Publications by authors named "Xiaohang Guo"

Brain tumor diagnosis is an important task in prognosing and treatment planning of the patients with brain cancer. in the meantime, using the Magnetic Resonance Imaging (MRI) as a commonly used non-invasive imaging technique provide the experts a helpful view for detecting the brain tumors. While deep learning methods have shown significant success in analyzing medical images, they often require careful design of architecture and tuning of hyperparameters to achieve optimal results.

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Article Synopsis
  • Self-assembly of hydrogels is being researched as a treatment for traumatic brain injury (TBI) but traditional methods face issues with safety and clinical application due to reliance on high molecular carriers and inactive substances.
  • A novel small molecule hydrogel (GBR-gel) uses compounds from Chinese medicines to deliver drugs without the need for additional inactive components, making it easier and cheaper to produce.
  • GBR-gel shows promise in quickly addressing TBI by improving synapse function and reducing inflammation, offering a new potential treatment strategy for brain injuries.
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Article Synopsis
  • Novel biomaterials derived from natural herbal products are gaining importance in treating diseases but face challenges in preparation and complexity.
  • Recent advancements in self-assembly techniques are yielding bioactive supramolecular materials, such as gels and nanoparticles, that are easier to produce and multifunctional.
  • The review covers the development, benefits, and limitations of these materials, analyzes their self-assembly strategies, and discusses their biomedical applications and future research opportunities.
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Cognitive ability, as an early human capital, has always been an important research object in modern education and labor economics. Despite growing awareness of the importance of height in individual growth and development, there are few empirical studies on height and cognitive ability. Using the data from the China Education Panel Survey, this paper examined the impact of height on the cognitive ability of adolescents and explored the reasons behind the Chinese pursuit of height growth and the potential impact mechanism.

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Background: Xuefu Zhuyu decoction (XFZYD) is a traditional Chinese herbal formula known for its ability to eliminate blood stasis and improve blood circulation, providing neuroprotection against severe traumatic brain injury (sTBI). However, the underlying mechanism is still unclear.

Purpose: We aim to investigate the neuroprotective effects of XFZYD in sTBI from a novel mechanistic perspective of miRNA-mRNA.

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Ethnopharmacological Relevance: The repairment of myelin sheaths is crucial for mitigating neurological impairments of intracerebral hemorrhage (ICH). However, the current research on remyelination processes in ICH remains limited. A representative traditional Chinese medicine, Buyang Huanwu decoction (BYHWD), shows a promising therapeutic strategy for ICH treatment.

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In the last decades, titania (or TiO) particles played a crucial role in the development of photo-catalysis and better environmentally-friendly energy-harvesting techniques. In this work, we engineer a new generation of TiO particles rich in oxygen vacancies using a modified sol-gel synthesis. By design, these vacancy-rich particles efficiently absorb visible light to allow carefully-controlled light-induced conversion to the anatase or rutile crystalline phases.

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is the underlying cause of a significant number of outbreaks of gastrointestinal illness in humans and animals worldwide. The purpose of this study was to elucidate the prevalence and genetic diversity of in captive alpine musk deer () in China. A total of 202 fecal samples were collected from three farms in Gansu Province, China.

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Background: Coronavirus disease 2019 (COVID-19) keeps spreading globally. Chinese medicine (CM) exerts a critical role for the prevention or therapy of COVID-19 in an integrative and holistic way. However, mining and development of early, efficient, multisite binding CMs that inhibit the cytokine storm are imminent.

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Background: Severe traumatic brain injury (TBI) has become a global health problem and causes a vast worldwide societal burden. However, distinct mechanisms between acute and subacute stages have not been systemically revealed. The present study aimed to identify differentially expressed proteins in severe TBI from the acute to subacute phase.

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Since the number of raw material selections for the synthesis of carbon dots (CDs) has grown extensively, herbal medicine as a precursor receives an increasing amount of attention. Compared with other biomass precursors, CDs derived from herbal medicine (HM-CDs) have become the most recent incomer in the family of CDs. In recent ten years, a great many studies have revealed that HM-CDs tend to be good at theranostics without drug loading.

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This paper proposes a new paradigm in polymer light-emitting diode (PLED) fabrication by using a uniform electrosprayed microparticle film as the active layer. Among the seven electrospraying parameters analyzed, three crucial parameters are statistically identified and optimized to obtain thin electrosprayed microparticle layers. Using optimized electrospraying conditions, single-color red-emitting PLED (MEH-PPV) with a peak current density of 16.

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We report significantly improved silicon nanowire/TiO n-n heterojunction solar cells prepared by sol-gel synthesis of TiO thin film atop vertically aligned silicon nanowire arrays obtained by facile metal-assisted wet electroless chemical etching of a bulk highly doped n-type silicon wafer. As we show here, chemical treatment of the nanowire arrays prior to depositing the sol-gel precursor has dramatic consequences on the device performance. While hydrofluoric treatment to remove the native oxide already improves significantly the device performances, hydrobromic (HBr) treatment consistently yields by far the best device performances with power conversion efficiencies ranging between 4.

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The Kank1 gene is one of the important members of the Kank gene family. As an important adaptor protein, Kank1 plays a significant role in the genesis and development of many malignant tumors. It was recently discovered that the Kank1 gene is a new cancer suppressor, and its expression is significantly downregulated or it is not expressed in kidney cancer, bladder cancer, prostate cancer, lung cancer and breast cancer.

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