Publications by authors named "Xiaobo Pu"

Intracardiac echocardiography (ICE) has been used to guide radio-frequency catheter ablation (RFCA) for better catheter navigation and less radiation exposure in treating atrial fibrillation (AF). This retrospective cohort study enrolled 227 AF patients undergoing ICE- or traditional fluoroscopy (TF)-guided RFCA for AF in a tertiary hospital. ICE was used more often in patients with atrial tachycardia [odds ratio (OR) 3.

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Background: Pulsed field ablation (PFA) has gained attention in cardiac electrophysiology, but data on its application to paroxysmal supraventricular tachycardia are limited. This study aimed to assess the feasibility and safety of PFA and its combination with radiofrequency ablation for treating paroxysmal supraventricular tachycardia.

Methods: A prospective, multicenter, single-arm study was conducted across 8 centers in China.

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The ECG of a patient during sinus rhythm shows preexcited QRS pattern, with rS pattern in lead V1, transition in lead V2, and positive inferior leads. Following the stepwise algorithms, the location of accessory pathway (AP) was identified at anteroseptal region. However, the precordial transition in lead V2 indicates mid-septal or posteroseptal AP.

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Introduction: The optimized ablation index (AI) value for catheter ablation of atrial fibrillation (AF) remains to be defined. We aimed to compare the efficacy and safety of CLOSE protocol and lower AI protocol in paroxysmal AF.

Methods And Results: Patients with symptomatic, drug-resistant paroxysmal AF for first ablation were prospectively enrolled from September 2020 to January 2022.

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Background: To survey the unmet medical needs associated with atrium thrombus screening in Chinese patients with atrial fibrillation (AF) who underwent transesophageal echocardiography (TEE) for planned radio-frequency catheter ablation (RFCA).

Methods: This cross-sectional survey study interviewed 300 patients who underwent their first TEE for planned RFCA. The surveyed information included patients' anxiety, oropharynx pain and discomfort, time expense, and patient satisfaction related to TEE examination.

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Building prosthetics indistinguishable from human limbs to accurately receive and transmit sensory information to users not only promises to radically improve the lives of amputees, but also shows potential in a range of robotic applications. Currently, a mainstream approach is to embed electrical or optical sensors with force/thermal sensing functions on the surface or inside of prosthetic fingers. Compared with electrical sensing technologies, tactile sensors based on stretchable optical waveguides have the advantages of easy fabrication, chemical safety, environmental stability, and compatibility with prosthetic structural materials.

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Aims: To determine the association between all-cause mortality and low-density lipoprotein cholesterol (LDL-C) in patients with idiopathic cardiomyopathy (iDCM).

Background: LDL-C had long been considered as a dangerous predictor of cardiovascular diseases; however, the correlation between them was not fully clarified.

Methods: A total of 1058 patients who met the World Health Organization criteria for iDCM in West China Hospital (2009-2016) were enrolled in this retrospective study.

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Transcatheter radiofrequency ablation has been widely introduced for the treatment of tachyarrhythmias. The demand for catheter ablation continues to grow rapidly as the level of recommendation for catheter ablation. Traditional catheter ablation is performed under the guidance of X-rays.

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Objective: To analyse the characteristics and mortality of hypertrophic cardiomyopathy (HCM) patients with different body compositions.

Methods: In this study, 530 consecutive patients with HCM at West China Hospital were studied from November 2008 to May 2016. An equation based on body mass index (BMI) was used to obtain the Percent body fat (BF) and lean mass index (LMI).

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Background: We aimed to investigate whether the pressure injury risk mediates the association of left ventricular ejection fraction (LVEF) with all-cause death in patients with acute myocardial infarction (AMI) aged 80 years or older.

Methods: This retrospective cohort study included 677 patients with AMI aged 80 years or older from a tertiary-level hospital. Pressure injury risk was assessed using the Braden scale at admission, and three risk groups (low/minimal, intermediate, high) were defined according to the overall score of six different variables.

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Purpose: This meta-analysis aimed to explore the comparative short-term efficacy and safety of drug-coated balloon (DCB) vs. drug-eluting stent (DES) for treating small-vessel coronary artery lesions in diabetic patients.

Methods: We searched PubMed, EMBASE, the Cochrane Library, and China National Knowledgement Infrastructure (CNKI) for retrieving relevant studies regarding the comparison of DCB with DES in treating small-vessel coronary artery lesions in diabetic patients until May 31, 2022.

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Carrying out status monitoring and fault-diagnosis research on cutter-wear status is of great significance for real-time understanding of the health status of Tunnel Boring Machine (TBM) equipment and reducing downtime losses. In this work, we proposed a new method to diagnose the abnormal wear state of the disc cutter by using brain-like artificial intelligence to process and analyze the vibration signal in the dynamic contact between the disc cutter and the rock. This method is mainly aimed at realizing the diagnosis and identification of the abnormal wear state of the cutter, and is not aimed at the accurate measurement of the wear amount.

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Article Synopsis
  • Left ventricular hypertrophy (LVH) is common in obese individuals, and both conditions are linked to subclinical left ventricle dysfunction; the study examines their combined impact on mortality in coronary artery disease (CAD) patients.* -
  • Out of 2243 participants, 25% exhibited higher body fat, and nearly 47% had LVH; their 2.2-year follow-up revealed that those with both higher body fat and LVH had the highest mortality rates (8.2%).* -
  • Findings indicate that increased body fat significantly raises the risk of all-cause death only in patients with LVH, highlighting the importance of considering both factors in assessing mortality risk in CAD patients.*
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Background: The oscillometric blood pressure (BP) measurement technique estimates BPs from analyzing the envelop of oscillometric cuff pressure waveform. The oscillometric waveform envelope shape is associated with physiological changes and influences BP measurement accuracy. The aim of this study was to comprehensively quantify BP- and age-related changes of oscillometric waveform envelope characteristics.

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Article Synopsis
  • The study examined the role of gender in the presentation and outcomes of hypertrophic cardiomyopathy (HCM) in 576 Chinese patients, highlighting differences between males and females.
  • Female patients were older and had more severe symptoms at diagnosis compared to male patients, along with higher left ventricular outflow tract gradients.
  • Although there were no significant differences in overall or cardiovascular mortality rates between genders, females had a higher rate of being rehospitalized due to heart failure.
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It is clinically important to evaluate the performance of a newly developed blood pressure (BP) measurement method under different measurement conditions. This study aims to evaluate the performance of using deep learning-based method to measure BPs and BP change under non-resting conditions. Forty healthy subjects were studied.

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Article Synopsis
  • - Atrial fibrillation (AF) is the most common heart rhythm disorder, which can lead to strokes; combining catheter ablation with left atrial appendage occlusion (LAAO) in a single procedure could help reduce stroke risks and improve AF symptoms for high-risk patients.
  • - A meta-analysis of 18 studies found this "one-stop" intervention to have high procedural success (98%) and low rates of adverse events like AF recurrence (24%), strokes (1%), and major complications (1%).
  • - The analysis supports that performing catheter ablation and LAAO together is a safe and effective treatment strategy for managing nonvalvular AF.
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Background: Contemporary heart failure medications have led to considerable improvement in the survival of patients with heart failure. However, limited evidence is available regarding the effect of those medications in patients with idiopathic dilated cardiomyopathy (IDCM), particularly in China. We sought to analyze the trends in clinical characteristics and the prescription rate of recommended therapies and its prognostic impact in patients with IDCM.

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Background: Ageing is a risk factor for both coronary artery disease (CAD) and reduced renal function (RRF), and it is also associated with poor prognosis in patients with CAD or RRF. However, little is known about whether the impact of RRF on clinical outcomes are different in CAD patients at different age groups. This study aimed to investigate whether ageing influences the effect of RRF on long-term risk of death in patients with CAD.

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Background: Exercise-based cardiac rehabilitation (CR) has been recognized as an essential component of the treatment for coronary heart disease (CHD). Determining the efficacy of modern alternative treatment methods is the key to developing exercise-based CR programs.

Methods: Studies published through June 6, 2016, were identified using MEDLINE, EMBASE, and the Cochrane Library.

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Background: The impact of renal function on the prognostic value of N-terminal pro-B-type natriuretic peptide (NT-proBNP) remains unclear in coronary artery disease (CAD). This study sought to investigate the value of using NT-proBNP level to predict prognoses of CAD patients with different estimated glomerular filtration rates (eGFRs).

Methods: A retrospective analysis was conducted from a single registered database.

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Background: Elderly patients with coronary artery disease (CAD) frequently complicated with more cardiovascular risk factors, but received fewer evidence-based medications (EBMs). This study explored the association of EBMs compliance in different age groups and the risk of long-term death.

Methods: A retrospective analysis was conducted from a single registered database.

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Background: TAVR is a rapidly spreading treatment option for severe aortic valve stenosis. Significant coronary artery disease (CAD) is present in 40% to 75% of patients undergoing TAVR. However, when to treat the concomitant coronary artery lesions is controversial.

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