Metabolomic signature between diabetic and non-diabetic obese patients: A protocol for systematic review.

Background: Type 2 diabetes mellitus (T2DM) is a chronic and progressive condition defined by hyperglycemia caused by abnormalities in insulin production, insulin receptor sensitivity, or both. Several studies have revealed that higher body mass index (BMI) is associated with increasing risk of developing diabetes. In this study, we perform a protocol for systematic review to explore metabolite biomarkers that could be used to identify T2DM in obese subjects.

Visual analysis of obesity and hypothyroidism: A bibliometric analysis.

Background: The prevalence of obesity is gradually increasing and is closely associated with hypothyroidism. It is of research interest to explore the association between obesity and hypothyroidism and the current status of research.

Methods: We chose the Web of Science Core Collection (WoSCC) database as the data source and searched to obtain relevant literature on obesity and hypothyroidism.

Effectiveness and safety of different academic schools of traditional Chinese medicine in the treatment of obesity: A protocol for systematic review and meta-analysis.

Background: Obesity is a global epidemic. Since 1975, the global obesity rate has almost tripled. Although many systematic reviews and clinical trials have shown that traditional Chinese medicine (TCM) can effectively treat obesity, the effectiveness and safety of different academic schools of TCM in treating obesity have not been systematically evaluated.

Effectiveness and safety of acupuncture combined with hot compress in the treatment of obese adolescents with insulin resistance: A protocol for systematic review and meta-analysis.

Background: In recent years, the incidence of obesity patients has become younger and younger, and adolescents are gradually becoming one of the groups with a high incidence of obesity. Although several systematic reviews and clinical trials suggest that acupuncture and warm compresses may be effective in the treatment of obesity, the effectiveness and safety of acupuncture combined with warm compresses in the treatment of obesity insulin resistance (IR) in adolescents have not been systematically reviewed.

Methods: The search language of this study is Chinese and English, and the data of Medline, PubMed, Embase, Cochrane Web of Science, China Biomedical Literature Database, Central Controlled Trial Registration Center, and China Scientific Journal Database were searched for this study respectively, from the date of creation of the above data to December 2022.

Identification of hub genes and candidate herbal treatment in obesity through integrated bioinformatic analysis and reverse network pharmacology.

Obesity is a global epidemic elevating the risk of various metabolic disorders. As there is a lack of effective drugs to treat obesity, we combined bioinformatics and reverse network pharmacology in this study to identify effective herbs to treat obesity. We identified 1011 differentially expressed genes (DEGs) of adipose tissue after weight loss by analyzing five expression profiles (GSE103766, GSE35411, GSE112307, GSE43471, and GSE35710) from the Gene Expression Omnibus (GEO) database.

Efficacy and safety of acupuncture in the treatment of foot drop in post-stroke: A protocol for systematic review and meta-analysis.

Background: Foot drop is a common complication in post-stroke. Patients with foot drop are at high risk for falls and fall-related injuries. Accordingly, it can reduce independence and quality of life in patients.

Role of melatonin in respiratory diseases (Review).

Melatonin, primarily secreted by the pineal gland, is an anthracemal compound. Its chemical name is N-acetyl-5-methoxytryptamine. Great advances in melatonin-related research have been made, including the understanding of its roles in the rhythm of the sleep/wake cycle, retardation of aging processes, as well as antioxidant and/or anti-inflammatory effects.

Effect of electroacupuncture on glucose and lipid metabolism in type 2 diabetes: A protocol for systematic review and meta-analysis.

Background: Type 2 diabetes mellitus (T2DM) is a global pandemic with a significant negative impact on health-related quality of life. Worldwide, the prevalence of T2DM has almost doubled since 1980. Although multiple systematic reviews and clinical trials have suggested that electroacupuncture could be effective for T2DM treatment, whether it can improve glucose and lipid metabolism has not been systematically reviewed.