Synopsis of recent research by authors named "Xiaofu Jin"
- Xiaofu Jin's recent research focuses on enhancing immune responses against leukemia, particularly exploring the efficacy of immunoconjugates like the muramyl dipeptide conjugated to anti-CD10 monoclonal antibodies to combat acute leukemia in animal models.
- In a notable 2023 study, Jin demonstrated that these immunoconjugates could significantly inhibit acute leukemia in nude mice, thereby providing insights into potential therapeutic strategies that target minimal residual disease (MRD) to prevent recurrence.
- In addition to therapeutic research, Jin also contributed to the establishment of a robust animal model for acute B lymphoblastic leukemia (B-ALL) with MRD, allowing for further investigation of leukemia characteristics and treatment responses in a controlled environment.