Utilizing a suture-constrained covered stent for shunt reduction to treat transjugular intrahepatic portosystemic shunt-related refractory hepatic encephalopathy: a retrospective study.

Purpose: Refractory hepatic encephalopathy (RHE) can occur as a consequence of excessive shunting following the creation of a transjugular intrahepatic portosystemic shunt (TIPS). We describe a technique that utilizes a suture-constrained covered stent for shunt reduction to treat TIPS-related RHE.

Materials And Methods: Between January 2017 and September 2023, 25 patients with TIPS-related RHE who underwent shunt reduction utilizing a suture-constrained covered stent were reviewed.

Med23 deficiency reprograms the tumor microenvironment to promote lung tumorigenesis.

Background: Lung cancer is the leading cause of cancer-related death worldwide. We previously found that Mediator complex subunit 23 (MED23) is important for the tumourigenicity of lung cancer cells with hyperactive Ras activity in vitro, although the in vivo function of MED23 in lung tumourigenesis remains to be explored.

Methods: In this study, we utilized well-characterized Kras-driven non-small cell lung cancer mouse model to investigate the role of MED23 in lung cancer.

Safety and efficacy of self-expandable metallic stent combined with I brachytherapy for the treatment of malignant obstructive jaundice.

Background: Several previous studies demonstrated that the combination of self-expandable metallic stents (SEMS) and I seed implantation might prolong stent patency and obtain survival benefits for malignant obstructive jaundice (MOJ) patients. However, these studies rarely mentioned a comparison between CT-guided intratumoral I seed implantation and intraluminal I seed strand insertion combined with stenting for the management of MOJ. This study aimed to further evaluate the safety and efficacy of SEMS combined with I brachytherapy in the management of unresectable MOJ.

Outcomes of two types of iodine-125 seed delivery with metal stents in treating malignant biliary obstruction: a systematic review and meta-analysis.

Purpose: To conduct a meta-analysis comparing the efficacy and safety of two types of iodine-125 (I-125) seed delivery with metal stents (the study group) versus conventional metal stents (the control group) in patients with malignant biliary obstruction (MBO).

Methods: Our team systematically searched the PubMed, Embase, and Cochrane Library databases for relevant studies published from January 2012 up to July 2021. Survival time and stent dysfunction were the primary measured outcomes.

CT-guided I brachytherapy for hepatocellular carcinoma in high-risk locations after transarterial chemoembolization combined with microwave ablation: a propensity score-matched study.

Background: This study aimed to evaluate the safety and efficacy of I brachytherapy combined with transarterial chemoembolization (TACE) and microwave ablation (MWA) for unresectable hepatocellular carcinoma (HCC) in high-risk locations.

Patients And Methods: After 1:2 propensity score matching (PSM), this retrospectively study analyzed 49 patients who underwent TACE +MWA+I brachytherapy (group A) and 98 patients who only received TACE +MWA (group B). The evaluated outcomes were progression-free survival (PFS), overall survival (OS), and treatment complications.

Effect of percutaneous stenting strategy of unresectable malignant hilar biliary obstruction by three-dimensional reconstruction volumetry.

Purpose: To explore clinical outcomes of percutaneous stent implantation using volumetric criteria for unresectable malignant hilar biliary obstruction (MHBO). Additionally, aimed to identify the predictors of patients' survival.

Methods: Seventy-two patients who were initially diagnosed with MHBO between January 2013 to December 2019 in our center were retrospectively included.

Sevoflurane reverses cisplatin resistance in neuroblastoma cells through the linc00473/miR-490-5p/AKT1 axis.

Objectives: To determine whether sevoflurane regulates cisplatin resistance in neuroblastoma cells.

Methods: The SH-SY5Y cell line with cisplatin-resistant phenotype (SH-SY5Y-SR) was generated. Cells were co-treated with sevoflurane and cisplatin to seek the sevoflurane function on cisplatin resistance.

Effect of Biliary Tract Invasion with Obstructive Jaundice on the Prognosis of Patients With Unresectable Hepatocellular Carcinoma.

Rationale And Objectives: Biliary tract invasion (BTI) is associated with poor outcomes in patients with hepatocellular carcinoma (HCC). However, the presence of a BTI is a neglected variable for staging in the current guidelines. This study aimed to explore the effects of BTI with obstructive jaundice on the prognosis of patients with unresectable HCC.

Improve the Interfacial Properties between Poly(arylene sulfide sulfone) and Carbon Fiber by Double Polymeric Grafted Layers Designed on a Carbon Fiber Surface.

Double polymeric grafted layer is constructed by two steps of chemical reaction, in which two polymers had been used, respectively polydopamine (PDA) film and modified PASS (NH-PASS) resin containing amine group, as the interphase in carbon fiber reinforced poly(arylene sulfide sulfone) (PASS) composite (CF/PASS) to work on enhancing the interfacial property. All the test results of chemical components and chemical structures on the carbon fiber surface show that the double polymeric grafted layer was constructed successfully with PDA and NH-PASS chains. And obvious characteristics of thin PDA film and a polymer layer can be clearly seen in the morphology of modified carbon fiber.

High Capacitive Antimonene/CNT/PANI Free-Standing Electrodes for Flexible Supercapacitor Engaged with Self-Healing Function.

In virtue of the high electrochemical activity and inherent flexibility, polyaniline (PANI) is an ideal electrode material for flexible supercapacitors (SCs). However, in practical applications, the inevitable agglomeration of PANI leads to low capacitance, poor rate performance, and cycling stability. Here, antimonene (Sb) nanosheets with ultrathin thickness, excellent mechanical strength, and flexibility are introduced into the carbon nanotube (CNT) framework for PANI electrodeposition via simple vacuum filtration, which enables the continuous and uniform growth of PANI.

Efficient Na-storage in a LiTiO anode to expand the voltage-window for full SIBs of high energy density.

The stable storage of sodium ions always presents some difficulties for sodium-based dual-ion batteries (S-DIBs), such as the irreversibility of guest-storage and kinetic hindrance in the anode. Based on the low strain volume and stable phase structure, herein, lithium titanate (LTO, LiTiO) was developed to store sodium ions between the working potential (∼0.8 V), which expands the lower plateau over than that of lithium ion storage (∼1.

Studies on transmittance modulation and ions transfer kinetic based on capacitive-controlled 2D VOinverse opal film for electrochromic energy storage application.

Two-dimensional vanadium pentoxide inverse opal (2D VOIO) architecture was fabricated by polystyrene (PS) sphere template assisted electrodeposition process. In comparison to the un-templated VOfilm, the 2D VOIO film exhibited a highly ordered hexagonal close-packed bowel-like array, as well as noticeable electrochromism, such as transmittance modulation up to 42.6% at 800 nm, high coloration efficiency (28.

Selective Catalytic Oxidation of Benzyl Alcohol to Benzaldehyde by Nitrates.

In this paper, ferric nitrate was used to oxidize benzyl alcohol in a mild condition and demonstrated its better performance compared to HNO. In the reaction, the conversion rate and product selectivity could be both as high as 95% in N atmosphere, while the benzaldehyde yield also reached 85% in air. Similar to Fe(NO)·9HO, the other metallic nitrates such as Al(NO)·9HO and Cu(NO)·3HO could also oxidize the benzyl alcohol with high activity.

Intrinsic acid resistance and high removal performance from the incorporation of nickel nanoparticles into nitrogen doped tubular carbons for environmental remediation.

Nitrogen doped tubular magnetic carbons embedded with nickel nanoparticles (Ni@NTMCs) were prepared via a simple pyrolysis process and employed as the effective adsorbents for the Cr(VI) removal. Ni@NTMCs with as high as 10.63 at.

Percutaneous intratumoral injection of gemcitabine plus cisplatin mixed with fibrin glue for advanced pancreatic carcinoma: Case Report.

Rationale: The aim of this study was to determine the effectiveness of intratumoral injection of chemotherapeutics in improving the quality of life and survival of patients with pancreatic carcinoma.

Patient Concerns: We present a case series of 5 patients with unresectable pancreatic adenocarcinoma.

Diagnoses: Patients diagnosed with unresectable poorly differentiated pancreatic ductal adenocarcinoma by intraoperative frozen biopsyor percutaneous biopsy.

Design, synthesis, and biological evaluation of novel quinazolinyl-diaryl urea derivatives as potential anticancer agents.

Through a structure-based molecular hybridization approach, a series of novel quinazolinyl-diaryl urea derivatives were designed, synthesized, and screened for their in vitro antiproliferative activities against three cancer cell lines (HepG2, MGC-803, and A549). Six compounds (7 g, 7 m, 7 o, 8 e, 8 g, and 8 m) showed stronger activity against a certain cell line compared with the positive reference drugs sorafenib and gefitinib. Among the six compounds, 8 g exhibited the strongest activity.

Synthesis, Fluorescence Properties, and Antiproliferative Potential of Several 3-Oxo-3H-benzo[f]chromene-2-carboxylic Acid Derivatives.

In this study, two series of 3-oxo-3H-benzo[f]chromene-2-carboxylic acid derivatives (compounds 5a-i and 6a-g) were synthesized. Their in vitro proliferation inhibitory activities against the A549 and NCI-H460 human non-small cell lung cancer (NSCLC) cell lines were evaluated. Their photophysical properties were measured.

Preparation of halloysite nanotube-supported gold nanocomposite for solvent-free oxidation of benzyl alcohol.

Gold nanoparticles supported on halloysite nanotubes (Au/HNTs) were prepared by a homogeneous deposition-precipitation method. The specific characteristics of the catalyst were characterized in detail, in relation to their performance for solvent-free oxidation of benzyl alcohol. The particular structure of the catalyst resulted in high catalytic activity and stability compared with other supported gold catalysts.

A microalgae residue based carbon solid acid catalyst for biodiesel production.

Biodiesel production from microalgae is recognized as one of the best solutions to deal with the energy crisis issues. However, after the oil extraction from the microalgae, the microalgae residue was generally discarded or burned. Here a novel carbon-based solid acid catalyst derived from microalgae residue by in situ hydrothermal partially carbonization were synthesized.

4-Dimethyl-amino-N'-(4-nitro-benzyl-idene)benzohydrazide methanol monosolvate.

In the title compound, C(16)H(16)N(4)O(3)·CH(3)OH, the aromatic rings form a dihedral angle of 0.4 (2)°. The nitro group is twisted from the attached benzene ring by 7.

Room temperature synthesis of a novel gamma-MnO2 hollow structure for aerobic oxidation of benzyl alcohol.

A novel gamma-MnO(2) hollow structure has been synthesized at room temperature using a simple chemical reaction between MnSO(4) and KMnO(4) in aqueous solution without using any templates, surfactants, catalysts, calcination and hydrothermal processes. The synthesized gamma-MnO(2) hollow structure was characterized by x-ray diffraction (XRD), scanning electron microscopy (SEM), transmission electron microscopy (TEM) and BET analysis. It was found that the hollow structure consisting of short gamma-MnO(2) nanorods with diameters of 5-10 nm and lengths of 50-100 nm could form when the MnSO(4)/KMnO(4) mole ratio was equal to or larger than 2.

Capacitance dependent catalytic activity of RuO2 x xH2O/CNT nanocatalysts for aerobic oxidation of benzyl alcohol.

The activity of RuO(2) x xH(2)O/CNT for benzyl alcohol oxidation can be predicted by the specific capacitance (SC) of RuO(2), suggesting that highly active RuO(2) nanocatalysts are also good supercapacitor materials with SC high up to 1500 F g(RuO(2))(-1).