Association between serum uric acid levels and arterial stiffness in patients with psoriasis.

This study examined the association between serum uric acid levels (SUA) and arterial stiffness in patients with psoriasis vulgaris. A cross-sectional study was conducted on 205 consecutive patients with psoriasis vulgaris who visited the Dermatology Clinic of China-Japan Friendship Hospital between March 2022 and July 2024. Arterial stiffness was assessed by measuring brachial-ankle pulse wave velocity (baPWV).

Downregulation of PTEN expression in psoriatic lesions.

Background: Considerable studies showed that tumor suppressor phosphatase and tensin homolog (PTEN) deleted on chromosome 10 is a major tumor suppressor, which inhibits cell proliferation through inactivation of the PI3 kinase (PI3K)/Akt signal pathway. In many human tumors, there is loss of function or mutations in PTEN. In our previous study, it was found that Akt activity in psoriatic lesions increased compared with that in normal controls.

Effect of new Pulian Ointment () in treating psoriasis of blood-heat syndrome: A randomized controlled trial.

Objective: To objectively assess the clinical efficacy and safety of a new Pulian Ointment (, NPLO) in treating psoriasis of blood-heat syndrome of Chinese medicine.

Methods: A total of 108 patients with psoriasis of blood-heat syndrome were equally assigned, using a randomizing digital table, to the test group treated externally with NPLO and the control group treated with placebo; the medication was done using a singleblinded method twice a day. Meanwhile, all patients received by oral intake a conventional Chinese decoction for clearing heat and cooling blood; the therapeutic course was 4 weeks for both groups.

Comparison between immunofluorescence and PCR in detecting human papilloma virus in condyloma acuminata.

Objective: To compare the effectiveness of immunofluorescence and polymerase chain reaction (PCR) in detecting human papilloma virus (HPV) in condyloma acuminata (CA).

Methods: HPVs in CA tissues from 60 patients were detected by immunofluorescence and PCR, respectively. Different subtypes of HPVs were also identified with restriction fragment length polymorphism (RFLP).

[Detecting HPV DNA in tissues of external genital squamous cell carcinoma in situ by PCR-RFLP technique].

Objective: To study the relationship between the infection of human papillomavirus (HPV) and external genital squamous cell carcinoma in situ.

Methods: HPV DNA was detected with the consensus primer by polymerase chain reaction (PCR) and its type was determined by restriction fragment length polymorphism (RFLP).

Results: HPV DNA was detected and HPV16 was the most frequently identified type in 29 (56.