Publications by authors named "Xiaoguang Hou"
Eliminating the second CT scan of dual-tracer total-body PET/CT via deep learning-based image synthesis and registration.
Eur J Nucl Med Mol Imaging
February 2025
Purpose: This study aims to develop and validate a deep learning framework designed to eliminate the second CT scan of dual-tracer total-body PET/CT imaging.
Methods: We retrospectively included three cohorts of 247 patients who underwent dual-tracer total-body PET/CT imaging on two separate days (time interval:1-11 days). Out of these, 167 underwent [Ga]Ga-DOTATATE/[F]FDG, 50 underwent [Ga]Ga-PSMA-11/[F]FDG, and 30 underwent [Ga]Ga-FAPI-04/[F]FDG.
Article Synopsis
- This study investigates the feasibility of using a low-dose PET/CT scan protocol (1/3 of the standard dose) for cancer patients, focusing on its effectiveness relative to the full-dose regimen.
- Seventy-four cancer patients participated, with assessments showing that image quality and lesion detection rates for the low-dose group were comparable to those found in the full-dose group, particularly when stratified by body mass index (BMI).
- The findings suggest that the BMI-stratified 1/3-dose approach is a viable option, maintaining diagnostic accuracy while potentially enhancing the personalization of clinical imaging protocols.
Article Synopsis
- The study aimed to find a reliable standardized uptake value (SUV) for using in clinical settings by comparing various normalization methods for the SUV of Tc-MDP in normal spine and pelvis bones using SPECT/CT scans. !* -
- Researchers analyzed data from 500 oncology patients, calculating average SUVs based on different body metrics and finding that the SUV method had the least variability, suggesting it might be the most consistent option for clinical use. !* -
- The findings indicate that the SUV from Tc-MDP could be a useful reference for assessing tumor bone metastasis, but results should be evaluated site-specifically, with SUV showing the highest robustness compared to other normalization methods. !*
Purpose: To investigate the feasibility of reducing the acquisition time for continuous dynamic positron emission tomography (PET) while retaining acceptable performance in quantifying kinetic metrics of 2-[F]-fluoro-2-deoxy-D-glucose ([F]FDG) in tumors.
Methods: In total, 78 oncological patients underwent total-body dynamic PET imaging for ≥ 60 min, with 8, 20, and 50 patients receiving full activity (3.7 MBq/kg), half activity (1.
Gastric Schwannoma is a rare benign mesenchymal tumor that accounts for only 0.2% of all gastric tumors. The current study presents a case of gastric Schwannoma misdiagnosed as malignant gastrointestinal stromal tumor (GIST) by esophagogastroduodenoscopy, endoscopic ultrasonography, and contrast-enhanced or not enhanced and (18)F-FDG PET/CT imaging.
View Article and Find Full Text PDFGram-negative bacterium Escherichia coli and the Gram-positive Deinococcus radiodurans fundamentally differ in their cell structures and gene regulations. We have previously reported that IrrE, a Deinococcus genus-specific global regulator, confers significantly enhanced tolerance to various abiotic stresses. To better understand the global effects of IrrE on the regulatory networks, we carried out combined transcriptome and proteome analysis of E.
View Article and Find Full Text PDFBackground: Globally, about 20% of cultivated land is now affected by salinity. Salt tolerance is a trait of importance to all crops in saline soils. Previous efforts to improve salt tolerance in crop plants have met with only limited success.
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