researchers have studied its function and regulatory system in numerous species.

Comparative Study of PtM (M=Cu, Zn, Ga, Mn, Fe, In, Ce) Bimetals on Zincosilicate for Propane Dehydrogenation Reaction.

Silicoaluminate zeolites have relatively strong Brönsted (B) acid properties that can easily lead to deep cracking reactions, making them less favourable as carriers for propane dehydrogenation. Here, we utilise zincosilicate zeolite with less B-acid produced by the introduction of the heteroatom Zn into the framework as a carrier, followed by simultaneous ion exchange (IE) of M monometallic or PtM bimetallic (M=Cu, Zn and Ga, etc.).

Construction of bismuth based MOF for efficient removal of sodium diclofenac via adsorption and photocatalysis.

The mass production and widespread use of Pharmaceuticals and Personal Care Products (PPCPs) have posed a serious threat to the water environment and public health. In this work, a green metal-based Metal Organic Framework (MOF) Bi-NH-BDC was prepared and characterized, and the adsorption characteristics of Bi-NH-BDC were investigated with typical PPCPs-diclofenac sodium (DCF). It was found that DCF mainly covered the adsorbent surface as a single molecular layer, the adsorption reaction was a spontaneous, entropy-increasing exothermic process and the adsorption mechanisms between Bi-NH-BDC and DCF were hydrogen bonding, π-π interactions and electrostatic interactions.

Waste Plastic-Supported Pd Single-Atom Catalyst for Hydrogenation.

As worldwide plastic pollution continues to rise, innovative ideas for effective reuse and recycling of waste plastic are needed. Single-atom catalysts (SACs), which are known for their high activity and selectivity, present unique advantages in facilitating plastic degradation and conversion. Waste plastic can be used as a support or raw material to create SACs, which reduces waste generation while simultaneously utilizing waste as a resource.

Bibliometric analysis of research in epilepsy and comorbid depression from 2014 to 2023.

Background: Epilepsy and depression have complicated bidirectional relationships. Our study aimed to explore the field of epilepsy comorbid with depression in a bibliometric perspective from 2014-2023.

Aim: To improve our understanding of epilepsy and depression by evaluating the relationship between epilepsy and depression, bibliometric analyses were performed.

Facet-dependent synthesis of HO from H and O over single Pt atom-modified Pd nanocrystal catalysts.

Hydrogen peroxide (HO) is one of the most valuable clean energy sources with a rapidly growing requirement in industry and daily life. The direct synthesis of HO from hydrogen and oxygen is considered to be an economical and environmentally friendly manufacturing route to replace the traditional anthraquinone method, although it remains a formidable challenge owing to low HO selectivity and production. Here, we report a catalyst consisting of Pd(111) nanocrystals on TiO modified with single Pt atoms (PtPd(111)/TiO), which displays outstanding reactivity, producing 1921.

Changes of soil carbon along precipitation gradients in three typical vegetation types in the Alxa desert region, China.

The changes and influencing factors of soil inorganic carbon (SIC) and organic carbon (SOC) on precipitation gradients are crucial for predicting and evaluating carbon storage changes at the regional scale. However, people's understanding of the distribution characteristics of SOC and SIC reserves on regional precipitation gradients is insufficient, and the main environmental variables that affect SOC and SIC changes are also not well understood. Therefore, this study focuses on the Alxa region and selects five regions covered by three typical desert vegetation types, Zygophyllum xanthoxylon (ZX), Nitraria tangutorum (NT), and Reaumuria songarica (RS), along the climate transect where precipitation gradually increases.

The dominant influencing factors of desertification and ecological risk changes in Qinghai Area of Qilian Mountains National Park: Climate change or human activity?

Transitional features of desert environments partially determine the risks associated with ecosystems. Influenced by climate change and human activities, the variability and uncertainty of desertification levels and ecological risks in the Qinghai Area of Qilian Mountain National Park (QMNPQA) has become increasingly prominent. As a critical ecological barrier in northwest China, monitoring desertification dynamics and ecological risks is crucial for maintaining ecosystem stability.

Deciphering the Prognostic Significance of MYD88 and CD79B Mutations in Diffuse Large B-Cell Lymphoma: Insights into Treatment Outcomes.

Background: The clinical and genetic characteristics, as well as treatment outcomes, of diffuse large B-cell lymphoma (DLBCL) patients with different MYD88 and CD79B mutation status merit further investigation.

Objective: This study aims to investigate the distinctions in clinical manifestations, genetic characteristics, and treatment outcomes among MYD88-CD79B, MYD88/CD79B, and MYD88-CD79B DLBCL patients.

Patients And Methods: Clinical and genetic characteristics, along with treatment outcomes among 2696 DLBCL patients bearing MYD88-CD79B, MYD88/CD79B, and MYD88-CD79B treated with R-CHOP/R-CHOP-like regimens from the Cancer Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College and six external cohorts were analyzed.

Genomic diversity of the pathogenic fungus Aspergillus fumigatus in Japan reveals the complex genomic basis of azole resistance.

Aspergillus fumigatus is a pathogenic fungus with a global distribution. The emergence of azole-resistant A. fumigatus (ARAf) other than the TR-mutants is a problem in Japan.

Construction of SU-102 for adsorption and photocatalytic synergistic removal of tetracycline.

Tetracycline (TC) is a significant group of broad-spectrum antibiotics that are frequently employed in medical health and animal husbandry. However, the problem of TC residues has been increasing globally with the large-scale production and widespread use, posing a serious threat to the human health and ecological environment. In this paper, a green plant-based MOF SU-102 was prepared, and the adsorption characteristics of SU-102 on TC were investigated.

Tracking pairwise genomic loci by the ParB-ParS and Noc-NBS systems in living cells.

The dynamics of genomic loci pairs and their interactions are essential for transcriptional regulation and genome organization. However, a robust method for tracking pairwise genomic loci in living cells is lacking. Here we developed a multicolor DNA labeling system, mParSpot (multicolor ParSpot), to track pairs of genomic loci and their interactions in living cells.

Adsorption Behavior of Dissolved Gas Molecules in Transformer Oil on Rh Modified GeSe Monolayer.

Dissolved gas analysis in transformer oil is useful for detecting early transformer failures. The research on gas sensors for monitoring dissolved gas in transformer oil has attracted wide attention from academia and industry. In this study, Rh-doped GeSe monolayers were used as gas sensing materials based on the density functional theory (DFT).

Multi-Scale Attention Network for Building Extraction from High-Resolution Remote Sensing Images.

The precise building extraction from high-resolution remote sensing images holds significant application for urban planning, resource management, and environmental conservation. In recent years, deep neural networks (DNNs) have garnered substantial attention for their adeptness in learning and extracting features, becoming integral to building extraction methodologies and yielding noteworthy performance outcomes. Nonetheless, prevailing DNN-based models for building extraction often overlook spatial information during the feature extraction phase.

Effects of long-term afforestation on soil water and carbon in the Alxa Plateau.

Plantations in dry and semi-arid areas significantly affect the soil's ability to store carbon and maintain a stable water balance. It is yet unclear, though, how planted trees in these regions might impact the soil's carbon and water levels. As a forest ages, it is unknown how soil water and soil carbon interact with one another.

Antennal excision reveals disparate olfactory expression patterns within castes in Reticulitermes aculabialis (Isoptera: Rhinotermitidae).

In lower termites, which exhibit a high degree of compound eye degradation or absence, antennae play a pivotal role in information acquisition. This comprehensive study investigates the olfactory system of Reticulitermes aculabialis, spanning five developmental stages and three castes. Initially, we characterize the structures and distribution of antennal sensilla across different developmental stages.

The Euphrates Poplar Responses to Abiotic Stress and Its Unique Traits in Dry Regions of China (Xinjiang and Inner Mongolia): What Should We Know?

At the moment, drought, salinity, and low-temperature stress are ubiquitous environmental issues. In arid regions including Xinjiang and Inner Mongolia and other areas worldwide, the area of tree plantations appears to be rising, triggering tree growth. Water is a vital resource in the agricultural systems of countries impacted by aridity and salinity.

Boosting the Catalase-Like Activity of SAzymes via Facile Tuning of the Distances between Neighboring Atoms in Single-Iron Sites.

A nanozyme with neighboring single-iron sites (Fe -SAzyme) was introduced as a bioinspired catalase mimic, featuring excellent activity under varied conditions, twice as high as that of random Fe -SAzyme and ultrahigh H O affinity as that of bioenzymes. Surprisingly, the interatomic spacing tuning between adjacent iron sites also suppressed the competitive peroxidase pathway, remarkably increasing the catalase/peroxidase selectivity up to ~6 times compared to Fe -SAzyme. This dramatically switched the catalytic activity of Fe-SAzymes from generating (i.