[Retracted] MicroRNA‑126 exerts antitumor functions in ovarian cancer by targeting EGFL7 and affecting epithelial‑to‑mesenchymal transition and ERK/MAPK signaling pathway.

[This retracts the article DOI: 10.3892/ol.2020.

Spatial-frequency-oriented measurement strategy in two-dimensional slope deflectometry systems.

A single-point-probe-based slope profiler is a common measurement scheme for the measurement of freeform optical surfaces, which has been a challenging research direction. Efficiency is a key issue in two-dimensional scanning-based measurement. This study establishes a measurement system simulation model and reveals that the height reconstruction accuracy of different reconstruction algorithms is primarily correlated with the sampling density.

Effect of an artificial intelligence-assisted system on endoscopic diagnosis of superficial oesophageal squamous cell carcinoma and precancerous lesions: a multicentre, tandem, double-blind, randomised controlled trial.

Background: Despite the usefulness of white light endoscopy (WLE) and non-magnified narrow-band imaging (NBI) for screening for superficial oesophageal squamous cell carcinoma and precancerous lesions, these lesions might be missed due to their subtle features and interpretation variations among endoscopists. Our team has developed an artificial intelligence (AI) system to detect superficial oesophageal squamous cell carcinoma and precancerous lesions using WLE and non-magnified NBI. We aimed to evaluate the auxiliary diagnostic performance of the AI system in a real clinical setting.

Impact of Submucosal Saline Injection During Cold Snare Polypectomy for Colorectal Polyps Sized 3-9 mm: A Multicenter Randomized Controlled Trial.

Introduction: The role of submucosal injection during cold snare polypectomy (CSP) remains uncertain. In this study, we investigated the impact of submucosal saline injection during CSP for colorectal polyps sized 3-9 mm.

Methods: This was a multicenter randomized controlled trial conducted in 6 Chinese centers between July and September 2020 (ChiCTR2000034423).

Danger-associate peptide regulates root immunity in Arabidopsis.

Plant elicitor peptides (Peps) are recognized by two receptor-like kinases, PEPR1 and PEPR2, and trigger plant immunity responses and root growth inhibition. In this study, we reveal that the Pep-PEPR system triggers root immunity responses in Arabidopsis. Pep1 incubation initiated callose and lignin deposition in roots of wild type but not in that of pepr1 pepr2 mutant seedlings.

The genome of provides a new insight into cold tolerance and the evolutionary position of magnoliids.

, a member of the Magnoliaceae of magnoliids, is one of the most economically valuable, phylogenetic and ornamental tree species in Eastern China. Here, the 1.64 Gb chromosome-level assembly covers 96.

De Novo Assembly of a Sarcocarp Transcriptome Set Identifies AaMYB1 as a Regulator of Anthocyanin Biosynthesis in var. purpurea.

The kiwifruit ( var. purpurea) produces oval shaped fruits containing a slightly green or mauve outer exocarp and a purple-flesh endocarp with rows of tiny black seeds. The flesh color of the fruit results from a range of anthocyanin compounds, and is an important trait for kiwifruit consumers.

Transcriptional Analysis on Resistant and Susceptible Kiwifruit Genotypes Activating Different Plant-Immunity Processes against pv. .

pv. (Psa), a bacterial pathogen, is a severe threat to kiwifruit production. To elucidate the species-specific interaction between Psa and kiwifruit, transcriptomic-profiles analyses were conducted, under Psa-infected treatment and mock-inoculated control, on shoots of resistant Maohua (MH) and susceptible Hongyang (HY) kiwifruit varieties.

Profiles of antibiotic- and heavy metal-related resistance genes in animal manure revealed using a metagenomic analysis.

Farmed animals produce excrement containing excessive amounts of toxic heavy metals as a result of consuming compound feed as well as receiving medical treatments, and the presence of these heavy metals may aggravate the risk of spreading drug-resistance genes through co-selection during manure treatment and application processes. However, research on the association between heavy metals and antimicrobial resistance is still lacking. In this study, metagenomic sequencing was used to explore the effects of the co-selection of environmentally toxic heavy metals on the resistome in manure.

Erratum: MicroRNA-100 functions as a tumor suppressor in cervical cancer via downregulating the SATB1 expression and regulating AKT/mTOR signaling pathway and epithelial-to-mesenchymal transition.

[This corrects the article DOI: 10.3892/ol.2020.

[Tracing the sources of sedimentary organic matter in Nanyue small watershed based on C, N and C/N].

Losses of organic matter in agricultural watersheds result in eutrophication and land degra-dation, which not only threaten water quality and food security, but also lead to environmental problems such as the greenhouse gases emission. We used C, N and C/N as fingerprint markers to trace the sources of sedimentary organic matter at the outlet in the Nanyue small watershed. We analyzed the spatial distribution in watershed sedimentary organic matter and soils of typical land use types, including forest, paddy field, and vegetable fields.

The chromatin-remodeling protein BAF60/SWP73A regulates the plant immune receptor NLRs.

In both plant and animal innate immune responses, surveillance of pathogen infection is mediated by membrane-associated receptors and intracellular nucleotide-binding domain and leucine-rich-repeat receptors (NLRs). Homeostasis of NLRs is under tight multilayered regulation to avoid over-accumulation or over-activation, which often leads to autoimmune responses that have detrimental effects on growth and development. How NLRs are regulated epigenetically at the chromatin level remains unclear.

Air warming and CO enrichment cause more ammonia volatilization from rice paddies: An OTC field study.

Ammonia (NH) volatilization in rice paddies may be affected by elevated atmospheric CO concentration ([CO]) and temperature due to changes in plant and soil nitrogen (N) metabolism. At present, little is known about the individual and combined effects of CO enrichment and warming on NH volatilization under field conditions. An experiment was conducted in a rice paddy in Central China, after 4 years of warming and CO enrichment using open-top chamber (OTC) devices.

Hypothalamic-pituitary-adrenal axis mediates ambient PM exposure-induced pulmonary inflammation.

Ambient fine particulate matter (PM) exposure correlates with adverse cardiometabolic effects. The underlying mechanisms have not yet been fully understood. Hypothalamic-pituitary-adrenal (HPA) axis, as the central stress response system, regulates cardiometabolic homeostasis and is implicated in the progression of various adverse health effects caused by inhalational airborne pollutant exposure.

MicroRNA-100 functions as a tumor suppressor in cervical cancer via downregulating the SATB1 expression and regulating AKT/mTOR signaling pathway and epithelial-to-mesenchymal transition.

Cervical cancer (CC) is a common malignant tumor among women worldwide, remaining the fourth most frequent cause of cancer death in women. Currently, microRNA (miRNA) is a prevalent topic in tumor-related research. The present study focused on the mechanisms of miR-100 in CC progression.

MicroRNA-126 exerts antitumor functions in ovarian cancer by targeting EGFL7 and affecting epithelial-to-mesenchymal transition and ERK/MAPK signaling pathway.

Ovarian cancer (OC) is a common gynecological malignant carcinoma worldwide. Accumulating research has revealed that multiple microRNAs (miRNAs) are abnormally expressed at different levels in various malignancies, playing vital roles in tumorigenesis. This study investigated the regulatory functions and potential mechanism of miR-126 in OC proliferation, invasion and migration.

[Responses of net assimilation rate to elevated atmospheric COand temperature at different growth stages in a double rice cropping system].

Effects of elevated atmospheric CO concentration and temperature on rice dry matter accumulation vary in planting regions and cropping systems. It remains unclear how dry matter productivity responds to factorial combination of elevated CO and temperature in the double rice cropping system of China. Field experiments were conducted using open-top chambers (OTC) to simulate different scenarios of elevated CO and/or temperature for three rotations of double rice in Jingzhou, Hubei Province.

Diffusive flux of CH and NO from agricultural river networks: Regression tree and importance analysis.

River networks in subtropical agricultural hilly region become an inconvenient greenhouse gas (GHG, methane and nitrous oxide) source because of the influence of human activities, which has caused large uncertainties for refinement of national GHG inventories and their global budget. Based on field monitoring experiments at high temporal resolution, we employed regression tree and importance analysis to identify quantitatively factors that influence the diffusive flux of GHGs to provide a scientific basis for reducing GHG emissions and controlling regional carbon and nitrogen losses. The results indicate that significant spatiotemporal variation of methane (CH) nitrous oxide (NO) diffusion occurs in all the four reaches (W1, W2, W3 and W4) of Tuojia river networks.

Air warming and CO enrichment increase N use efficiency and decrease N surplus in a Chinese double rice cropping system.

Effectiveness of N might be modified in rice cultivation under future climate change with elevated atmospheric CO concentration ([CO]). At present, limited information is available to understand how plant N uptake and N use efficiency respond to elevated [CO] and/or temperature in Chinese double rice cropping systems. A four-year field experiment was therefore conducted using open-top chambers with varying [CO] (ambient, ambient +60 μmol mol) and varying temperature (ambient, ambient +2 °C) in Hubei Province, Central China.

Effects of increased precipitation combined with nitrogen addition and increased temperature on methane fluxes in alpine meadows of the Tibetan Plateau.

Climate change and anthropogenic activities have resulted in increased atmospheric methane (CH) concentration. Increased nitrogen deposition and precipitation accompanies climate warming and can change soil carbon and nitrogen dynamics and microbial processes and alter CH fluxes. To quantify the sink of the vast alpine meadows of the Tibetan Plateau and to examine how precipitation addition (P), warming (W), and nitrogen addition (N) affect CH fluxes in alpine meadows, we conducted continuous 3-growing season experiments in an alpine meadow using the static chamber and gas chromatograph method.

Assessment of Indirect NO Emission Factors from Agricultural River Networks Based on Long-Term Study at High Temporal Resolution.

Assessment of indirect emission factors (EF) of nitrous oxide (NO) from agricultural river networks remains challenging, and results are uncertain due to limited data availability. This study compared two methods of assessing EF using data from long-term observations at high temporal resolution in a typical agricultural catchment in subtropical central China. The concentration method (method 1) and the Intergovernmental Panel on Climate Change (IPCC) 2006 method (method 2) were employed to evaluate the emission factor.