Synopsis of recent research by authors named "Xiaofu Yu"
- Xiaofu Yu's research focuses on the intersection of cancer treatment modalities, notably exploring combinations of immune checkpoint inhibitors with chemotherapy for various cancer types, including HER2-negative advanced gastric cancer and non-small cell lung cancer.
- Recent studies indicate that the combination therapies may enhance tumor immune responses and potentially improve treatment efficacy, as seen in findings related to triple-negative breast cancer's radioresistance and the role of MPZL1 in lung adenocarcinoma progression.
- Additionally, Yu's work has identified key molecular mechanisms and targets for therapeutic intervention in cancers, including the KLF9-epithelial-mesenchymal transition feedback loop in hepatocellular carcinoma and the suppression of the IGF-2-IGF1R-AKT signaling cascade by WISP3 in esophageal squamous cell carcinoma.