Efficacy of a basal insulin dose management smartphone application for controlling fasting blood glucose in patients with type-2 diabetes mellitus: A single-centre, randomised clinical study.

Objective: To explore the efficacy and safety of the 'Walk with you' application for titrating basal insulin (BI) doses in type-2 diabetes mellitus (T2DM) hospitalised patients.

Methods: This was a randomised, single-centre, open-label, controlled clinical trial to compare the changes in fasting blood glucose (FBG) and postprandial blood glucose (PBG), time to reach target FBG (FBG-TRT), incidence of hypoglycaemia events and FBG coefficient of variation in the application group (weight-based titration of BI dose regimen) and control group (typical adjustment regimen).

Patients: This study selected 173 patients with T2DM using basal-prandial insulin therapy who were admitted to Binhaiwan Central Hospital of Dongguan between December 2021 and December 2022.

Curly fish scales-like NiMoS electrodeposited on PEDOT-rGO with uneven surface as ultrafast response electrode for electrocatalytic glucose, nitrite and hydrogen peroxide.

The difficulty to achieve rapid detection is the limitation of many enzyme-free sensors today. Thus, designing tri-functionalsensors with ultra-fast and efficientdeterminationis a challenging taskin biological science. Herein, curly fish scales-like NiMoS active materials was anchored on poly (3,4-ethylenedioxythiophene)-reduced graphene oxide (PEDOT-rGO) hybrid membranes with uneven surface (NiMoS/PEDOT-rGO) as a high-performance tri-functional catalyst for glucose, nitrite and hydrogen peroxide determination.

Meta-analysis of the prognostic value of pretreatment serum ferritin in hepatobiliary and pancreas (HBP) cancers.

Background And Objectives: Studies have shown that serum ferritin (SF) has unfavourable prognostic value in hepatobiliary and pancreas (HBP) cancers. This meta-analysis aimed to comprehensively assess the prognostic role of pretreatment SF in patients with HBP cancers.

Methods: Eligible studies published before January 2020 were obtained through a comprehensive search in the PubMed, Web of Science, Cochrane Library and EMBASE databases.

Clinicopathological and prognostic value of preoperative lymphocyte to monocyte ratio for hepatocellular carcinoma following curative resection: A meta-analysis including 4,092 patients.

Background: Previous studies have reported that lymphocyte-to-monocyte ratio (LMR) had novel prognostic value in hepatocellular carcinoma (HCC). The purpose of this meta-analysis was to synthetically evaluate the prognostic role of preoperative LMR in HCC patients following curative resection.

Methods: Eligible studies were acquired through searching Pubmed, Web of Science, Cochrane Library and EMbase update to September 2019.

Nickel sulfide nanoworm network architecture as a binder-free high-performance non-enzymatic glucose sensor.

Nickel sulfide nanoworm (NiS NW) network architecture was directly grown on the poly (3,4-ethylenedioxythiophene)-reduced graphene oxide hybrid films (PEDOT-rGO HFs) modified on glassy carbon electrode (GCE), acting as a binder-free sensor for high-performance non-enzymatic glucose monitoring. The sensor exhibited the satisfactory sensitivity (2123 μA mM cm), wide linear range (15~9105 μM), low detection limit (0.48 μM), and rapid response time (< 1.

Circ_0091581 Promotes the Progression of Hepatocellular Carcinoma Through Targeting miR-591/FOSL2 Axis.

Background: Circular RNAs (circRNAs) have shown crucial regulatory roles in cancer biology. We aimed to uncover the role and underlying mechanism of circ_0091581 in hepatocellular carcinoma (HCC) progression.

Methods: The abundance of circ_0091581, microRNA-591 (miR-591) and FOS like 2, AP-1 transcription factor subunit (FOSL2) was measured by quantitative real-time polymerase chain reaction.